Could a Take-Home antibiotic prescription cut unnecessary ER visits after bladder botox?

NCT ID NCT07648290

Recruiting now Symptom relief Sponsor: The Cleveland Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 2 times

Summary

This study tests whether giving patients a standing prescription for antibiotics to use at the first sign of a UTI after Botox for overactive bladder reduces unplanned healthcare visits. 260 women scheduled for Botox will either get the self-start prescription or follow standard triage care. The goal is to see if the self-start approach lowers calls, messages, and emergency visits for urinary symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nitrofurantoin (Macrobid) or alternative antibiotics
What this could lead to: If it works, this could simplify UTI management after Botox for overactive bladder, reducing unnecessary clinic visits.
What could go wrong: This is an early-phase study with no results yet. The self-start approach may not reduce healthcare use and could lead to antibiotic overuse or resistance.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

overactive bladder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVERACTIVE BLADDER

Contacts and locations

Locations

Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States

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