University Of Alabama At Birmingham

This early-stage study tested the safety of the oral drug tazemetostat in 6 adults with peripheral T-cell lymphoma that had returned or stopped responding to prior treatments. The goal was to find a safe dose by watching for side effects in the first month. The study was terminat…

This study tested whether giving a second dose of an experimental virus (C134) directly into the brain tumor is safe for patients with recurrent malignant glioma, a type of aggressive brain cancer. Only one patient was enrolled before the study was stopped. The main goal was to m…

This study tested whether emergency departments can help adults aged 18-45 who haven't completed the HPV vaccine series get vaccinated. Researchers enrolled 34 participants and offered the vaccine during their ED visit, with follow-up doses at 2 and 6 months. The goal was to see …

This study tested a four-month telephone program called Y-AMBIENT designed to help young African American women (ages 18-44) with stage I-III breast cancer manage daily life during chemotherapy or radiation. The program included educational sessions, follow-up calls, and videos. …

This study aimed to find out whether a cast that keeps the elbow straight or bent works better for children with a specific type of forearm fracture. The researchers planned to enroll children aged 3 to 18 with a broken radius and ulna in the upper half of the arm. However, the s…

This study tested a program to improve quality of life for young African American women who finished treatment for early- or late-stage breast cancer. About 27 women took part in either the program or a comparison group. The goal was to see if the program helped with physical, me…

This study looked at whether a type of talking therapy called acceptance and commitment therapy (ACT) could help HIV-positive men deal with stress, anxiety, and other mental health concerns. The plan was to enroll many men, but the study was stopped early and only one person took…

This study looked at whether adding baclofen (a muscle relaxant) to buprenorphine (a painkiller) could improve pain relief in healthy adults. Researchers measured how participants reacted to heat pain after taking the drugs. The study was stopped early and involved 19 people.

This study tested whether a vaginal estrogen cream could improve recovery for women who had severe tears during childbirth. The trial aimed to see if the cream could improve sexual function and reduce problems like leaking urine or stool. The study was stopped early, and only 38 …

This study tested whether a dye called indocyanine green (ICG) can help surgeons see and protect the parathyroid glands during thyroid or parathyroid surgery. The dye makes the glands glow under a special camera, which may help avoid accidental damage. The study planned to enroll…