TYPE 2 DIABETES

This study tested a new insulin called THDB0206 against a commonly used insulin (lispro) in over 1000 Chinese adults with type 2 diabetes. Both insulins were taken alongside a long-acting insulin (glargine). The goal was to see how well each controlled blood sugar over 26 weeks. …

This study looked at how well adults with obesity or complicated overweight follow and tolerate different very-low-calorie ketogenic diets. Participants chose one of four diet plans, ranging from natural foods to meal replacements, and were followed for about 26 weeks. The goal w…

This study looked at whether a DASH-style diet (modified for diabetes) combined with lower salt intake can lower blood pressure in adults with type 2 diabetes and high blood pressure. 105 participants were fed different diets for 5-week periods. The main goal was to see if the DA…

This study tested a new investigational medicine called CagriSema (a combination of two drugs) in 189 adults with type 2 diabetes. Participants received either CagriSema or a placebo once a week for about a year. The goal was to see if CagriSema could lower blood sugar and body w…

This study tested whether providing medically tailored meals and nutrition support for six months can improve blood sugar control and reduce food insecurity in adults with type 2 diabetes. A total of 281 participants were enrolled. The approach combines healthy food delivery with…

This study looked at 120 shift workers with prediabetes or type 2 diabetes who were overweight or obese. Participants followed one of three low-calorie diets for 12 weeks, each with a different amount of protein at dinner. The goal was to see which diet best improved blood sugar,…

This study tested a new investigational drug called CagriSema against a currently available medicine, tirzepatide, in over 1,000 adults with type 2 diabetes. Participants received weekly injections of either drug for up to a year and a half. The goal was to see which treatment be…

This study tested a program that combines diabetes coaching, financial rewards, and continuous glucose monitoring to help adults with type 2 diabetes improve their blood sugar management. 26 participants completed the program. The goal was to see if this approach helps people sti…

This study tested the drug tirzepatide in 206 Chinese adults with type 2 diabetes who were not on other diabetes medicines. The goal was to see if tirzepatide could lower blood sugar levels better than a placebo. Participants took tirzepatide or a dummy pill for several weeks, an…

This study tested whether an automated insulin delivery (AID) system works better than standard insulin shots for managing blood sugar in hospitalized adults with type 1 or type 2 diabetes. 130 patients on general medical or surgical floors were randomly assigned to use either th…

This study tested a new drug called HRS-7535 in 284 adults with type 2 diabetes whose blood sugar was not well controlled by diet and exercise alone. Participants received either the drug or a placebo for 32 weeks. The main goal was to see if the drug lowered blood sugar levels (…

This study tested whether a tablet app used by community health workers could improve the detection and management of anemia, gestational diabetes, and high blood pressure in over 3,400 pregnant women in rural India. Women in the intervention group were screened at multiple point…

This study looked at whether canagliflozin, a diabetes medicine, can reduce scarring in the heart muscle of people with type 2 diabetes who are at high risk for heart problems. 45 adults took the drug, and researchers used heart scans to measure changes in fibrosis. The goal was …

This early-stage study tested a new daily oral medication called LY3549492 in 36 Chinese adults with type 2 diabetes. The main goal was to check safety and how the drug moves through the body. Participants took the pill or a placebo for several weeks, and researchers monitored si…

This study tested a connected insulin management platform in 36 people with type 1 or type 2 diabetes who use insulin. The goal was to see if the platform helped them take their insulin doses on time and keep their blood sugar in a healthy range. Participants used a continuous gl…

This study looked at whether a plant-based diet that avoids certain harmful compounds called oxysterols can improve insulin production in African Americans with prediabetes or early type 2 diabetes. Twelve participants followed either a standard diabetes diet or a plant-based ver…

This study looked at whether people with type 2 diabetes who get regular support from nurses and dietitians can better control their blood sugar and weight. 398 adults with type 2 diabetes first received a week of education on diet and exercise. Then, half were assigned to freque…

This study looked at how three popular healthy diets—Mediterranean, DASH, and MIND—affect blood sugar, cholesterol, and body measurements in people with type 2 diabetes. Researchers tracked 90 adults over 19 years old, measuring things like weight, waist size, and lab values. The…

This study tested whether taking a probiotic called Hafnia alvei for 90 days after gastric bypass surgery helps people lose more weight and control their blood sugar better. 49 adults who had the surgery took either the probiotic or a placebo. Researchers tracked their weight, bl…

This study tested whether adding regular pharmacist-led education and support to usual diabetes care helps patients with type 2 diabetes better control their blood sugar. 122 adults in Nigeria took part, with half receiving standard care and half also meeting with a pharmacist fo…

This study tested whether using an automated insulin delivery (AID) system for just 10 days could help people with type 2 diabetes safely and quickly adjust their long-acting insulin doses. 23 adults with type 2 diabetes and high blood sugar levels participated. The experimental …

This study tested a new once-daily pill, orforglipron, against an existing pill (semaglutide) in adults with type 2 diabetes whose blood sugar was not well controlled by metformin alone. About 1,700 participants took one of the two pills for 61 weeks. The main goal was to see whi…

This study tested a new magnetic system that creates a connection between two parts of the small intestine, bypassing a section to help with weight loss and blood sugar control. Nine adults with obesity and type 2 diabetes received the procedure. The goal was to see if the magnet…

This study tested whether a virtual weight management program combined with a continuous glucose monitor could help adults with type 2 diabetes lower their blood sugar levels. 152 overweight or obese adults with type 2 diabetes participated. The program was delivered through a di…

This study tested a once-daily pill called orforglipron in 546 adults with type 2 diabetes whose blood sugar was not well controlled despite using insulin glargine (with or without other diabetes medications). The goal was to see if adding orforglipron could safely lower blood su…

This study looked at whether a three-month supervised exercise program can help men with type 2 diabetes, prediabetes, or obesity improve their blood sugar, body composition, and fitness. Three hundred sedentary men aged 35-65 took part in regular training sessions at a fitness c…

This early-stage study tested a new drug called AZD5004 in 45 Chinese adults who were overweight or obese, some with type 2 diabetes. The main goal was to check if the drug is safe and how the body processes it, compared to a placebo. Researchers measured side effects and drug le…

This study compared several common diabetes medications when added to metformin in 7,850 adults with type 2 diabetes. The goal was to see which combination best kept blood sugar under control over time. Participants were followed to see how long their blood sugar stayed below a c…

This early-stage study looked at how the drug rongliflozin behaves in 32 people with type 2 diabetes who have normal, mildly, or moderately reduced kidney function. Researchers measured drug levels in the blood and how much sugar was passed in urine after a single dose. The goal …

This study tested whether a high-intensity medical weight loss program, supported by a digital platform, could help people with type 2 diabetes achieve remission. 64 participants with recent diabetes diagnosis and obesity were enrolled. The program used tailored treatment plans, …

This study tested whether the drug retatrutide can improve kidney function in 146 adults who are overweight or obese and have chronic kidney disease, with or without type 2 diabetes. Participants received the drug or a placebo for about 31 weeks. The main goal was to see if retat…

This study looked at whether adding a nurse trained in diabetes care to the treatment team helps breast cancer patients with diabetes or prediabetes manage their blood sugar during cancer therapy. 74 patients were split into two groups: one worked with the nurse, the other did no…

This study tested a new medicine called HRS-7535 in 155 adults with type 2 diabetes whose blood sugar was not well controlled despite taking metformin and an SGLT2i. Participants received either the new drug or a placebo for 16 weeks. The main goal was to see if HRS-7535 lowers H…

This study tested two diets for people with type 2 diabetes: a very low-carbohydrate diet and a plate-method diet. Over 12 months, researchers measured blood sugar control and body changes in 182 adults. The goal was to see which approach works better for managing diabetes.

This early-stage study tested a new drug called CT-996 in 94 overweight or obese adults, including some with type 2 diabetes. The main goal was to check safety and how the drug moves through the body. Researchers also looked at how it affects weight and blood sugar, but this is j…

This study tested a new once-daily pill called orforglipron against an existing drug, dapagliflozin, in adults with type 2 diabetes whose blood sugar was not well controlled by metformin alone. About 962 participants took either orforglipron or dapagliflozin for roughly 46 weeks.…

This study tested a telephone-delivered program for 100 African Americans aged 50 and older with poorly controlled type 2 diabetes. The program combined diabetes self-management education with help resolving unmet social needs, like food or housing. Participants were randomly ass…

This study tested a new magnetic system that creates a shortcut in the digestive tract to help adults with obesity and type 2 diabetes lose weight and control blood sugar. Fifteen participants received the procedure to see if the connection could be made safely and effectively. T…

This study tested whether taking magnesium oxide pills can improve blood sugar control in people with type 2 diabetes. 247 adults with high blood sugar took either magnesium or a placebo for 12 months. Researchers measured changes in HbA1c and fasting blood sugar to see if magnes…

This study tested whether a 6-week mindfulness program could help teens at risk for type 2 diabetes who also have depression. 120 teens aged 12-17 took part. The goal was to see if the program was practical and well-received, and if it could lower depression and insulin resistanc…

This study tested a new device used during an endoscopy to regenerate the lining of the upper small intestine in 65 adults with type 2 diabetes. The goal was to see if the procedure is safe and can help improve blood sugar control. Participants were on stable diabetes medications…

This study looked at how the diabetes drug sitagliptin affects levels of anti-rejection medicines (tacrolimus and sirolimus) in kidney transplant patients with type 2 diabetes. It also checked for side effects and blood sugar control over 3 months. 16 people who were at least 1 y…

This study tested a 4-month online program focused on eating a low-carbohydrate breakfast for adults with poorly controlled type 2 diabetes. 119 participants joined to see if the program was easy to follow and improved blood sugar levels, weight, and medication needs. The goal wa…

This study tested a 12-month program that provides remote support to older adults with type 2 diabetes. Participants received personalized goal setting, phone-based care management, and help connecting to community resources. The goal was to improve blood sugar control and qualit…

This early-phase study tested a new long-acting injection called NEX-22A in 12 adults with type 2 diabetes. The goal was to see how the drug moves through the body and if it is safe. Participants received a single shot, and researchers measured drug levels and side effects over t…

This study tested whether personalized dietary advice helps people with early type 2 diabetes control their blood sugar better than standard advice or usual care. About 255 to 294 adults with early-stage diabetes took part. They were split into three groups: one got a standard di…

This study tested a family-focused diabetes education program in Marshallese faith-based organizations. 321 adults with type 2 diabetes and a family member took part. The program aimed to improve blood sugar control over 2 years by teaching self-management skills in a group setti…

This study tested whether pyridoxamine, a form of vitamin B6, can improve the function of small blood vessels in people with type 2 diabetes. The researchers wanted to see if it could help prevent or reduce complications in the eyes, kidneys, and nerves. Forty adults with type 2 …

This study compared two diabetes medications, dapagliflozin and metformin, in over 2,000 people with early type 2 diabetes. The goal was to see which drug better prevents serious complications like heart attack, stroke, kidney disease, and eye problems. Participants had diabetes …

This study tested a new once-weekly medicine called IcoSema against a daily insulin shot in 485 adults with type 2 diabetes whose blood sugar was not well controlled by pills. IcoSema combines two drugs to lower blood sugar and may also help with weight loss. The goal was to see …

This study tested a home-based, telephone-delivered therapy program for low-income seniors aged 65 and older with poorly controlled type 2 diabetes. The program, called Home DM-BAT, involved 8 sessions with a diabetes nurse educator to help participants manage their condition. Th…

This pilot study tested two health coaching strategies for Black adults with stage 1 obesity and conditions like high blood pressure, prediabetes, or high cholesterol. One strategy focused on weight loss, while the other focused on increasing physical activity without targeting w…

This completed study looked at how two diabetes medications, dapagliflozin and empagliflozin, affect weight, cholesterol, and inflammation in 260 obese adults newly diagnosed with type 2 diabetes. Over six months, participants took either metformin (standard care) or one of the t…

This study tested whether combining continuous glucose monitors with monthly telehealth appointments with a pharmacist could help people with uncontrolled type 2 diabetes. 46 adults from a community health center took part. Researchers measured blood sugar levels and surveyed par…

This study compared a once-daily pill called orforglipron to insulin glargine in about 2,700 adults with type 2 diabetes who were also overweight or obese and had increased heart or kidney risk. The main goal was to see if orforglipron could delay or prevent major heart problems …

This study tested whether taking sodium butyrate tablets for 12 weeks, along with a reduced-calorie diet, helps overweight or obese people lose more weight and improve blood sugar control compared to a placebo. The trial included 46 adults aged 30-70 with or without type 2 diabet…

This study tested an experimental drug called MCI-196 in 183 adults with type 2 diabetes. Over 12 weeks, researchers measured changes in blood sugar and cholesterol levels compared to a placebo. The goal was to see if the drug can help control diabetes and improve related health …

This study tested whether using a mobile health app (Undermyfork) along with a continuous glucose monitor (Dexcom G7) helps people with type 2 diabetes control their blood sugar better than standard care. About 91 adults with type 2 diabetes who were not on rapid-acting insulin t…

This study tested whether taking a mangosteen supplement (500 mg twice daily) along with the standard diabetes drugs sitagliptin and metformin could improve blood sugar control in adults newly diagnosed with type 2 diabetes. 47 patients completed the 12-week trial. The study meas…

This study tested a new consultation method called M2-PRIME, which uses a simple analogy (garbage and lorry) to explain how the body handles sugar. 106 adults with type 2 diabetes on insulin and high blood sugar took part. Over three visits in six months, doctors used this approa…

This study tested a new insulin patch pump system in 161 adults with type 1 or type 2 diabetes who needed intensive insulin therapy. Participants were randomly assigned to use either the new patch pump or a standard insulin pump for 7 days in a hospital. The main goal was to see …

This study looked at whether drinking artificially sweetened diet beverages affects blood sugar control in adults with type 2 diabetes. About 181 participants were randomly assigned to drink either their usual diet beverage or plain water daily for 24 weeks. The main goal was to …

This study tested a new medication called MP-513 (Teneligliptin) in 324 Japanese adults with type 2 diabetes. The goal was to see if the drug could safely lower blood sugar levels over 12 weeks compared to a placebo. Researchers measured changes in HbA1c (a long-term blood sugar …

This study looked at whether making U.S. dietary guidelines more culturally relevant for African Americans could improve diet quality and reduce type 2 diabetes risk. Over 12 weeks, 63 overweight or obese African American adults at risk for diabetes followed one of three diet pat…

This study tested a once-daily oral medication called orforglipron in 559 adults with type 2 diabetes whose blood sugar was not well controlled by diet and exercise alone. Participants received either the drug or a placebo for about 54 weeks. The main goal was to see if the drug …

This study tested whether adding overripe banana powder to the diet helps adults with type 2 diabetes control their blood sugar. Sixty participants took either the banana supplement or a placebo for 12 weeks. Researchers measured changes in blood sugar, insulin, and blood pressur…

This pilot study tested whether a continuous glucose monitor (CGM)-based algorithm helps people with type 2 diabetes adjust their long-acting insulin better than the usual finger-stick method. Thirty adults already on basal insulin used a CGM and followed either the new algorithm…

This study looked at 159 adults with type 2 diabetes to see if the way you start using a continuous glucose monitor (CGM) affects blood sugar control. Researchers compared a nutrition-focused approach versus letting people figure it out on their own. The goal was to see how much …

This study tested a diet low in advanced glycation end products (AGEs) in 36 adults aged 55-65 with type 2 diabetes, coronary artery disease, and overweight. After reducing AGE intake by about 56%, participants saw a 30% drop in a blood marker linked to diabetes complications. Th…

This study tested a smartphone app called T2.coach that gives personalized tips to help people with type 2 diabetes manage their blood sugar. 300 adults with high blood sugar used the app or received standard care for 6 months. The goal was to see if the app could lower blood sug…

This study tested whether two types of intermittent fasting (eating only at certain times or on certain days) can help people with type 2 diabetes control their blood sugar and possibly achieve remission. 57 adults with type 2 diabetes participated in a year-long lifestyle progra…

This study tested a new investigational medicine called CagriSema (a combination of two drugs) in 274 adults with type 2 diabetes who were already taking daily insulin. Participants received either CagriSema or a placebo shot once a week for about a year. The goal was to see if C…

This study tested a 12-week phone program for 60 African American women aged 40-64 with type 2 diabetes and multiple caregiving responsibilities. Participants received either diabetes education or extra support tailored to their caregiving challenges. The goal was to see if the p…

This study tested whether a new investigational medicine called CagriSema (a combination of two drugs) can reduce kidney damage in people with chronic kidney disease, type 2 diabetes, and overweight or obesity. About 626 participants received either CagriSema, one of its componen…

This study tested whether electronic alerts in the emergency department help doctors start diabetes care sooner. 300 adults with high blood sugar were included. The alerts prompted doctors to order additional tests and arrange follow-up appointments. The goal was to see if this l…

This study tested a once-daily oral medication called orforglipron against a placebo in over 1,600 adults who are overweight or have obesity and also have type 2 diabetes. The goal was to see if the drug helps with weight loss and improves blood sugar control. Participants took t…

This study tested a new system that uses a continuous glucose monitor (CGM) to track blood sugar levels in real time for hospitalized patients with high-risk type 2 diabetes. The system sends data to a digital dashboard so a care team can monitor many patients at once and quickly…

This study looked at whether computer analysis of voice recordings can detect type 2 diabetes in adults. Over 7,300 participants recorded themselves reading and answering questions online. A subset also provided blood samples to check accuracy. The goal is to see if voice analysi…

This study tested a special version of the Diabetes Prevention Program made just for men. 301 men with pre-diabetes or high risk took part. The program focused on helping them lose weight through lifestyle changes. Results showed that men who attended more sessions lost more weig…

This study looked at medical records of over 21,000 adults with type 2 diabetes and COPD to see if a class of diabetes drugs called SGLT2 inhibitors could reduce the risk of developing lung cancer compared to another diabetes drug class, sulfonylureas. Researchers analyzed existi…

This study tested a mobile, web-based program called STEPS to see if it could lower the risk of type 2 diabetes in Hispanic adults living in rural areas. 179 participants were randomly assigned to use the STEPS program or receive usual care for three months. Researchers measured …

This study looked at whether telling overweight or obese East Asian adults their genetic risk for type 2 diabetes, combined with using a Fitbit, helps them become more active. About 355 people aged 40-60 took part. Some received only a Fitbit, while others also got their genetic …

This study looked at whether taking daily vitamin D or fish oil supplements can help prevent type 2 diabetes. Over 22,000 adults without diabetes took part. Researchers tracked who developed diabetes over time to see if the supplements made a difference.

This study tested whether using electrical stimulation on the thigh muscles can improve how the body uses insulin in people with type 2 diabetes. 18 adults with type 2 diabetes received a single session and then 6 days of daily stimulation. The goal was to see if this could be an…

This study tested a special diabetes education program for adults with Type 2 diabetes and physical disabilities like spinal cord injury or multiple sclerosis. The program included nutrition advice and self-management skills, delivered in an accessible way. Researchers measured c…

This study tested a mindfulness program for 30 teens aged 12-18 with prediabetes or type 2 diabetes. The goal was to see if the program was practical and liked by participants, and to explore any health benefits like blood sugar control. Teens attended sessions and gave feedback …

This study looked at whether doing simple bodyweight exercises (calisthenics) at home with remote guidance can improve oxygen use, muscle health, and daily activity in adults with type 2 diabetes. Forty participants completed the program, and researchers measured their exercise c…

This study tested a phone-based coaching program for veterans with type 2 diabetes who feel stressed or overwhelmed by daily self-care tasks like checking blood sugar and taking insulin. The program provided personalized support and referrals to help reduce diabetes distress and …

This small study tested whether gummy candies made with maqui berry could help overweight adults control their blood sugar after eating a carb-rich meal. Ten participants ate white bread alone or with the maqui gummies on separate days, and their blood sugar and antioxidant level…

This study tested a mindfulness-based diabetes education program for adults with type 2 diabetes who feel high stress about their condition. 36 participants from low-income clinics were randomly assigned to either the mindfulness program or standard diabetes education. The goal w…

This study looked at whether drinking specialty coffee (rich in a natural compound called chlorogenic acid) could improve memory and thinking in people with type 2 diabetes. Forty adults who already drink coffee took memory and speed tests after drinking either specialty or regul…

This study looked at whether a 6-month exercise program could improve physical abilities, thinking, and quality of life in older adults (ages 60-80) with type 2 diabetes who are also frail. 80 participants were randomly assigned to exercise or usual care. Researchers measured han…

This study tested whether Buerger-Allen exercises, a series of leg movements, can improve blood flow in people with type 2 diabetes. 74 adults aged 35-65 who had been using insulin for at least 5 years took part. The exercise group did the routine plus standard care, while the co…

This study tested a program that used text messages and financial rewards to encourage physical activity in 75 teens and young adults (ages 13-22) with prediabetes or type 2 diabetes. Participants wore a Fitbit and received motivational texts and small incentives to increase thei…

This study looked at whether a game-based education program could lower anxiety and help people with type 2 diabetes follow their insulin treatment better. 72 adults who recently started insulin were split into two groups: one attended four weekly education sessions, and the othe…

This study looked at whether progressive relaxation exercises can help people with type 2 diabetes who have nerve pain, fatigue, and poor sleep. 88 adults took part, and researchers measured changes in pain, tiredness, and sleep quality. The goal was to see if a simple, non-drug …

This study looked at whether a combination of clinical Pilates, nurse coaching, and peer group work could improve general health in older adults with type 2 diabetes. 48 people aged 65 and older took part in one of four groups for 12 weeks. The goal was to see if these activities…

This pilot study tested a mobile app designed to help adults who struggle with binge eating, have type 2 diabetes, and face food insecurity. The goal was to see if the app was easy to use and helpful for managing eating and weight. Thirty-one people took part, and researchers mea…

This study tested a new way of caring for young adults (ages 18-30) with type 1 or type 2 diabetes as they move from pediatric to adult diabetes clinics. 45 participants were split into two groups: one received the new collaborative care model, the other received usual care. Rese…

This study tested a new combination drug called CKD-383 in 31 healthy adults to see how the body absorbs it compared to taking the individual drugs separately. Participants received a single dose of either the combination or the separate drugs, then switched. The goal was to meas…

This early-stage study tested a new combination diabetes drug called CKD-383 in 30 healthy adults. The goal was to see how the drug moves through the body and if it is safe. No treatment for diabetes was given or measured.

This study looked at whether chemicals in the breath (VOCs) can match blood sugar levels in people with type 2 diabetes. Twenty adults with diabetes had their breath analyzed while their blood sugar was changed through glucose drinks, insulin, and a meal. The goal is to see if a …

This study looked at how well 60 adults with type 2 diabetes could follow a Mediterranean diet for 12 months in real-life settings. Researchers measured adherence using a simple questionnaire and checked blood and urine markers. The goal was to find out what makes it hard to stic…

This study checked if a generic version of a diabetes pill (Ertugliflozin/Metformin) works the same as the brand-name drug (Segluromet). 36 healthy adults took a single dose of each pill in random order, and researchers measured drug levels in their blood. The goal was to prove t…

This study looked at 126 people with type 2 diabetes, some with kidney disease (diabetic nephropathy) and some without. Researchers measured three inflammatory markers (NGAL, TNF-α, and IL-10) in both saliva and blood to see how they relate to gum health. The goal was to better u…

This study looked at over 386,000 adults with type 2 diabetes to compare four common second-line medications (GLP-1 agonists, SGLT2 inhibitors, DPP-4 inhibitors, and sulfonylureas) for their effects on heart health and other outcomes. Researchers used existing medical records to …

This study looked at the brain's central clock (the suprachiasmatic nucleus) in 28 people with different stages of insulin resistance, including those with type 2 diabetes. Using advanced MRI scans, researchers measured how the clock responded to light. The goal was to understand…

This study looked at whether replacing sitting time with standing and walking can improve daily blood sugar levels in South Asian adults who are overweight or obese. Eighteen participants changed their daily routines to sit less and move more. The results showed that this simple …

This study aimed to understand why Black older adults with type 2 diabetes spend long periods sitting and how to help them move more. Researchers worked with 33 participants to design practical strategies for breaking up sedentary time. The goal was to improve heart health and bl…

This study tested two ways to improve kidney disease care for Hispanic/Latinx and Black patients with diabetes. First, community groups helped screen people for kidney disease and connect them to a primary care doctor. Second, clinics got support to help doctors screen and treat …

This study looked at over 450,000 adults with obesity and type 2 diabetes who were already taking a GLP-1 or SGLT2 drug. Researchers compared what happened when they added another diabetes medicine early (within 90 days) versus not adding one. The goal was to see if early add-on …

This study looked at 110 adults with type 2 diabetes to compare two easy methods of measuring hidden belly fat: a simple waist measurement and a device that uses a mild electrical current (bioelectric impedance). The goal was to see which method better predicts heart disease risk…

This study tested how different types of meals before exercise affect blood sugar levels in men with type 2 diabetes. Fifteen participants completed several sessions: fasting or eating a meal rich in glucose, fructose, fat, or aspartame, followed by one hour of exercise. The goal…

This small pilot study looked at whether aprepitant, a drug used for nausea from chemotherapy, can change levels of aldosterone (a hormone that affects blood pressure) in people with type 2 diabetes and high blood pressure. Five participants took either aprepitant or a placebo fo…

This completed study looked at whether information from everyday healthcare claims can accurately predict the results of a large clinical trial (SURPASS-CVOT) that compared two diabetes drugs, tirzepatide and dulaglutide, for heart safety. Researchers analyzed records from over 4…

This study looked at how brown adipose tissue (brown fat) works in people with type 2 diabetes. Researchers used special PET scans with a fat-based tracer to get a more accurate picture of brown fat activity. The goal was to better understand brown fat's role in metabolism, not t…

This study looked at how the drug HRS9531 enters and leaves the body in people with different levels of kidney function. Researchers compared 32 adults with normal kidneys to those with mild or moderate kidney impairment. The goal was to understand if kidney problems change how t…

This study looked at over 16,500 adults with chronic heart failure who were part of a national remote monitoring program in France. Researchers wanted to see how having diabetes, other health conditions, and short-term weight changes were linked to how long patients lived. No new…

This early-stage study tested a new experimental drug called CKD-383 in 30 healthy adults. The goal was to see how the drug moves through the body and if it is safe. Participants received a single dose of the drug and had their blood levels measured. This study does not test if t…

This early-stage study tested a new experimental drug, NNC0113-6856, in 70 healthy men to see if it is safe and how it moves through the body. Participants received either a single oral dose or an injection into the vein. The goal was to gather initial safety data and measure dru…

This study looked at whether a person's psychological profile (type A or B personality) is linked to foot wounds in type 2 diabetes. Researchers compared 66 adults with diabetes—some with foot wounds, some without—using a simple questionnaire. The goal was to understand how perso…

This study looked at insurance claims from 70,000 people with type 2 diabetes and heart disease to compare two drugs, tirzepatide and dulaglutide, on their risk of heart attack, stroke, or death. The goal was to see if real-world data could mimic a large clinical trial. No new tr…

This study looked at how an 8-week personalized exercise program affects heart and blood vessel function in 59 men with obesity or type 2 diabetes. Participants were compared to healthy volunteers, both trained and untrained. The goal was to see if exercise can improve cardiovasc…

This study looked at 500 women who had gestational diabetes during pregnancy. It checked how many had abnormal blood sugar (like type 2 diabetes or prediabetes) 4 to 12 weeks after giving birth. The goal was to see if the timing of their gestational diabetes diagnosis (before or …

This study tested how easy and acceptable the P-STEP mobile app is for people with chronic conditions like asthma, COPD, heart disease, or type 2 diabetes. 178 adults in Leicester, UK, used the app for 12 weeks and gave feedback on its usability. The goal was to see if the app is…

This study looked at how different exercise intensities change gut bacteria in people with type 2 diabetes. 40 adults were randomly assigned to 16 weeks of moderate or high-intensity exercise. Researchers compared changes in blood sugar and gut microbiome diversity between the tw…

This study looked at whether shared medical appointments are a good way to care for young people with type 2 diabetes. Researchers designed four group activities about nutrition, exercise, stress, and peer support, and planned a clinic workflow. About 53 teens and their caregiver…

This study tested whether a single MRI scan can reliably measure body composition and the health of multiple organs (like the liver, heart, and kidneys) in one session. It included 43 adults—some with Type 2 Diabetes and some healthy volunteers. The goal was to see if the scan gi…

This completed study looked at how different patterns of body fat—too much, too little, or unevenly distributed—affect insulin resistance and the immune system. Researchers measured various immune markers, especially interleukin-7, in 126 adults with obesity, lipodystrophy, or ty…

This study looked at health records from over 887,000 people with type 2 diabetes and overweight to compare two drugs—tirzepatide and semaglutide—for preventing heart attacks, strokes, or death. The goal was not to test a new treatment but to see if analyzing real-world data can …

This study aims to understand why dapagliflozin, a diabetes medication, can increase bad cholesterol levels in people with type 2 diabetes. Researchers will track how the body produces and removes cholesterol in 28 patients over 6 months. The findings could help doctors choose th…

This study tested whether a smartwatch could help identify digital signs of type 2 diabetes. Researchers gave 210 adults a special watch to track health data like activity and heart signals. They used artificial intelligence to find patterns linked to diabetes. The goal was to im…