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Fasting your way to better blood sugar? new study tests two diet plans

NCT ID NCT05860413

Disease control Sponsor: University of Kansas Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether two types of intermittent fasting—eating very little a few days a week or eating only during an 8-hour window—can help people with type 2 diabetes improve their blood sugar control. Fifty-seven adults with diabetes followed one of these diet plans for a year. The goal was to see if the diets were practical and could potentially lead to diabetes remission.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Intermittent fasting (two types: intermittent energy restriction and time-restricted eating)
What this could lead to
If successful, this could point toward a non-drug way to manage or even reverse type 2 diabetes through diet timing.
What could go wrong
This is a small, early feasibility study with only 57 participants, so results may not apply to everyone. Fasting can be hard to stick with long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

57 people

The number who actually took part.

Started

Jan 2023

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Diagnosed with type 2 diabetes in the past 10 years. 2. Age 21-65 years 3. BMI of 25 - 45 kg/m2 4. HbA1c of 6.7-9.5%, or those with A1c of \<6.7% on glucose-lowering medications 5. Ability to participate in a graduated physical activity program 6. Clearance from study physician. Exclusion Criteria: 1. Inability to attend health education meetings. 2. Weight change of \>=5% in the previous 3 months. 3. Addition of new antihyperglycemic or weight-reducing medication in the previous 2 months. 4. Serious medical risk such as ongoing treatment for cancer, uncontrolled hypertension, recent cardiac event, or other medical condition presenting acute risk of participation in a lifestyle change program. 5. Untreated depression or anxiety, or increase in associated medications in the previous 3 months. 6. Current participation in another lifestyle change intervention, such as a tobacco cessation program or physical activity program. 7. Pregnancy or lactation within the previous six months 8. Weight of \>450 lbs 9. Currently taking medications that may result in hypoglycemia during fasting and unwilling to stop prior to the study

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Type 2 diabetes

Contacts and locations

Locations

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.