New therapy aims to retrain the brain in kids with Seizure-Like episodes
NCT ID NCT05096273
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests a new cognitive behavioral therapy called ReACT for children aged 9-18 with psychogenic non-epileptic seizures (PNES) — episodes that look like seizures but have no physical cause. The therapy focuses on helping kids feel more in control and less afraid of their symptoms. Over 12 sessions, researchers will measure changes in sense of control, pain tolerance, and seizure frequency, with follow-ups up to a year later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Retraining and Control Therapy (ReACT) - a cognitive behavioral therapy
What this could lead to
If it works, this could provide an effective behavioral treatment to reduce seizures and improve quality of life for children with PNES.
What could go wrong
This is a small, early-stage study with only 68 participants, so results may not apply to everyone. The therapy requires active participation and may not work for all children.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sparks Center Office of Psychiatric Research
RECRUITINGBirmingham, Alabama, 35294, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••