University Of Alabama At Birmingham

This study aimed to find the best way to cast a child's broken forearm. It compared two positions—one with the elbow bent and one with it straight—to see which kept the broken bones aligned better while they healed. The trial was for children aged 3-18 and was stopped early after…

This early-stage trial tested the safety of giving a second dose of an experimental treatment called C134 to adults with recurrent malignant brain tumors. C134 is a genetically modified cold sore virus designed to infect and kill tumor cells when injected directly into the brain.…

This study explored whether emergency departments could be used to help more adults get vaccinated against HPV, a virus that can cause several cancers. Researchers tested a program to offer the vaccine to eligible patients aged 18-45 who were visiting the ER and were not fully va…

This study tested whether applying a vaginal estrogen cream could help women recover from severe tears that sometimes happen during childbirth. Researchers wanted to see if the cream could improve sexual function and reduce problems with bladder and bowel control. The trial was s…

This study aimed to see if adding baclofen to the opioid medication buprenorphine could create stronger pain relief. Researchers tested this combination in 19 healthy volunteers by measuring their response to controlled heat pain. The goal was to develop safer, more effective pai…