University Of Alabama At Birmingham
Clinical trials sponsored by University Of Alabama At Birmingham, explained in plain language.
-
Glow-in-the-dark dye could help surgeons save tiny glands during thyroid surgery
Disease control TerminatedThis study tested whether a fluorescent dye called indocyanine green can help surgeons find and protect the parathyroid glands during thyroid or parathyroid surgery. The dye is injected into the bloodstream and makes the glands glow under a special camera. The trial enrolled 417 …
Phase: PHASE4 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
-
Early trial of tazemetostat for tough T-Cell lymphoma halted after just 6 patients
Disease control TerminatedThis early-phase study tested the safety of a drug called tazemetostat in people with a type of blood cancer called peripheral T-cell lymphoma that had returned or stopped responding to other treatments. Only 6 participants were enrolled before the study was stopped early. The go…
Phase: PHASE1 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
-
Experimental virus gets a second shot at brain tumors
Disease control TerminatedThis study tested the safety of giving a second dose of an experimental virus (C134) directly into the brain tumor of patients whose malignant glioma had returned. Only one patient was enrolled before the study was stopped. The goal was to see if repeat dosing was safe and tolera…
Phase: PHASE1 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
-
ERs could be key to boosting HPV shots in High-Risk adults
Prevention TerminatedThis study explored whether giving the HPV vaccine in the emergency department (ER) could help protect adults aged 18-45 who haven't been fully vaccinated. Researchers enrolled 34 participants and offered the vaccine during their ER visit, with follow-up doses at 2 and 6 months. …
Sponsor: University of Alabama at Birmingham • Aim: Prevention
Last updated Jun 27, 2026 12:09 UTC
-
New program aims to boost Well-Being in young black breast cancer survivors
Symptom relief TerminatedThis study tested a program called Y-AMBIENT designed to improve quality of life for young African American women who finished treatment for early or late-stage breast cancer. The program included educational sessions and check-ins, compared to a control group that received a coo…
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
-
New program aims to ease daily life for young black women battling breast cancer
Symptom relief TerminatedThis pilot study tested a four-month telephone program called Y-AMBIENT for young African American women (ages 18-44) with stage I-III breast cancer who were undergoing chemotherapy or radiation. The program included education sessions, follow-up calls, and videos to help manage …
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
-
HIV-Positive Men's mental health study shuts down after just one participant
Symptom relief TerminatedThis study aimed to see if acceptance and commitment therapy (ACT), a type of talk therapy, could help HIV-positive men with mental health issues like stress and anxiety. Only one person enrolled before the study was stopped early. Because of this, no meaningful results were obta…
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
-
Estrogen cream studied for Post-Birth injury recovery
Symptom relief TerminatedThis study tested whether a topical estrogen cream could improve sexual function and reduce incontinence in women who had a severe tear during childbirth. Thirty-eight women used either the cream or a placebo for six months. The trial was terminated early, so the findings are lim…
Phase: PHASE4 • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
-
Pain relief combo falls short: early trial halted
Symptom relief TerminatedThis study tested whether adding baclofen (a muscle relaxant) to buprenorphine (a painkiller) could improve pain relief in 19 healthy volunteers. Participants received either a placebo or baclofen alongside buprenorphine and then underwent heat-based pain tests. The trial was ter…
Phase: PHASE2, PHASE3 • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
-
Tiny study on Kids' arm casts halted before any answers
Knowledge-focused TerminatedThis study aimed to see if a cast that keeps the elbow straight or bent works better for certain forearm fractures in children. Only 3 children joined before the study was stopped early. Because of this, we cannot say which cast is better.
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC