OVERACTIVE BLADDER

This study looks at how two different types of bladder medication affect thinking, memory, and daily life in women aged 60 and older who have sudden, strong urges to urinate. Participants will be randomly assigned to take one of two bladder drugs or a placebo for 6 to 9 months. T…

This study is testing a small device called eCoin that is implanted under the skin to stimulate a nerve in the leg. The goal is to help people who have sudden, strong urges to urinate and leak urine. About 200 adults with this condition will be followed for up to 2 years to see i…

This study tests a new ultrasound technique called Quantitative Ultrasound Bladder Vibrometry to measure bladder function without using a catheter. Researchers at Mayo Clinic will enroll adults with bladder problems or enlarged prostate to see if this method is accurate. The goal…

This study is tracking 500 adults with overactive bladder who use a new device called Tensi+. The device sends mild electrical pulses to a nerve in the ankle to help control bladder symptoms. Researchers want to see how well it works and if it is safe over one year.

This study tests whether a gentle, non-invasive brain stimulation technique called rTMS can improve overactive bladder symptoms (like frequent or urgent urination) in women with multiple sclerosis. Participants will receive either real or sham stimulation over 10 sessions, and re…

This study tests whether yoga can improve overactive bladder symptoms in children aged 8 to 18. Participants attend weekly yoga sessions for six weeks and complete surveys and urine tests to track changes. The goal is to see if yoga can be a helpful, drug-free option for managing…

This study tests whether the Emsella chair, which uses electromagnetic energy, can help people with overactive bladder. Participants will receive either real or sham treatments twice a week for four weeks. The goal is to see if the chair reduces urgency, frequency, and leakage. A…

This study tests whether women living in rural areas can use a small, at-home nerve stimulation device to manage overactive bladder symptoms. About 38 women will try the treatment and report how it affects their quality of life and bladder control. The goal is to see if this appr…

This study tests a device that uses mild electrical pulses to calm bladder nerves in men with overactive bladder. About 150 men will use the device for up to a year. The goal is to reduce sudden urges to urinate and improve quality of life.

This study looks at whether using lower radiation settings during a procedure to implant a nerve stimulator for overactive bladder is safe and effective. About 44 adults with overactive bladder will be randomly assigned to receive either standard or reduced radiation during the l…

This study tests whether a daily 500 mg cranberry extract (NDS-446) can change the bacteria in the bladder to reduce urgency and frequent urination in women with dry overactive bladder. Researchers will compare bacteria samples and symptom scores before and after 12 weeks of trea…

This study tests whether a device that uses radiofrequency energy inside the vagina can reduce sudden, urgent urine leaks in women with overactive bladder. About 200 women aged 22 to 80 will receive either the real device or a sham (fake) treatment in one session. Researchers wil…

This study looks at whether women with overactive bladder can safely and comfortably remove a temporary nerve testing lead at home instead of coming back to the doctor's office. About 30 women will be randomly assigned to remove the lead themselves at home or have it removed in t…

This study looks at women with urgent bladder control problems who choose a nerve stimulation device. It compares a 3-day test period to the usual 7-day test to see if the shorter time works just as well. The goal is to make the process faster and more convenient without reducing…

This study looks at whether injecting Botox into the bladder during standard prostate surgery (HoLEP) can better relieve overactive bladder symptoms like sudden urges and leaks. About 66 men aged 18-89 with these symptoms will take part. The goal is to see if the combination is s…

This study is testing a wearable sock-like device called the ZIDA Control Sock. It delivers a mild electrical pulse near the ankle to help control bladder function. The goal is to see if using this device at home once a week, in addition to their regular medication, can further r…

This study aims to collect electrical signals from the body in people with overactive bladder, fecal incontinence, or urinary retention. Researchers will gather these signals at several points during the therapy evaluation period. The goal is to better understand these conditions…

This study aims to understand how electrical stimulation of a nerve in the lower back helps people with overactive bladder. Researchers will measure nerve signals during treatment to see if they can predict which stimulation settings work best. The study involves 15 adults who ar…

This study looks at how often sexual problems occur in women with multiple sclerosis (MS) and how they connect to fatigue, depression, anxiety, bladder issues, and thinking problems. About 140 women with relapsing-remitting MS will fill out questionnaires and take simple tests. T…

This study looks at how bladder filling sensations change in people with multiple sclerosis who have overactive bladder. Researchers will measure these sensations during a standard test called urodynamics. The goal is to better understand the link between bladder feelings and sym…