Testosterone shots aim to strengthen pelvic floor in older women

NCT ID NCT06111209

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether weekly testosterone injections can increase pelvic floor muscle size and improve stress urinary incontinence in women aged 60 and older. The trial involves 30 participants and uses MRI to measure muscle changes. It is a small, early-stage proof-of-concept study.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
testosterone cypionate
What this could lead to
If it works, this could point toward a new treatment for stress urinary incontinence in older women by strengthening pelvic floor muscles.
What could go wrong
This is a very small pilot study with only 30 participants, so results may not apply to everyone. It is also early-stage, and the primary outcome is muscle volume, not direct symptom improvement.

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Conditions

The condition(s) this trial relates to.

female stress incontinence Pelvic Floor Disorders Urinary Incontinence, Stress

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

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