Could a blood flow drug strengthen pelvic muscles to curb incontinence?
NCT ID NCT02983461
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial tests whether sildenafil, a drug that improves blood flow and muscle strength, can help postmenopausal women with stress or mixed urinary incontinence. The idea is that sildenafil may reduce pelvic floor muscle atrophy, improving symptoms. Participants take sildenafil or a placebo three times daily for 10 weeks, and urine leakage is measured with a pad test.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sildenafil
- What this could lead to
- If sildenafil strengthens pelvic floor muscles, it could offer a new, non-surgical treatment for urinary incontinence in postmenopausal women.
- What could go wrong
- This is a small, early-phase trial. The drug may not improve incontinence, and side effects are possible. Results may not apply to all women.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Texas Medical Branch
Galveston, Texas, 77555, United States
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