URINARY INCONTINENCE

This study compares two treatments for stress urinary incontinence (leaking urine with cough, sneeze, or exercise) in 358 women who haven't gotten enough relief from conservative care. One group gets a bulking agent injection into the urethra (up to two injections over 12 months)…

This early-phase study tests whether injecting a patient's own muscle fibers into the bladder neck can safely treat urinary incontinence. Ten adult women with stress incontinence due to a weak sphincter will be monitored for side effects like bleeding or infection. Researchers wi…

This study looks at how two different types of bladder medication affect thinking, memory, and daily life in women aged 60 and older who have sudden, strong urges to urinate. Participants will be randomly assigned to take one of two bladder drugs or a placebo for 6 to 9 months. T…

This study tests a new type of nerve stimulation that uses a wireless sensor inside the bladder to detect when it's filling and trigger stimulation to prevent leakage. It is for Veterans with bladder control problems caused by nerve damage. The goal is to see if this approach wor…

This study compares two types of surgical slings—one made from synthetic mesh and one from the patient's own tissue—to treat stress urinary incontinence in women aged 60 and older. Researchers will track pain and cure rates for up to five years after surgery. The goal is to find …

This study tests whether doing pelvic floor muscle exercises during a first pregnancy can reduce the chance of urinary incontinence, anal incontinence, and pelvic organ prolapse after childbirth. About 734 first-time mothers will be assigned to either a training program or standa…

This study is checking if a device called the NXT system works well and is safe for measuring bladder function. It will include 180 adults who need a urodynamic study for problems like urinary incontinence or overactive bladder. The main goal is to see if the device measures all …

This study tests whether adding posture and back exercises to standard pelvic floor training can improve urinary incontinence in women more than pelvic floor exercises alone. 78 women aged 18-65 with stress, urge, or mixed incontinence will be randomly assigned to 12 weeks of eit…

This study looks at whether combining Paula exercises (a type of pelvic floor training) with tibial nerve stimulation can help women with stress urinary incontinence. About 52 women who have had at least two full-term vaginal deliveries and leak urine during activities like cough…

This study tests whether a small electrical device (TENS) can reduce pain during an outpatient procedure for stress urinary incontinence. About 100 women will be randomly assigned to receive either real TENS or a placebo device during the procedure. Researchers will measure pain …

This study tests whether a purified form of CBD (Epidiolex) can reduce urinary incontinence in people who recently had a spinal cord injury. Twenty adults with at least two leaks per day will take CBD for 90 days and track their symptoms using a smartphone app. The goal is to see…

This study tests two nonsurgical treatments—pelvic floor muscle training and a home biofeedback device—against standard education to reduce urinary leakage in new mothers. About 216 first-time moms who had a vaginal delivery and are at high risk for pelvic floor problems will tak…

This study tests a new device called PEASY that collects urine from men who have trouble controlling their bladder. It is designed to be more comfortable than current options by using a non-adhesive strap that holds it in place without glue. The study will enroll 20 uncircumcised…

This study tests whether two devices (EXOMIND and EMSELLA) used together can improve depressive symptoms and sexual function in women aged 40 and older who are in perimenopause or menopause. Participants will receive twelve treatments and complete questionnaires about their mood,…

This study is testing whether two devices, EXOMIND and EMSELLA, used together can help improve depressive symptoms and urinary incontinence in women who gave birth within the last 5 years. About 60 women will receive 12 treatment sessions and complete questionnaires about their m…

This study looks at whether doing Swiss ball exercises along with deep breathing can help pregnant women who leak urine when they cough, sneeze, or exercise. About 42 pregnant women with mild to moderate stress urinary incontinence will be split into two groups: one doing ball ex…

This study tests whether a structured nurse-led education session and direct referral to pelvic floor physiotherapy before prostate removal surgery can reduce urine leakage afterward. About 80 men scheduled for prostate cancer surgery will be randomly assigned to either standard …

This study tests a wearable device called UCon that sends mild electrical pulses through the skin to calm overactive bladder muscles. It aims to reduce sudden urges, frequent trips to the bathroom, and nighttime urination in men. Twenty male participants will use the device at ho…

This study tests a smartphone-based tool to help women with overactive bladder learn about their condition and stay on treatment. Many people stop therapy early due to cost, side effects, or lack of information. The app provides personalized tips and education to improve symptoms…

This early study tests a device called UCon that uses mild electrical pulses through the skin to calm overactive bladder and bowel muscles. About 20 women with symptoms like sudden urges, frequent bathroom trips, or leakage will try it. The goal is to see if it's safe and can cut…

This study tests whether sildenafil (the drug in Viagra) can reduce urine leakage in people with spinal cord injuries. About 24 adults will take either sildenafil or a placebo for 4 weeks and track their daily bladder leaks. The goal is to see if this medication can improve bladd…

This study looks at whether injecting Botox into the bladder during standard prostate surgery (HoLEP) can better relieve overactive bladder symptoms like sudden urges and leaks. About 66 men aged 18-89 with these symptoms will take part. The goal is to see if the combination is s…

This study tests whether a 4-week video education program can reduce urinary incontinence symptoms in women before they begin pelvic floor physical therapy. About 144 women will either watch the videos or receive a paper handout with similar information. Researchers will compare …

This study is testing whether a short, 5-question survey called PRAFAB is a reliable way to measure urinary incontinence in Turkish-speaking women. Researchers will enroll 63 women diagnosed with urinary incontinence to see if the questionnaire accurately captures both the physic…

This study follows 380 women for a year after vaginal childbirth to see how pelvic floor muscles and tissues recover. It also tests whether early, personalized pelvic floor muscle training can improve symptoms like urine leakage and pelvic organ prolapse compared to standard care…

This study looks at brain activity in children with overactive bladder and daytime wetting compared to healthy children. Researchers use brain scans to see if a nerve stimulation treatment changes how the brain controls the bladder. The goal is to understand why some children hav…

This study looks at whether a 10-minute trampoline session can cause urine leaks or change pelvic floor shape in active women aged 18-40 who say they don't have bladder control issues. Participants will jump on a mini-trampoline while researchers use ultrasound to check for any c…

This study looks at how well a mobile app called MyHealtheBladder works for women veterans who have urinary incontinence (bladder leaks). The goal is to see if the app helps more women get care and stay engaged. About 20 VA clinics will take part, and researchers will track how m…

This study looks at bacteria found in urine, the genital area, and stool of children with overactive bladder and daytime wetting, and compares them to healthy children. Researchers want to see if these bacterial communities are different and if they change with treatment or age. …

This study is creating a detailed database of 150 adults with faecal incontinence to compare those who also have urinary incontinence (double incontinence) with those who do not. Researchers will look at factors like past surgeries, nerve conditions, and diarrhea, and use special…