New registry to see if a heart-preserving device can save more lives in transplants
NCT ID NCT05915299
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This registry will follow up to 100,000 heart transplant recipients to compare outcomes when donor hearts are preserved using the OCS Heart system versus traditional cold storage. The goal is to see if the OCS Heart system, which keeps donor hearts warm and beating during transport, leads to better patient and graft survival. No new treatments are being tested; instead, researchers will analyze existing data from a national transplant database.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this registry could confirm that the OCS Heart system helps more donor hearts be used safely, potentially increasing transplant access.
What could go wrong
This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may be influenced by patient selection or other factors.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Atrium Health
RECRUITINGCharlotte, North Carolina, 28203, United States
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Aurora St Luke's Medical Center
RECRUITINGMilwaukee, Wisconsin, 53215, United States
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Banner University Medical Center Phoenix
RECRUITINGPhoenix, Arizona, 85006, United States
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Baylor Scott and White
RECRUITINGDallas, Texas, 75226, United States
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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Boulder
RECRUITINGBoulder, Colorado, 80309, United States
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Columbia University Irving Medical Center/ New York Presbyterian Hospital
RECRUITINGNew York, New York, 10032, United States
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Duke University
RECRUITINGDurham, North Carolina, 27710, United States
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Emory University Hospital
RECRUITINGAtlanta, Georgia, 30322, United States
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Froedtert & the Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Henry Ford
RECRUITINGDetroit, Michigan, 48202, United States
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Lucile Packard Children's Hospital Stanford
RECRUITINGPalo Alto, California, 94304, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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Mayo Clinic Florida
RECRUITINGJacksonville, Florida, 32224, United States
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Mayo Clinic Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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Minneapolis Heart Institute
RECRUITINGMinneapolis, Minnesota, 55407, United States
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Montefiore
RECRUITINGThe Bronx, New York, 10467, United States
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Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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Stanford University
RECRUITINGPalo Alto, California, 94304, United States
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Tampa General Hospital
RECRUITINGTampa, Florida, 33606, United States
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The Christ Hospital
RECRUITINGCincinnati, Ohio, 45219, United States
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Tufts Medical Center
RECRUITINGBoston, Massachusetts, 02111, United States
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University of California San Diego
RECRUITINGLa Jolla, California, 92037, United States
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University of California San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
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University of Kentucky
RECRUITINGLexington, Kentucky, 40506, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55414, United States
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University of North Carolina
RECRUITINGChapel Hill, North Carolina, 48109, United States
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University of Pittsburgh Medical Center
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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University of Texas Southwestern
RECRUITINGDallas, Texas, 75390, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84132, United States
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University of Washington Medical Center
RECRUITINGSeattle, Washington, 98105, United States
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Virginia Commonwealth University Health
RECRUITINGRichmond, Virginia, 23298, United States
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Westchester Medical Center
RECRUITINGValhalla, New York, 10595, United States
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Yale New Haven Hospital
RECRUITINGNew Haven, Connecticut, 06510, United States
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