Hormones may shape how we feel pain, new study suggests

NCT ID NCT05787470

First seen Jun 26, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study looks at how hormones like testosterone and estradiol influence pain sensitivity in cisgender and transgender individuals. Researchers will test pain responses to heat, cold, and pressure, and analyze blood samples for hormone levels and immune markers. The goal is to understand biological factors behind pain differences, which could lead to better pain treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could reveal how hormones influence pain perception, potentially guiding personalized pain management approaches.
What could go wrong
This is an observational study with no treatment, so it won't directly change medical practice. Results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

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