New vaccine aims to fight hidden virus in people with HIV

NCT ID NCT05099965

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a vaccine called Triplex® in 94 adults who have both HIV and cytomegalovirus (CMV). The goal was to see if the vaccine is safe and helps the immune system control CMV. Participants received two shots of the vaccine or a placebo over 4 weeks and were followed for 48 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cytomegalovirus infection HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alabama CRS

    Birmingham, Alabama, 35222, United States

  • Case Clinical Research Site

    Cleveland, Ohio, 44106, United States

  • Chapel Hill CRS

    Chapel Hill, North Carolina, 27599, United States

  • Houston AIDS Research Team CRS

    Houston, Texas, 77009, United States

  • Massachusetts General Hospital CRS (MGH CRS)

    Boston, Massachusetts, 02114, United States

  • Penn Therapeutics, CRS

    Philadelphia, Pennsylvania, 19104, United States

  • UCLA CARE Center CRS

    Los Angeles, California, 90035-4709, United States

  • UCSD Antiviral Research Center

    San Diego, California, 92103, United States

  • Ucsf Hiv/Aids Crs

    San Francisco, California, 94110, United States

  • University of Colorado Hospital CRS

    Aurora, Colorado, 80045, United States

  • University of Pittsburgh CRS

    Pittsburgh, Pennsylvania, 15213, United States

  • Washington University Therapeutics (WT) CRS

    St Louis, Missouri, 63110, United States