Estrogen cream studied for Post-Birth injury recovery
NCT ID NCT05317364
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a topical estrogen cream could improve sexual function and reduce incontinence in women who had a severe tear during childbirth. Thirty-eight women used either the cream or a placebo for six months. The trial was terminated early, so the findings are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- estradiol vaginal cream
- What this could lead to
- If effective, this could offer a simple treatment to improve sexual function and reduce incontinence after childbirth injuries.
- What could go wrong
- The trial was terminated early with only 38 participants, so results are limited. Estrogen cream may not help and carries risks like blood clots or cancer in some women.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Alabama at Birmingham
Birmingham, Alabama, 35249, United States
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