Strength training may boost heart transplant candidates' fitness and quality of life

NCT ID NCT06426173

Recruiting now Symptom relief Sponsor: University of Sao Paulo General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 12-week resistance training program can improve physical function, quality of life, and heart-related biomarkers in people with heart failure who are on the waiting list for a heart transplant. Participants will be randomly assigned to either the exercise program or usual care. The goal is to see if strength training can help patients stay stronger and feel better while they wait for a new heart.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: resistance training program
What this could lead to: If effective, this exercise program could become a standard way to improve strength and well-being for people waiting for a heart transplant.
What could go wrong: This is a small, early-stage trial with 50 participants, so results may not apply to all patients. Exercise may be challenging for very frail individuals.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE HEART TRANSPLANT

Contacts and locations

Locations

Instituto do Coração - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
RECRUITING

São Paulo, São Paulo, 05403-000, Brazil

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