Injection vs sling: which works better for leaky bladder?
NCT ID NCT06480227
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two procedures for stress urinary incontinence (leaking urine with cough, sneeze, or exercise) in 358 women. One group gets a bulking agent injection to thicken the urethra lining; the other gets a small mesh sling to support the urethra. The goal is to see which provides more relief at 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Bulkamid Transurethral Bulking Agent (injection) and Solyx Single-Incision Sling (mesh device)
- What this could lead to
- If this trial succeeds, it could show which of two minimally invasive procedures works better for stress urinary incontinence, helping women choose the most effective treatment.
- What could go wrong
- This is a comparative effectiveness trial, not a cure. Both procedures have risks like infection, pain, or failure, and results may not apply to all women.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MIXED URINARY INCONTINENCE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Brown/ Women and Infants Hospital of Rhode Island, Division of Urogynecology and Reconstructive Pelvic Surgery
RECRUITINGProvidence, Rhode Island, 02903, United States
-
Duke University, Duke Division of Urogynecology and Reconstructive Pelvic Surgery
RECRUITINGDurham, North Carolina, 27707, United States
-
Kaiser Permanente -- San Diego
RECRUITINGSan Diego, California, 92110, United States
-
University of California at San Diego
RECRUITINGLa Jolla, California, 92037-0974, United States
-
University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
-
University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
-
University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a blood flow drug strengthen pelvic muscles to curb incontinence?
- What does life feel like for children with a rare birth defect? a new study asks
- One surgery, two problems? a new approach to pelvic floor repair
- Can ancient qigong movements fortify pelvic health after childbirth?
- Could a simple video calm nerves before a bladder test?
- Can a virtual garden help women regain bladder control?