Could a new toothpaste help treat gum disease?

NCT ID NCT05384132

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special dental gel (Livfresh) can improve gum health when used alongside standard deep cleaning. About 76 adults with moderate gum disease will brush with the gel twice daily for 6 months. Researchers will measure changes in gum pocket depth and bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Livfresh Dental Gel (test toothpaste)

What this could lead to

If it works, this gel could become a simple at-home addition to standard gum disease treatment, helping reduce deep gum pockets and improve oral health.

What could go wrong

This is a small, early-stage trial with only 76 people. The gel may not provide extra benefit over standard care, and results may not apply to everyone with gum disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PERIODONTAL DISEASES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Dental Plaque gingival disorder Gingival Hemorrhage Gingival Pocket gingivitis periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Unversity of Alabama at Birmingham, School of Dentistry

    RECRUITING

    Birmingham, Alabama, 35294-0007, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••