Could treating mild hypertension in pregnancy help babies?

NCT ID NCT05989581

Recruiting now Disease control Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times

Summary

This study tests whether treating mild high blood pressure (stage 1 hypertension) during pregnancy can improve baby birth weight. 74 pregnant people with blood pressure between 130-139/80-89 mmHg will be randomly assigned to either active treatment with blood pressure medication (labetalol or nifedipine) or usual care. The goal is to see if keeping blood pressure below 130/80 mmHg leads to healthier birth weights.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Labetalol or Nifedipine (blood pressure medication)
What this could lead to: If successful, this could lead to better outcomes for pregnant people with mild hypertension and their babies, potentially informing a larger study.
What could go wrong: This is a very early, small pilot study with only 74 participants. It may not show a clear benefit, and results may not apply to all pregnant people.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypertension, pregnancy-induced

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION IN PREGNANCY

Contacts and locations

Locations

UAB
RECRUITING

Birmingham, Alabama, 35294, United States

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