STRESS URINARY INCONTINENCE

This study tests whether injecting a woman's own muscle cells into the urinary sphincter can reduce leaks in those with stress urinary incontinence that persists or returns after surgery. Half of the 96 participants receive the cell injection, half receive a placebo. The goal is …

This study tested an experimental drug called VMB-100, which uses mRNA to help repair the muscle that controls urine flow. It was designed for women aged 18 to 55 with moderate stress urinary incontinence that did not improve with standard treatments. The drug was injected direct…

This study follows about 200 women who had surgery for stress urinary incontinence using the GYNECARE TVT EXACT sling. Researchers want to see if the sling still works 5 to 10 years later by checking if a cough still causes leaking. They also ask women about their symptoms, quali…

This study tests whether a 2-minute perineal massage before a pessary check can reduce pain and improve comfort. About 68 women with prolapse or stress incontinence will try both massage and a gel-only method at separate visits. The goal is to find a simple, drug-free way to make…

This study tests whether a non-invasive magnetic stimulation device can strengthen pelvic floor muscles and reduce or stop stress urinary incontinence (leaking urine when coughing, sneezing, or exercising) in adult women. About 158 women will receive the treatment and report thei…

This study compares two surgical sling methods (single-incision vs. retropubic) for treating stress urinary incontinence in women undergoing minimally invasive pelvic organ prolapse repair. About 180 women will be randomly assigned to one of the two sling types. The goal is to se…

This study looks at whether starting pelvic floor physical therapy before prostate surgery (HoLEP) can help men recover from stress urinary incontinence faster. About 72 men who are already scheduled for HoLEP will be randomly assigned to start therapy either before surgery or on…

This study tests whether injecting Botox into the bladder muscle can reduce urine leakage in women with stress urinary incontinence. About 20 women who have not improved with other treatments will receive the injection and be monitored for changes in leakage and side effects. The…

This study tests whether a laser applied to the vagina can help women with stress urinary incontinence (leaking urine when coughing, sneezing, or exercising). 144 women will receive the laser treatment and be followed for 6 months. The main goal is to see if the treatment reduces…

This study tests a device called PelviSense that helps women with stress urinary incontinence (leaking urine when coughing, sneezing, or exercising) by giving real-time feedback on pelvic muscle exercises. About 132 women aged 18-60 will either use the device with standard exerci…

This study looks at how blood flow to the urethra relates to bladder pressure in people with and without stress urinary incontinence. Researchers will use advanced ultrasound imaging to measure blood supply and compare it to standard pressure tests. The goal is to better understa…