New vaccine aims to fight hidden virus in people with HIV

NCT ID NCT05099965

Completed ⭐️ VACCINE ⭐️ Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a vaccine called Triplex® in 94 adults who have both HIV and cytomegalovirus (CMV). The goal was to see if the vaccine is safe and helps the immune system control CMV. Participants received two shots of the vaccine or a placebo over 4 weeks and were followed for 48 weeks.

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Conditions

The condition(s) this trial relates to.

cytomegalovirus infection HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CYTOMEGALOVIRUS INFECTIONS HIV INFECTIONS VACCINE

Contacts and locations

Locations

Alabama CRS

Birmingham, Alabama, 35222, United States
Case Clinical Research Site

Cleveland, Ohio, 44106, United States
Chapel Hill CRS

Chapel Hill, North Carolina, 27599, United States
Houston AIDS Research Team CRS

Houston, Texas, 77009, United States
Massachusetts General Hospital CRS (MGH CRS)

Boston, Massachusetts, 02114, United States
Penn Therapeutics, CRS

Philadelphia, Pennsylvania, 19104, United States
UCLA CARE Center CRS

Los Angeles, California, 90035-4709, United States
UCSD Antiviral Research Center

San Diego, California, 92103, United States
Ucsf Hiv/Aids Crs

San Francisco, California, 94110, United States
University of Colorado Hospital CRS

Aurora, Colorado, 80045, United States
University of Pittsburgh CRS

Pittsburgh, Pennsylvania, 15213, United States
Washington University Therapeutics (WT) CRS

St Louis, Missouri, 63110, United States

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