Could early blood thinners save heart transplants?
NCT ID NCT04770012
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if giving blood thinners (aspirin or clopidogrel) soon after a heart transplant can prevent a common complication called cardiac allograft vasculopathy, which narrows the heart's arteries. About 135 adult heart transplant recipients will be randomly assigned to receive either a blood thinner or a placebo. The goal is to see if this approach is feasible for a larger trial and whether it can improve long-term transplant success.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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St.Pauls Hospital
RECRUITINGVancouver, British Columbia, V6Z 1Y6, Canada
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Toronto General Hospital UHN
RECRUITINGToronto, Ontario, M5G 2C4, Canada
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University of Ottawa Heart Institute
RECRUITINGOttawa, Ontario, K1Y 4W7, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could skipping the breathing tube make heart transplants safer?
- Can a new drug combo shield young hearts from transplant complications?
- Strength training may boost heart transplant candidates' fitness and quality of life
- Heart transplant patients may soon skip invasive artery checks with new PET scan study
- New methods could spot hidden heart artery disease sooner after transplant
- Heart transplant patients get new weapon against hidden artery damage