Could treating mild hypertension in pregnancy help babies?

NCT ID NCT05989581

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether treating mild high blood pressure (stage 1 hypertension) during pregnancy can improve baby birth weight. 74 pregnant people with blood pressure between 130-139/80-89 mmHg will be randomly assigned to either active treatment with blood pressure medication (labetalol or nifedipine) or usual care. The goal is to see if keeping blood pressure below 130/80 mmHg leads to healthier birth weights.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Labetalol or Nifedipine (blood pressure medication)

What this could lead to

If successful, this could lead to better outcomes for pregnant people with mild hypertension and their babies, potentially informing a larger study.

What could go wrong

This is a very early, small pilot study with only 74 participants. It may not show a clear benefit, and results may not apply to all pregnant people.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypertension, pregnancy-induced

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • UAB

    RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••