University Of Alabama At Birmingham

This study is testing whether pirfenidone, a drug already approved for a lung disease, can help people who suffer from repeated, painful episodes of acute pancreatitis. The goal is to see if taking the drug for six months can reduce the number of future attacks, lower inflammatio…

This study aims to find the best oxygen level for premature babies who have developed a severe chronic lung disease (bronchopulmonary dysplasia) and high blood pressure in their lungs (pulmonary hypertension). Doctors will test two different oxygen level targets in 39 infants to …

This study aims to find the best amount of human milk to feed very premature babies to help them grow well and keep their guts healthy. Researchers will compare two different feeding volumes (140-160 mL/kg/day vs. 180-200 mL/kg/day) in about 486 infants born between 27 and 31 wee…

This study is testing whether a ketogenic (keto) diet helps people maintain weight loss better than a low-fat diet. Researchers want to see if the keto diet helps the body burn more calories and reduces hunger after weight loss. The study involves 20 adults with obesity who will …

This study is testing whether changing when a key drug is given can better prevent a serious complication called graft-versus-host disease (GVHD) after a stem cell transplant for blood cancers. It will enroll about 29 adults with leukemia or related disorders who are receiving a …

This study tests a personalized approach for treating newly diagnosed multiple myeloma, a blood cancer. It uses ultra-sensitive testing to detect tiny amounts of remaining cancer cells after initial treatment. Based on these results, patients receive different follow-up treatment…

This study is testing a new combination of chemotherapy and a targeted drug called mirvetuximab soravtansine for patients with advanced ovarian, fallopian tube, or primary peritoneal cancer. The goal is to see if giving this treatment before surgery is safe and effective at shrin…

This study is testing a lower, daily dose of the cancer pill capecitabine for people with advanced breast cancer who are 60 or older, or who are frail at any age. The goal is to see if this gentler dose can still help control the cancer while being easier for these patients to to…

This study is testing a multi-step treatment plan for people newly diagnosed with advanced ovarian cancer. It combines standard chemotherapy with an immunotherapy drug before surgery, followed by a targeted therapy pill and immunotherapy as long-term maintenance. The main goal is…

This study is testing if using two different immune-boosting drugs together with chemotherapy works better than the current standard of one immune drug plus chemo. It focuses on patients with advanced non-small cell lung cancer whose tumors lack a specific marker called PD-L1. Re…

This trial is testing whether intravenous immunoglobulin (IVIG) can help control anti-HMGCR immune-mediated necrotizing myopathy, a rare autoimmune disease where the immune system attacks muscle tissue. Twelve participants with active disease will receive either IVIG or a placebo…

This study is testing if adding a natural growth factor to a standard bone graft helps grow jawbone better for dental implants. It will compare the growth factor method against the standard method in 44 adults who need implants but don't have enough bone. Researchers will measure…

This study is testing whether adding a special play activity using finger puppets to standard developmental care helps improve development in babies born prematurely. Researchers will compare babies who receive the puppet-based training with their caregivers to those who receive …

This study is testing if wearing special soft contact lenses daily can slow down the worsening of nearsightedness in children. Researchers will compare two types of lenses over one year to see if they can control excessive eye growth, which is linked to future eye health risks. T…

This study is testing a talk therapy program called ReACT for teens who have seizures not caused by epilepsy. The goal is to see if helping teens feel more in control of their body and less fearful of symptoms can reduce how often the seizures happen. Teens aged 11-18 will attend…

This study is testing if keeping patients with severe lung failure (ARDS) in an upright position in bed helps them breathe better while on a ventilator. It will compare this upright positioning to the standard practice of just raising the head of the bed. The goal is to see if th…

This study is a first step to see if a larger trial can be done to compare two different talk therapy programs for teens with functional seizures. It will test if it's possible to recruit enough teens, keep them in the study, and deliver the therapies correctly. The goal is to ga…

This study is testing whether a low-carbohydrate diet can help teenagers with type 2 diabetes better control their blood sugar and improve their body's response to insulin. Over 24 weeks, 40 participants aged 12-18 will follow either a low-carb diet or the standard diabetes diet …

This study is testing a much shorter radiation schedule for women with early-stage breast cancer. After a lumpectomy, participants receive just 5 concentrated radiation treatments instead of the standard longer course. The main goal is to see if this shorter approach is safe and …

This study is testing whether blocking a kidney tumor's blood supply before freezing it makes the treatment safer and more effective. Researchers are enrolling 25 adults with medium-sized kidney cancer (4-7cm) that hasn't spread. The goal is to see if this two-step procedure help…

This study tests a follow-up program for people who visit the emergency room for painful gout attacks. Researchers will use patient navigators—trained community members—to help patients schedule doctor appointments and manage their gout better. The goal is to improve long-term ca…

This study is testing whether carefully lowering blood pressure in pregnant women with preeclampsia or gestational hypertension can safely extend the pregnancy. Researchers want to see if keeping blood pressure below 140/90 mmHg allows babies more time to develop before delivery.…

This study is testing whether the antibiotic azithromycin can help children under 2 years old who are hospitalized in intensive care with severe RSV lung infections. Researchers want to see if the medicine helps kids breathe easier and get out of the hospital and ICU sooner. The …

This study tests whether using a smaller radiation margin (0mm) works as well as the standard larger margin (2mm) for treating brain tumors that have spread from other cancers. Researchers want to see if the smaller margin can control the tumors just as effectively while causing …

This study is testing a personalized approach to treatment after surgery for kidney cancer. It uses a special blood test to look for tiny traces of leftover cancer. Patients who test negative for this 'molecular residual disease' will skip standard follow-up drug treatment, while…

This study is testing if changing *when* you eat, not *what* you eat, can improve heart health in older adults with high blood pressure. Researchers are enrolling 30 people aged 60+ who typically eat over a 12-hour window. The goal is to see if eating all meals within an 8-hour w…

This study is testing whether changing the timing of a standard immune-suppressing drug (ATG) can better prevent severe graft-versus-host disease (GVHD) after a stem cell transplant. The trial will enroll 56 adults with acute leukemia, myelodysplastic syndrome, or myeloproliferat…

This study is testing if a 4-month, online strength training program is practical and helpful for Black women at risk for heart disease and diabetes. It will enroll 36 women who do not currently do regular strength training. The main goal is to see if the program is easy to follo…

This study is testing a 24-week church-based program called FELLAship, designed to help Black men at risk for heart disease, diabetes, and obesity improve their health. Participants attend weekly sessions for exercise and health education, receive personal support, and track thei…

This study is testing a new behavioral training program designed to help people quit smoking. It focuses on teaching smokers how to manage the negative emotions and cravings that often lead to relapse. The study will enroll 400 adult smokers who want to quit and compare different…

This study is testing whether telling people their genetic risk for high blood pressure helps them manage it better. Researchers will enroll 300 adults aged 18-55 who already have high blood pressure and poor heart health. Half will receive their genetic risk score and counseling…

This study is testing three types of custom-made stent grafts to treat dangerous bulges or tears in the body's main artery (the aorta) near vital branches to organs and the brain. The goal is to see if these less invasive, tube-like devices can safely repair these complex areas, …

This early-stage study is exploring whether stem cells created from a patient's own blood can repair damaged blood vessels in the eyes of people with diabetic retinopathy. Researchers will grow special 'repair cells' in the lab and test them in animal eyes first. The goal is to d…

This study is testing whether adding a new dental gel to the standard deep cleaning treatment works better for adults with moderate gum disease. The gel is used daily at home and aims to reduce deep pockets around the gums more than the standard treatment alone. Researchers will …

This study is testing a new combination treatment for aggressive brain cancers like glioblastoma. It combines a genetically engineered virus designed to attack cancer cells with an immunotherapy drug that helps the immune system fight the tumor. The trial aims to find a safe and …

This study is testing whether specific computer-based brain training exercises can help older adults with mild memory problems maintain their ability to perform daily tasks and delay the onset of dementia. Researchers will compare four different combinations of training exercises…

This study is testing whether daily morning bright light therapy can help people recovering from opioid addiction. Researchers want to see if this simple, non-drug treatment improves sleep patterns and reduces drug cravings. About 105 participants receiving standard medication tr…

This study is testing a talk therapy called ReACT for teens (ages 11-18) who have non-epileptic seizures. These seizures are real and distressing but are not caused by abnormal brain electricity like epilepsy. The goal is to see if therapy that helps teens feel more in control an…

This study is testing a 24-week lifestyle program called Inspire HER, designed specifically for Black women at risk for heart disease. The program provides health education, physical activity guidance, and social support resources. Researchers will compare the program's effective…

This study is testing whether patients with newly diagnosed multiple myeloma or amyloidosis can safely delay or avoid stem cell transplant. Researchers will use a sensitive blood test to measure how well patients respond to initial drug therapy. If patients show a very deep respo…

This study is testing whether a drug that activates a protein called LXR can help prevent or slow diabetic retinopathy, a common eye complication of diabetes. Researchers believe the drug works by improving how the body handles cholesterol and reducing harmful inflammation in the…

This study aims to find the best time to place a small mesh sling that supports the bladder during a robotic surgery that repairs pelvic organ prolapse. Researchers are comparing whether placing the sling before or after the main repair leads to better control of urine leakage, f…

This study aims to find the best combination of support methods to help people maintain weight loss after they've lost weight. Researchers will test four different approaches—including limiting food variety, home exercises, buddy support, and coping workshops—in various combinati…

This early-stage trial is testing if adding two anti-cancer drugs, decitabine and venetoclax, to a standard stem cell transplant procedure is safe for adults with high-risk blood cancers like acute myeloid leukemia (AML). The main goal is to find the safest dose and see if this c…

This early-stage study is testing the safety and best dose of an oral medication called tazemetostat for adults with peripheral T-cell lymphoma that has returned or not responded to prior treatment. The drug is already approved for a different type of lymphoma. Researchers will e…

This study tests whether connecting patients who recently broke a bone due to osteoporosis with a bone health specialist through a patient navigator helps prevent future fractures better than standard education. It involves over 2,600 adults aged 50+ who have had a fragility frac…

This study is testing a bundled support program designed to help people with opioid addiction continue their treatment after leaving the emergency room. The program combines telehealth check-ins, peer support specialists, medication (buprenorphine), and help connecting to ongoing…

This study is testing whether a new type of brain scan can better detect remaining cancer in patients with high-grade glioma after they finish radiation therapy. Researchers will use two special PET/MRI scans on about 20 patients to see if they can spot active tumor cells that re…

This study is testing whether a special type of ultrasound can detect kidney injury earlier in patients who have had vascular surgery. Researchers will compare scans from 50 healthy people to scans from patients who develop kidney problems after their operation. The goal is to se…

This study is testing whether a simple tampon sample can be used to find early signs of uterine or ovarian cancer. Researchers are enrolling 1,500 women who are already scheduled for surgery to remove their uterus or ovaries. They will compare DNA markers found in the tampon samp…

This study is testing a special fluorescent dye called panitumumab-IRDye800. It is given to patients before surgery to see if it makes cancer cells glow under a special camera, helping surgeons better see and remove all the cancer. The goal is to improve the accuracy of surgery f…

This study is testing a new version of a tiny marker that doctors place during breast biopsies. Researchers want to see if surgeons can find and remove the new marker more easily during surgery compared to the older version. The study will also ask surgeons how satisfied they are…

This study aims to test an artificial intelligence (AI) eye screening program in community health centers that serve low-income and uninsured patients. It will screen 1,800 adults at risk for glaucoma, diabetic retinopathy, cataracts, or vision problems to see if the program effe…

This is a small, early-stage study to see if a new type of imaging scan can more accurately find and measure head and neck cancer tumors before surgery. Researchers will compare a new scan using a special tracer to the standard scan patients already receive. The goal is to improv…

This small, early-stage study is testing a new type of PET scan to see if it can predict which patients with a specific type of breast cancer (HER2-positive) will respond well to targeted therapy drugs. Researchers will give participants a special imaging tracer and use a combine…

This study is testing whether an augmented reality headset can help medical providers place IVs and other catheters more successfully. Researchers will see if the technology helps doctors get access to a patient's vein on the first try and reduces the time it takes. The study wil…

This study is testing a new way to help diagnose biliary atresia, a serious liver disease in newborns. Doctors give babies a safe, fluorescent dye and then check their diapers with a special camera to see if bile is flowing normally. The goal is to see if this simple test can acc…

This study is testing if sending high-risk babies home from the NICU with a special sock that monitors their oxygen levels can help prevent emergency room visits and hospital readmissions. About 700 infants who no longer need breathing support will be randomly assigned to either …

This study is testing if a medication called misoprostol can help doctors get a better view of the cervix during cancer screening exams. It will involve 420 women who have a cervix that is difficult to examine fully. Participants will be randomly assigned to receive either the st…

This study is testing a new clinic-based program designed to help more Black and Latinx adults with autoimmune rheumatic diseases get the updated COVID-19 vaccine. Researchers want to see if providing better information and addressing access issues can increase vaccination rates …

This study is testing a personalized approach to help people with prediabetes and disabilities lose weight to prevent type 2 diabetes. It starts participants on either a high or low-carb diet, then adjusts their plan after 4 weeks if they aren't losing enough weight. The goal is …

This study is testing if letting mothers and their low-birth-weight babies stay together for extended skin-to-skin care after leaving intensive care can help prevent depression in the mothers. It will involve over 1,900 mothers and babies in Zambia, comparing a few days of this c…

This study is testing if giving the drug selumetinib early can prevent dangerous, non-cancerous nerve tumors from growing and causing serious problems like blindness or nerve damage in young children with neurofibromatosis type 1 (NF1). It will enroll up to 200 children aged 1 to…

This study aims to see if teaching patients how to use crutches, walkers, or knee scooters before their foot or ankle surgery helps prevent falls during recovery. It will involve 250 adults who are scheduled for this type of surgery and will need to avoid putting weight on their …

This study is testing whether following a healthy DASH-style diet for one week can lower the risk of forming new kidney stones. Researchers will provide all meals to 48 adults who have had kidney stones before. They will compare urine test results from people on the healthy diet …

This study is testing whether a 6-week online program teaching magic tricks can help improve social skills and emotional well-being in teenagers with autism. Researchers will compare 60 adolescents who take the virtual magic classes to a waitlist group. The goal is to see if lear…

This study is testing whether a personalized exercise program using video games can help people manage common side effects after head and neck cancer treatment. Researchers will enroll 150 people who have finished treatment and are struggling with fatigue or pain. One group will …

This study is testing whether a 4-month supervised exercise program can help improve memory and thinking skills in older adults living with HIV. Researchers will compare high-intensity interval training to moderate continuous exercise in 110 sedentary participants. The goal is to…

This study is testing a telehealth program called C-READY, designed to help teenagers with sickle cell disease build the skills they need to manage their own healthcare as they become adults. Over 120 teens will participate in one-on-one video sessions with a therapist to learn a…

This study is testing a community-based program designed to help cancer survivors and their support people living in persistent poverty areas improve their health. The program focuses on adapting healthy eating and physical activity approaches to fit the specific challenges these…

This study is testing a training program designed to help patients with advanced chronic kidney disease and their caregivers make health decisions together more effectively. The program, delivered remotely by a coach, teaches communication and support skills. Researchers are comp…

This study is testing a personalized, 32-week online exercise program to help people with mobility disabilities become more physically active. Researchers are using a smart trial design to see if adding health coaching calls or live group training helps participants stick with th…

This study is testing a type of talk therapy to see if it helps improve mental health for men who are HIV-positive. It will involve 24 participants and focuses on reducing symptoms of stress, anxiety, and depression. The goal is to see if this therapy is practical and effective f…

This study is testing whether using carbon dioxide gas instead of regular air during endoscopy procedures causes less abdominal pain, bloating, and gas in children afterward. Researchers will compare the two gases in 350 children aged 6 months to 18 years who are having various t…

This study is testing a 12-week program designed to help women over 40 who are living with both HIV and high blood pressure. The program combines personalized exercise plans, support from a peer, and home blood pressure monitoring. Researchers want to see if this approach is prac…

This study tests whether having cancer patients report symptoms from home using a digital system helps them feel better and reduces hospital visits. Patient navigators will help 7500 adults receiving cancer treatment use weekly symptom check-ins. The goal is to see if this real-w…

This study is testing if having a specially trained, calm therapy dog present can help reduce pain and anxiety for children aged 3 to 10 who are having surgical pins removed from their elbow. The pin removal is a quick clinic procedure that can be uncomfortable and scary for kids…

This early-stage study is exploring whether a guided session with the psychedelic compound psilocybin can help reduce pain, fatigue, and other symptoms for women with fibromyalgia. Researchers will compare psilocybin against an active placebo drug in about 30 participants. The go…

This study is testing whether a mobile brain-training app can help reduce 'chemo brain'—the memory and thinking problems many people experience during cancer treatment. It will involve 64 women with gynecologic cancers who are undergoing chemotherapy. The goal is to see if regula…

This study is testing a new program that provides legal help to cancer patients. It aims to see if helping patients with issues like insurance denials, disability benefits, and employment rules is practical and can reduce their stress and improve their quality of life. The progra…

This study is testing whether offering financial counseling as a standard part of cancer care helps patients. Researchers will look at data from 40 patients and staff to see if this counseling reduces money stress, improves quality of life, and lessens emotional distress for peop…

This study is testing whether a 10-week online writing program, guided by a coach, can help adults with spinal cord injury cope with grief and emotional distress. Researchers will enroll 60 participants to see if writing about their feelings reduces grief, stress, and depression …

This study is testing whether a specific type of talk therapy can help people with obsessive-compulsive disorder (OCD) that centers on religious thoughts and behaviors. It will involve 10 adult participants who experience this specific form of OCD. The main goal is to see if the …

This study is testing whether two specific diet plans, followed by a period of calorie restriction for weight loss, can improve daily life for people with multiple sclerosis. One hundred adults with MS will follow either a low-glycemic or standard diet for 32 weeks, with free gro…

This small pilot study is testing an intensive physical therapy program for adults who have had a stroke and still have mild weakness in their more-affected arm. The therapy involves daily training sessions where participants practice specific arm and hand movements while their s…

This study is testing if a special diet drink and online brain games can help blood cancer survivors who are struggling with memory and thinking. For 12 weeks, one group will use both the diet drink and the games, while another group waits. Researchers want to see if this combina…

This study aims to understand how sepsis survivors recover their physical strength after leaving the hospital. Researchers will follow 40 patients who needed intensive care for sepsis, tracking their physical function over time to identify different recovery patterns. The goal is…

This study aims to find out if pumping breast milk more often helps mothers of preterm babies produce more milk. Researchers will compare mothers who pump every 2 hours with those who pump every 3 hours during their baby's first month. The goal is to learn which schedule leads to…

This study uses special brain scans to measure and map a harmful protein called tau in people with Alzheimer's disease. Researchers will scan 160 participants already enrolled in an ongoing Alzheimer's research program to see how tau buildup relates to race, heart health risks, a…

This study is creating a collection of health information and DNA samples from 500 adults to help researchers better understand heart disease, high blood pressure, diabetes, and obesity. Participants provide their health data and biological samples, which will be stored for futur…

This study aims to understand if childhood trauma increases suicide risk by looking for biological markers in the blood. Researchers will enroll 450 adults with depression or no mental illness to analyze genetic material and stress responses. The goal is to identify potential bio…

This study aims to understand how glaucoma affects older adults' ability to move around and participate in activities outside their home. Researchers will compare 100 people with glaucoma to those with healthy vision, focusing on how well they see in dim lighting. The goal is to …

This study aims to compare two different surgical techniques used during corrective jaw surgery. Researchers want to see if using a specific type of saw during the procedure leads to a better pattern of bone breakage and healing. They will enroll 40 patients undergoing jaw surger…

This study aims to understand how severe kidney injury is treated and what happens to patients across different Latin American countries. Researchers will observe 1,000 critically ill adults who need dialysis for sudden kidney failure. The goal is to collect data on current care …

This study is testing a new data dashboard designed to help clinics in Alabama better track and improve their HIV prevention services. It will collect real-time information from seven clinics to identify where services are lacking and to help ensure PrEP, a preventive medication,…

This study is creating a large registry to track the health of older adults (age 50+) with blood cancers like multiple myeloma. Researchers will collect information through questionnaires and simple physical tests to understand how frailty and aging affect these patients. The goa…

This study aims to understand how the brain processes sensory information in people with Parkinson's disease. Researchers will record brain activity from 30 participants (both healthy individuals and Parkinson's patients) during deep brain stimulation surgery while they perform s…

This study aims to understand if a partial deficiency in a protein called CFTR contributes to chronic sinusitis. Researchers will measure electrical signals in the noses of 20 participants (both healthy individuals and those with sinusitis) to assess how well this protein is work…

This study aims to understand how spinal cord stimulators affect the brain and nerves in people with restless legs syndrome (RLS). Researchers will measure brain activity and nerve responses in 50 participants, including people with RLS who have or will receive a stimulator, and …

This study is testing whether a single dose of a ketone supplement drink can improve thinking skills, vision, and driving performance in healthy adults. Researchers are comparing three groups: people who are obese and inactive, lean and inactive people, and lean, active athletes.…

This study aims to understand if a common liver condition (MASLD) changes how much oxalate the body makes on its own. Oxalate is a natural substance that, in high amounts, can contribute to kidney stones. Researchers will measure this by having 28 participants follow a special lo…

This study aims to understand if providing community-based breastfeeding support to mothers of infants with sickle cell disease can improve health outcomes. Researchers will compare 20 mother-infant pairs, with some receiving support and others being observed. They will track how…

This study aims to see if a special coaching program for parents, focused on early literacy and numeracy activities, helps improve infant learning and development scores by age 2. It involves 188 families with healthy, full-term or late preterm babies. Half the parents receive th…

This study aims to understand and improve survival for lymphoma patients who develop a severe, life-threatening immune system complication called HLH. Researchers will look back at the medical records of up to 2,000 patients to see which treatments and other factors were linked t…

This study aims to understand how preeclampsia, a serious pregnancy complication, might lead to future heart problems. Researchers will collect blood and tissue samples from 64 pregnant women, some with preeclampsia and some without, to study tiny particles called exosomes. By an…

This small pilot study is testing whether a telemedicine support program is practical and helpful for people in Alabama who are living with HIV and also dealing with opioid or stimulant addiction. The goal is to see if remote healthcare visits can help connect this group to neede…

This study aims to understand if people with a specific genetic form of Alpha-1 Antitrypsin Deficiency (AATD) also have variations in nearby genes that weaken their immune system and lead to more lung infections. Researchers will compare the immune response to a pneumonia vaccine…

This study uses special brain scans to measure inflammation in people with early or pre-symptomatic Parkinson's disease. Researchers will follow 60 participants for two years to see how brain inflammation changes over time. The goal is to better understand Parkinson's progression…

This study aims to understand how the brain processes language. Researchers will observe brain activity in adults with epilepsy who already have monitoring electrodes implanted for their medical care. Participants will read or listen to sentences while their brain signals are rec…

This study aims to understand how different types of FDA-approved seasonal flu vaccines affect the body's immune response, specifically the antibodies and cells that fight the flu. Researchers will compare these responses in two groups: healthy adults aged 18-50 and adults aged 6…

This study aims to understand if brain inflammation is linked to chronic pain and fatigue in conditions like fibromyalgia, chronic fatigue syndrome, and multiple sclerosis. Researchers will use a special brain scan to measure inflammation levels in 120 participants, comparing peo…

This study aims to understand how gender identity and hormone levels influence a person's sensitivity to pain. Researchers will recruit 120 cisgender and transgender participants to undergo standardized pain tests (like pressure, heat, and cold) and provide blood samples to measu…

This study is testing whether a special type of PET/MRI scan can help doctors see how well immunotherapy is working for patients with triple negative breast cancer. It will enroll 20 patients who are already scheduled to receive immunotherapy. The scans are for research only and …

This small pilot study aims to see if eating herbs and spices with a potato meal changes how much your blood sugar rises afterward. Researchers will give 10 participants three different potato meals to eat over 10 days and track their blood sugar using a wearable monitor. The goa…

This study aims to understand how brain activity is linked to non-motor symptoms in Parkinson's disease, like depression and thinking problems. Researchers will record brain activity from 140 participants during their routine deep brain stimulation surgery while they perform simp…

This study aims to better understand how Deep Brain Stimulation (DBS) affects brain activity in people with Parkinson's disease. Researchers will record brain signals during surgery to create detailed maps that might help doctors place electrodes more precisely and program the de…

This study aims to understand how the body's natural breakdown of vitamin C contributes to a substance in urine that can form kidney stones. Researchers will feed participants a special diet and give them a safe, traceable form of vitamin C to measure its effects. The goal is to …

This study uses special brain scans (PET and MRI) to measure amyloid plaques in people with and without Alzheimer's disease. Researchers want to understand how these plaques, along with a person's race and heart health factors, relate to memory and thinking problems. The study is…

This study aims to understand how the brain adapts when people lose their central vision due to macular degeneration. Researchers will compare different vision training methods in 60 participants to see how they improve daily tasks and change brain activity. The goal is to gather…

This study aims to understand how the brain processes and controls emotions like fear and anxiety. Researchers will use mild electrical stimulation and recordings in 30 epilepsy patients who already have electrodes implanted for their medical care. The goal is to map brain circui…

This study aims to understand if brain inflammation is causing the neurological symptoms of Long COVID, such as brain fog and fatigue. Researchers will use a special type of brain scan (PET scan) to compare brain activity in 60 people with Long COVID to healthy volunteers. The go…

This study aims to understand how the community of bacteria in the gut changes during the first year after a spinal cord injury. Researchers will follow 35 people with recent injuries, collecting stool and blood samples to see how these changes relate to metabolism and bowel func…