New stem cell filter aims to prevent deadly transplant complication

NCT ID NCT06047886

First seen Apr 17, 2026 · Last updated May 13, 2026 · Updated 4 times

Summary

This study tests a new automated method to select specific stem cells (CD34+) for patients with blood cancers who need a stem cell boost or second transplant. The goal is to lower the risk of graft-versus-host disease (GVHD), a serious complication where donor cells attack the patient's body. About 50 adults with cancers like AML, ALL, or myelodysplastic syndromes will receive the specially processed cells. Researchers will check if this method keeps severe GVHD rates below 25% and improves blood counts without long-term immune-suppressing drugs.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294-3300, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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