STRESS URINARY INCONTINENCE

This study compares two procedures for stress urinary incontinence (leaking urine with cough, sneeze, or exercise) in 358 women. One group gets a bulking agent injection to thicken the urethra lining; the other gets a small mesh sling to support the urethra. The goal is to see wh…

This study follows about 195 women for up to 10 years after they receive a mesh sling (GYNECARE TVT ABBREVO) to treat stress urinary incontinence (leaking urine when coughing, sneezing, or exercising). The main goal is to see how many women are still dry after 5-10 years. Partici…

This study compares two medical sling devices used to treat stress urinary incontinence in women. About 300 women will receive either a single-incision sling or a standard transobturator sling. Researchers will check how well each device stops urine leakage during a cough test an…

This study looks at how well a surgical sling (a small mesh tape) works for women with stress urinary incontinence—leaking urine when coughing, sneezing, or exercising. Researchers will measure bladder function before and after surgery in 200 women. The goal is to see if the slin…

This study tests a medical device (a perineal probe connected to a mobile app) for women with stress urinary incontinence. Participants use the device at home for 15 minutes, three times a week, plus two sessions with a physiotherapist. The goal is to see if this approach works a…

This study tests whether a once-daily pill called orforglipron can reduce stress urinary incontinence (leaking urine during movement) in women with obesity or overweight. About 1000 adult women will receive either the drug or a placebo for about 58 weeks. The main goal is to see …

This study compares two types of core exercises—hypopressive training and transversus abdominis focused training—to see which better reduces urinary incontinence and improves pelvic floor function and quality of life in women after childbirth. Sixty women who had a normal vaginal…

This study compares two types of exercises—hypopressive exercises and the Paula method—to see which better helps postpartum women with urinary incontinence. Sixty women who had a vaginal delivery and leak urine at least once a week will do one of the two exercises twice a week fo…

This study compares two procedures—a sling or a bulkamide injection—to treat stress urinary incontinence in women who are also having vaginal prolapse repair. About 476 participants will be randomly assigned to one of the two treatments and followed for 24 months. The goal is to …

This study compares a mobile app-guided pelvic floor exercise program to standard in-person rehabilitation for women with stress or mixed urinary incontinence. Thirty-two adult women will follow either the app or in-person sessions for 3 months. Researchers will measure changes i…

This study tests a 12-week pelvic floor exercise program for women aged 65 and older living in nursing homes who have stress urinary incontinence (leakage with coughing, sneezing, or movement). One group will do standard exercises while watching and imagining themed videos to imp…

This study tests a device that sends mild electrical pulses to the pelvic floor muscles to help men who have bladder leakage after prostate cancer treatment. About 41 men with moderate leakage for at least 6 months will use the device at home for 20 minutes a day, 5 days a week, …

This study compares two home exercise programs for women with stress urinary incontinence (leakage during coughing, sneezing, or exercise). One program focuses on pelvic floor muscles, the other on core stabilization. Fifty-one women will participate in a 12-week program, and res…

This study tests a new device designed to help women with stress urinary incontinence—leaking urine when coughing, sneezing, or exercising. The trial will compare the real device to a sham (fake) device in 96 women over 12 weeks. The main goal is to see if the device reduces urin…

This study compares a newer exercise method called Dynamic Neuromuscular Stabilization (DNS) to standard pelvic floor muscle training for women with stress urinary incontinence (leaking urine when coughing, sneezing, or exercising). About 62 women will be randomly assigned to one…

This study tests a chair called Emsella that uses electromagnetic energy to treat stress urinary incontinence—leaking urine when coughing, sneezing, or exercising. About 110 adults aged 18 to 80 will sit in either the real chair or a fake (sham) chair to see if it reduces leaks b…

This study tests whether a Chinese herbal medicine formula called S-2196 can safely reduce urine leakage in women aged 55 and older with stress urinary incontinence. Fifteen participants will take the herbal formula for 2 weeks, and researchers will measure changes in leakage amo…

This study looks at whether taking antibiotics before a procedure to treat stress urinary incontinence (leaking urine with cough or sneeze) can lower the chance of getting a urinary tract infection (UTI) afterward. About 138 women will receive either antibiotics or a placebo befo…

This study tests whether injecting sterile saline into the space behind the pubic bone before placing a sling for stress incontinence can reduce the risk of accidentally poking the bladder. About 300 women scheduled for this surgery will be randomly assigned to receive the inject…

This study is a long-term registry that will follow 1,000 women who receive pelvic mesh products for stress urinary incontinence or pelvic organ prolapse. Researchers will track how well the mesh works and any complications over 5 to 10 years. The goal is to gather real-world dat…

This early study tests a new approach for stress urinary incontinence (leaking urine when coughing, sneezing, or exercising). Researchers will stimulate nerves near the urethra in 20 women to see if it increases urethral pressure, which could help prevent leaks. The goal is to un…

This study looks at whether using ultrasound imaging and muscle activity sensors together can help women with weak pelvic floor muscles stick with their exercises and get better results. About 70 women will try different feedback methods during training. The goal is to find the b…