Estrogen cream studied for Post-Birth injury recovery
NCT ID NCT05317364
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a topical estrogen cream could improve sexual function and reduce incontinence in women who had a severe tear during childbirth. Thirty-eight women used either the cream or a placebo for six months. The trial was terminated early, so the findings are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
estradiol vaginal cream
What this could lead to
If effective, this could offer a simple treatment to improve sexual function and reduce incontinence after childbirth injuries.
What could go wrong
The trial was terminated early with only 38 participants, so results are limited. Estrogen cream may not help and carries risks like blood clots or cancer in some women.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Alabama at Birmingham
Birmingham, Alabama, 35249, United States