New study Fine-Tunes malaria drug dosing for kids

NCT ID NCT05750459

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at how the malaria drug artesunate works in 90 Ugandan children aged 6 months to 14 years with severe malaria. Researchers measured drug levels in the blood and tracked vital signs like temperature and blood pressure to see how the body responds. The goal was to better understand the right dose for children to improve treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

artesunate

What this could lead to

If successful, this study could help doctors give the right dose of IV artesunate to children with severe malaria, potentially improving recovery.

What could go wrong

This is a small, single-site study that measured drug levels and body responses, not whether the drug works better than other treatments. Results may not apply to all children.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malaria Plasmodium falciparum malaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Makerere University-Infectious Diseases Institute

    Kampala, Uganda