Could early blood thinners save heart transplants?

NCT ID NCT04770012

Recruiting now Disease control Sponsor: Ottawa Heart Institute Research Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if giving blood thinners (aspirin or clopidogrel) soon after a heart transplant can prevent a common complication called cardiac allograft vasculopathy, which narrows the heart's arteries. About 135 adult heart transplant recipients will be randomly assigned to receive either a blood thinner or a placebo. The goal is to see if this approach is feasible for a larger trial and whether it can improve long-term transplant success.

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Conditions

The condition(s) this trial relates to.

chronic transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC ALLOGRAFT VASCULOPATHY HEART TRANSPLANT

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

St.Pauls Hospital
RECRUITING

Vancouver, British Columbia, V6Z 1Y6, Canada

Contact
Toronto General Hospital UHN
RECRUITING

Toronto, Ontario, M5G 2C4, Canada

Contact
University of Ottawa Heart Institute
RECRUITING

Ottawa, Ontario, K1Y 4W7, Canada

Contact