Could a common antibiotic help kids breathe easier with severe RSV?
NCT ID NCT05026749
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the antibiotic azithromycin can help children with severe RSV infection who need breathing support in the ICU. About 370 children will receive either azithromycin or a placebo for three days. The main goal is to see if the drug shortens the time they need to stay in the hospital.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
azithromycin
What this could lead to
If it works, this could provide a simple, widely available treatment to shorten hospital stays for children with severe RSV.
What could go wrong
This is a single drug tested in one setting; results may not apply to all children, and azithromycin may not improve outcomes or could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
RECRUITINGChicago, Illinois, 60611, United States
Contact Email: •••••@•••••
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Children's National Hospital
RECRUITINGWashington D.C., District of Columbia, 20010, United States
Contact Email: •••••@•••••
Contact
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Nationwide Children's Hospital
RECRUITINGColumbus, Ohio, 43205, United States
Contact Email: •••••@•••••
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Oklahoma Health Sciences
RECRUITINGOklahoma City, Oklahoma, 73104, United States
Contact Email: •••••@•••••
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Rainbow Babies and Children's Hospital
RECRUITINGCleveland, Ohio, 44106, United States
Contact Email: •••••@•••••
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Riley Children's Health
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Email: •••••@•••••
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St. Louis Children's Hospital
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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The University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75247, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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University of Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68198, United States
Contact Email: •••••@•••••
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University of North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27599, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale School of Medicine
RECRUITINGNew Haven, Connecticut, 06520-8064, United States
Contact Email: •••••@•••••