Botox vs. blood plasma: which works better for a bladder that Won't quit?

NCT ID NCT07693192

Ongoing Disease control Sponsor: Mahmoud Mohamed Farag Ali Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study compares two treatments for adults with overactive bladder that hasn't improved with standard medications. One group receives a single injection of Botox into the bladder, while the other gets three weekly instillations of Platelet-Rich Plasma (PRP) made from their own blood. Researchers track symptom changes, quality of life, and side effects over two years to see if PRP can match Botox's effectiveness with fewer risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Botulinum Toxin A (Botox) and Platelet-Rich Plasma (PRP)
What this could lead to: If PRP works as well as Botox but with fewer side effects, it could offer a safer, longer-lasting option for people with stubborn overactive bladder.
What could go wrong: This is a small, early-stage comparison. PRP is less studied for this condition, and results may not apply to everyone. Both treatments carry risks like infection or incomplete symptom relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

overactive bladder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVERACTIVE BLADDER

Contacts and locations

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Locations

Benha University Hospital

Banhā, Al Qalyubia, 13511, Egypt

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