Botox shot may help stop leaky bladder – early study hopes

NCT ID NCT04984317

Terminated Disease control Sponsor: Northwell Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests whether a one-time injection of Botox into the bladder muscle can reduce urine leakage in women with stress urinary incontinence. Twenty women who have not improved with other treatments will receive the injection and be monitored for changes in leakage and side effects. The trial is currently suspended, and results are not yet available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: onabotulinumtoxin A (Botox)
What this could lead to: If it works, this could offer a new, non-surgical option to reduce urine leakage in women with stress incontinence.
What could go wrong: This is a very early, small trial that is currently suspended. It may not show clear benefit, and risks include infection, urinary retention, and pelvic pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

female stress incontinence Urinary Incontinence Urinary Incontinence, Stress

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STRESS URINARY INCONTINENCE

Contacts and locations

Locations

Weill Cornell Medicine

New York, New York, 10065, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.