Could a new toothpaste help treat gum disease?
NCT ID NCT05384132
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a special dental gel (Livfresh) can improve gum health when used alongside standard deep cleaning. About 76 adults with moderate gum disease will brush with the gel twice daily for 6 months. Researchers will measure changes in gum pocket depth and bleeding.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Livfresh Dental Gel (test toothpaste)
- What this could lead to
- If it works, this gel could become a simple at-home addition to standard gum disease treatment, helping reduce deep gum pockets and improve oral health.
- What could go wrong
- This is a small, early-stage trial with only 76 people. The gel may not provide extra benefit over standard care, and results may not apply to everyone with gum disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Unversity of Alabama at Birmingham, School of Dentistry
RECRUITINGBirmingham, Alabama, 35294-0007, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a gentler Deep-Clean beat standard gum therapy?
- Could a toothpaste ingredient reshape the microbes behind gum disease?