Botox shot may help stop leaky bladder – early study hopes

NCT ID NCT04984317

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests whether a one-time injection of Botox into the bladder muscle can reduce urine leakage in women with stress urinary incontinence. Twenty women who have not improved with other treatments will receive the injection and be monitored for changes in leakage and side effects. The trial is currently suspended, and results are not yet available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

onabotulinumtoxin A (Botox)

What this could lead to

If it works, this could offer a new, non-surgical option to reduce urine leakage in women with stress incontinence.

What could go wrong

This is a very early, small trial that is currently suspended. It may not show clear benefit, and risks include infection, urinary retention, and pelvic pain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

female stress incontinence Urinary Incontinence Urinary Incontinence, Stress

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Weill Cornell Medicine

    New York, New York, 10065, United States