Botox shot into bladder during prostate surgery may ease urgent bathroom trips
NCT ID NCT05878951
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether injecting Botox into the bladder wall during a standard prostate surgery (HoLEP) can better control overactive bladder symptoms like sudden urges to urinate and leakage. About 66 men aged 18-89 with these symptoms will be randomly assigned to get Botox or a placebo during surgery. Researchers will track symptom improvement and side effects for several months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Botox (onabotulinumtoxinA)
- What this could lead to
- If it works, this could offer a way to reduce urgent, frequent urination and leakage in men already undergoing prostate surgery, improving their quality of life.
- What could go wrong
- This is a small, early-to-mid-stage trial, so results may not apply to all men. Risks include temporary urinary retention, bleeding, or infection after the procedure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Northwestern Medicine
RECRUITINGChicago, Illinois, 60611, United States
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