URINARY INCONTINENCE

This trial tests a device called Adjustable Continence Therapy (ACT) for women with stress urinary incontinence caused by a weak urethral sphincter. The implant has two balloons placed near the bladder neck that can be adjusted after surgery to improve control. The study will enr…

This study compares two procedures for stress urinary incontinence (leaking urine with cough, sneeze, or exercise) in 358 women. One group gets a bulking agent injection to thicken the urethra lining; the other gets a small mesh sling to support the urethra. The goal is to see wh…

This study looks at how two different types of bladder medication affect thinking skills in women aged 60 and older who have sudden, strong urges to urinate. Participants will be randomly assigned to take one of two drugs or a placebo for 6 months. The goal is to see which option…

This study compares two surgical procedures for stress urinary incontinence in women aged 60 and older: a synthetic mesh sling (TVT) and a sling made from the patient's own tissue (autologous fascia). Researchers will track new pelvic pain at 6 months and cure rates at 5 years, a…

This study tests a new type of nerve stimulation to help Veterans with bladder control problems caused by nerve damage. A small wireless sensor is placed in the bladder to detect when it is filling and trigger stimulation to prevent leakage. The goal is to see if this approach wo…

This study tests whether a pelvic floor muscle training program, delivered through a mobile app, can reduce urinary incontinence and other pelvic floor disorders after childbirth. About 734 first-time pregnant women will either follow the app-based training or receive standard ca…

This study is testing the NXT Urodynamics System, a device used to measure how well the bladder stores and releases urine. Researchers want to confirm it is safe and works correctly in people with bladder problems like incontinence or overactive bladder. About 180 adults who need…

This study tests whether adding a beta-glucan moisturizing cream to standard skin care helps heal incontinence-associated dermatitis faster and reduces symptoms like pain, itching, and burning. Sixty adults with this skin condition will receive either the cream plus standard care…

This study tests a medical device (a perineal probe connected to a mobile app) for women with stress urinary incontinence. Participants use the device at home for 15 minutes, three times a week, plus two sessions with a physiotherapist. The goal is to see if this approach works a…

This study looks at urinary problems in people recovering from a stroke. Researchers compare patients with and without bladder issues and test two simple behavioral approaches: for those with thinking difficulties, training to go to the toilet immediately when they feel the urge;…

This study tests whether injecting Botox into the bladder wall during a standard prostate surgery (HoLEP) can better control overactive bladder symptoms like sudden urges to urinate and leakage. About 66 men aged 18-89 with these symptoms will be randomly assigned to get Botox or…

This study is testing a mobile app called MyHealtheBladder to help women veterans manage urinary incontinence. Researchers will compare two ways of introducing the app at 20 VA clinics to see which works better. The main goal is to see how many women use the app and how engaged t…

This study tests whether a small electrical device (TENS) can reduce pain for women undergoing an in-office procedure for stress urinary incontinence. About 100 women will be randomly assigned to receive either real TENS or a placebo device during the procedure. The goal is to se…

This study looks at whether combining Paula exercises (a type of pelvic floor training) with tibial nerve stimulation (a non-invasive nerve treatment) can help women with stress urinary incontinence. The goal is to reduce leakage, strengthen pelvic muscles, improve sexual functio…

This early study tests whether injecting a patient's own muscle fibers into the bladder neck or urethra is safe for treating urinary incontinence. Ten adult women with incontinence due to a weak outlet will be monitored for side effects and changes in leakage over 12 months.

This study tests whether combining Swiss ball exercises with diaphragmatic breathing can reduce stress urinary incontinence (leaking urine when coughing, sneezing, or exercising) in pregnant women. Forty-two pregnant women with mild to moderate incontinence will be split into two…

This early study tests a new urine collection device called PEASY in 20 hospitalized men with incontinence. Unlike current devices that use sticky adhesives, PEASY uses a gentle clamp on the foreskin to stay in place. The goal is to see if it causes less pain, itching, and discom…

This study tests whether cannabidiol (CBD), a compound from cannabis, can reduce urinary incontinence in people with recent spinal cord injury. Twenty adults with at least two leaks per day will take a purified CBD drug (Epidiolex) twice daily for 90 days. The main goal is to see…

This trial tests whether a structured nurse-led education session before prostate cancer surgery, plus a direct referral to pelvic floor physiotherapy, can reduce urinary incontinence afterward. Eighty men having their prostate removed will be randomly assigned to either standard…

This study is testing whether two devices used together can help new mothers with both depression and urinary incontinence. One device uses magnetic pulses to stimulate brain areas linked to mood, while the other strengthens pelvic floor muscles with electromagnetic energy. Sixty…

This early study tests a device called UCon, which is placed on the skin to send mild electrical pulses to nerves that control the bladder and bowel. The goal is to reduce symptoms like sudden urges, leaks, and frequent bathroom trips in women with overactive bladder or bowel dys…

This study is testing whether two devices used together can help perimenopausal and postmenopausal women with depression and sexual issues. One device delivers magnetic pulses to the brain (EXOMIND), and the other stimulates the pelvic floor muscles (EMSELLA). Sixty women aged 40…

This study tests whether a 4-week video education program can reduce urinary incontinence symptoms in women before they start pelvic floor rehabilitation. 144 women will either watch four short videos or receive a paper handout with similar information. Researchers will compare s…

This study tests whether adding posture and back-pelvis rehabilitation to standard pelvic floor muscle training can better reduce urinary incontinence in women. 78 women with stress, urge, or mixed incontinence will be randomly assigned to either pelvic floor training alone or co…

This study tests two non-surgical approaches to reduce urinary leakage in new mothers. About 216 women who recently gave birth and have bothersome leakage will either do guided pelvic floor exercises, use a home biofeedback device called leva®, or receive standard education. The …

This study tests whether sildenafil (the drug in Revatio, similar to Viagra) can reduce urine leakage in people with spinal cord injuries. Twenty-four adults who have at least three leaks per week will take either sildenafil or a placebo for four weeks. Researchers will track how…

This early study tests a device called UCon that sends mild electrical pulses through the skin to calm bladder nerves. Twenty men with overactive bladder will use the device at home for a few weeks. The goal is to see if it is safe and if it reduces urgency, leaks, and nighttime …

This study follows 380 women for a year after vaginal delivery to see how pelvic floor muscles and tissues recover. It also tests whether early, personalized pelvic floor exercises can improve symptoms like urine leakage and pelvic organ prolapse compared to standard care. Partic…

This study looks at brain activity in children with overactive bladder and daytime wetting compared to healthy children. Researchers use MRI scans to see if brain areas that control the bladder work differently. They also test if a gentle nerve stimulation treatment (TENS) change…

This study looks at the bacteria found in urine, the genital area, and stool of children with overactive bladder and daytime wetting, comparing them to healthy children. Researchers want to see if these bacteria differ between the groups and if they change with treatment or as ki…

This study aims to validate a Turkish version of the PRAFAB questionnaire, a short 5-question tool that measures both the physical and emotional impact of urinary incontinence in women. Researchers will enroll 63 women diagnosed with urinary incontinence to see if the questionnai…

This study is creating a detailed database of 150 adults with faecal incontinence, some of whom also have urinary incontinence (double incontinence). Researchers will use questionnaires and a special anal pressure test to compare factors like diarrhea, surgeries, and nerve condit…

This study tests a personalized mobile tool to help women with overactive bladder (OAB) start and stick with treatment. About 30 women will use the app to learn about their condition, track symptoms, and get support. The goal is to see if the tool improves bladder health knowledg…

This study looks at whether a short, intense trampoline workout can cause urine leakage or changes in pelvic floor structure in active women aged 18-40 who say they don't have incontinence. Thirty participants will jump for 10 minutes while researchers use ultrasound to measure p…