Glow-in-the-dark dye could help surgeons save tiny glands during thyroid surgery

NCT ID NCT06169735

Terminated Disease control Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a fluorescent dye called indocyanine green can help surgeons find and protect the parathyroid glands during thyroid or parathyroid surgery. The dye is injected into the bloodstream and makes the glands glow under a special camera. The trial enrolled 417 adults but was terminated early, so the full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Indocyanine green (a fluorescent dye injected into the bloodstream)
What this could lead to: If it works, this technique could help surgeons better identify and preserve parathyroid glands during thyroid surgery, reducing complications.
What could go wrong: The trial was terminated early, so results are limited. The dye may not work for everyone, and some people cannot receive it due to allergies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

adenoma parathyroid gland adenoma parathyroid gland disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOMA PARATHYROID DYSFUNCTION

Contacts and locations

Locations

UAB Callahan Eye

Birmingham, Alabama, 35233, United States

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