MULTIPLE SCLEROSIS
Clinical trials for MULTIPLE SCLEROSIS explained in plain language.
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Plasma swap shows promise for tough MS Flare-Ups
Disease control CompletedThis study tested whether plasma exchange (a blood-filtering treatment) helps people with multiple sclerosis who have severe relapses that do not get better with steroids. 38 adults took part and were randomly assigned to receive either real plasma exchanges or a sham (fake) proc…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE3 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated May 16, 2026 22:33 UTC
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Head-to-Head: which MS drug works better in daily life?
Disease control CompletedThis study looked at over 2,600 people with multiple sclerosis to compare two drugs, Kesimpta and Ocrevus, using real-world insurance data. The goal was to see which one better prevents relapses and reduces healthcare visits and costs. Both drugs are already approved for MS, and …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 16, 2026 22:31 UTC
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Real-World study reveals how MS drug ocrelizumab performs outside the lab
Disease control CompletedThis study followed over 1700 people with multiple sclerosis (MS) who were prescribed ocrelizumab as part of their normal care. Researchers tracked changes in symptoms like fatigue, walking, hand function, and thinking, as well as side effects. The goal was to see how well the dr…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 16, 2026 22:27 UTC
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MS drug ocrelizumab shows promise in Long-Term study
Disease control CompletedThis study looked at how well and how safely the drug ocrelizumab works over a longer period for people with multiple sclerosis (MS). It included over 1,000 participants who had already taken ocrelizumab in earlier Roche-sponsored studies. Researchers tracked disability progressi…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 16, 2026 22:27 UTC
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Brain scans reveal Ocrelizumab's impact on MS inflammation
Disease control CompletedThis study looked at how the drug ocrelizumab changes brain inflammation in people with multiple sclerosis (MS). Twenty-two adults with MS had special brain scans before and after one year of treatment. The goal was to see if ocrelizumab reduces inflammation in different brain ar…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New MS drug shows promise in Head-to-Head trial against standard therapies
Disease control CompletedThis study tested a monthly injection of ofatumumab against other standard first-line medications for people newly diagnosed with relapsing multiple sclerosis (MS). The goal was to see which treatment better controls disease activity without relapses, new brain lesions, or worsen…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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New online program helps MS patients stay on their feet
Disease control CompletedThis study tested a new online program to help people with multiple sclerosis prevent falls. The program taught self-management strategies to reduce fall risks. 45 adults with MS took part. The goal was to see if the program was practical and helpful.
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Karolinska Institutet • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Swiss MS patients on kesimpta: Real-World results show strong disease control
Disease control CompletedThis study looked at 107 adults in Switzerland with relapsing multiple sclerosis who were taking the drug Kesimpta (ofatumumab) as part of their normal medical care. The goal was to see how well the drug prevented new disease activity, such as relapses, new brain lesions, or wors…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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Blood filtering therapy shows promise for MS in small trial
Disease control CompletedThis study tested a treatment called extracorporeal photopheresis (ECP) in 15 people with multiple sclerosis (MS). ECP involves taking blood, treating it with light and a drug, then returning it to the body. The goal was to see if it is safe and might help improve walking, hand f…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1, PHASE2 • Sponsor: Abu Dhabi Stem Cells Center • Aim: Disease control
Last updated May 08, 2026 12:04 UTC
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Could a diabetes drug and an antihistamine help repair MS damage?
Disease control CompletedThis study tested whether combining two common drugs—metformin (for diabetes) and clemastine (an antihistamine)—can help repair the protective coating around nerve cells in people with relapsing-remitting multiple sclerosis. 70 participants took the drug combination or a placebo …
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Cambridge University Hospitals NHS Foundation Trust • Aim: Disease control
Last updated May 07, 2026 18:41 UTC
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New hope for MS patients: cladribine tablets studied after other drugs fail
Disease control CompletedThis study looked at how well cladribine tablets work for people with relapsing forms of multiple sclerosis (MS) who had a poor response to other oral or infusion treatments. Researchers tracked the number of relapses and how satisfied patients were with the medication over two y…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: EMD Serono Research & Development Institute, Inc. • Aim: Disease control
Last updated May 06, 2026 16:13 UTC
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Can a Gold-Based drug revive brain cells in MS?
Disease control CompletedThis study tested a drug called CNM-Au8 in 33 people with relapsing multiple sclerosis (MS). The goal was to see if it could improve energy levels in brain cells, which may help slow the disease. Participants took the drug for 12 weeks while researchers used special brain scans t…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Clene Nanomedicine • Aim: Disease control
Last updated May 04, 2026 16:31 UTC
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Own stem cells tested against MS in new trial
Disease control CompletedThis study tested whether a person's own stem cells (called HB-adMSCs) could improve quality of life for people with multiple sclerosis. 24 adults with relapsing-remitting MS received either the stem cells or a placebo through 6 infusions over a year. The main goal was to see if …
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Hope Biosciences Research Foundation • Aim: Disease control
Last updated Apr 26, 2026 20:02 UTC
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New Gadolinium-Free MRI dye could make brain scans safer
Diagnosis CompletedThis study tested a new MRI contrast agent called RVP-001, which does not contain gadolinium, in 18 adults with brain lesions from conditions like tumors or multiple sclerosis. The goal was to see if it is safe and effective at highlighting these lesions compared to standard gado…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Reveal Pharmaceuticals Inc. • Aim: Diagnosis
Last updated May 16, 2026 22:29 UTC
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Eye-Tracking gadget aims to gauge MS severity without a doctor visit
Diagnosis CompletedThis study tested a device called ETNA-MS that uses eye-tracking to estimate disability levels in people with multiple sclerosis (MS). Researchers compared the device's results to standard in-person exams by neurologists. The goal was to see if the device could accurately measure…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Innodem Neurosciences • Aim: Diagnosis
Last updated May 05, 2026 11:53 UTC
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Shocking new hope for MS swallowing problems?
Symptom relief CompletedThis study looked at whether adding a mild electrical stimulation to standard swallowing exercises helps people with multiple sclerosis who have trouble swallowing. 136 participants were split into two groups: one received real stimulation plus therapy, the other received fake st…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: I.R.C.C.S. Fondazione Santa Lucia • Aim: Symptom relief
Last updated May 16, 2026 22:33 UTC
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Shocking bladder troubles away: nerve zaps ease MS symptoms
Symptom relief CompletedThis study tested two non-invasive nerve stimulation methods—one on the ankle and one on the lower back—to see if they could reduce overactive bladder symptoms in women with multiple sclerosis. 42 women took part, and the researchers measured changes in bladder function and quali…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization • Aim: Symptom relief
Last updated May 16, 2026 22:33 UTC
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Mind over MS: imagining movement boosts walking and eases fatigue
Symptom relief CompletedThis study looked at whether adding motor imagery (imagining movements) and action observation (watching movements) to standard physical therapy helps people with multiple sclerosis. 48 adults with mild to moderate MS took part. The goal was to see if these mental techniques impr…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Hacettepe University • Aim: Symptom relief
Last updated May 16, 2026 22:32 UTC
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Digital fall prevention program shows promise for MS patients
Symptom relief CompletedThis study tested a digital group program called 'Fewer Falls in MS' to help people with multiple sclerosis prevent falls. 240 participants who had fallen in the past year took part. The program included eight online sessions and home exercises, and the researchers compared fall …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Karolinska Institutet • Aim: Symptom relief
Last updated May 16, 2026 22:31 UTC
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Home-Based voice training shows promise for MS patients
Symptom relief CompletedThis study tested whether a voice treatment called LSVT-Loud, usually done in a clinic, can work when done at home via video calls for people with multiple sclerosis. Twenty participants with voice problems completed the program. The goal was to see if the therapy could help them…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Fondazione Don Carlo Gnocchi Onlus • Aim: Symptom relief
Last updated May 16, 2026 22:30 UTC
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New exercise combo eases bladder issues in MS patients
Symptom relief CompletedThis study tested whether adding Dynamic Neuromuscular Stabilization (DNS) exercises to standard pelvic floor training helps women with multiple sclerosis (MS) who have bladder control problems. Twenty-four women aged 28-54 completed an 8-week program. The goal was to see if the …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated May 16, 2026 22:30 UTC
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Mind and body combo boosts mobility in MS patients
Symptom relief CompletedThis study looked at whether adding cognitive behavior therapy (a type of talk therapy) to supervised Pilates exercises could help people with multiple sclerosis walk better and keep their balance. 90 adults with mild to moderate MS took part. The goal was to see if the combined …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated May 16, 2026 22:30 UTC
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Shock waves to the feet improve balance in MS patients, study finds
Symptom relief CompletedThis study tested if applying shock wave therapy to the feet could improve balance and walking in people with multiple sclerosis (MS). Fifty-four adults with MS received the treatment three times a week for six weeks. Researchers measured foot sensation, joint position sense, and…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Furkan Bilek • Aim: Symptom relief
Last updated May 16, 2026 22:29 UTC
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Water workouts may ease MS balance and fatigue woes
Symptom relief CompletedThis study looked at whether a water-based exercise program (hydrotherapy) could help improve balance and reduce fatigue in people with multiple sclerosis. 26 adults with relapsing-remitting MS took part. The results suggest that hydrotherapy may be a helpful way to manage these …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Thessaly • Aim: Symptom relief
Last updated May 16, 2026 22:29 UTC
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Robot suit helps MS patients walk faster in new trial
Symptom relief CompletedThis study tested whether a self-balancing robotic exoskeleton (Atalante) could improve walking speed in people with multiple sclerosis better than standard physical therapy. Sixty participants with moderate to severe walking difficulty were randomly assigned to 24 sessions of ei…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Multiple Sclerosis Center of Catalonia • Aim: Symptom relief
Last updated May 16, 2026 22:29 UTC
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Brain games and light exercise aim to sharpen MS minds
Symptom relief CompletedThis pilot study tested two different computer-based brain training programs that also include light physical activity. The goal was to see if they could help improve thinking skills like memory and attention in people with multiple sclerosis (MS). The study planned to enroll 40 …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 16, 2026 22:29 UTC
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Can yoga or physical therapy ease MS symptoms? small study finds out
Symptom relief CompletedThis study tested whether an 8-week yoga program or standard physical therapy helps people with multiple sclerosis feel less tired, walk better, and improve their quality of life. Twenty adults with MS were split into two groups and did supervised sessions three times a week. The…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Istanbul Rumeli University • Aim: Symptom relief
Last updated May 16, 2026 22:29 UTC
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Wheelchair workout study shows promise for MS patients
Symptom relief CompletedThis study tested a 16-week exercise program designed for wheelchair users with multiple sclerosis. Researchers wanted to see if the program was safe, doable, and liked by participants. They also checked for changes in health, MS symptoms, and exercise habits. The study involved …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated May 16, 2026 22:29 UTC
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Can talk therapy beat MS fatigue? new study says maybe
Symptom relief CompletedThis study tested three types of cognitive behavioral therapy (relaxation, activity planning, and changing thoughts) delivered by video call to help with fatigue in people with multiple sclerosis. 21 adults with MS and chronic fatigue took part. The goal was to see if the therapy…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated May 16, 2026 22:28 UTC
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Electric zaps to nerves may boost hand strength in MS patients
Symptom relief CompletedThis study tested two types of electrical nerve stimulation (PENS and TENS) to see if they could improve hand function in people with multiple sclerosis. 28 adults received one session of stimulation to nerves in the arm. Researchers measured hand dexterity, strength, and touch s…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Universidad de Burgos • Aim: Symptom relief
Last updated May 16, 2026 22:26 UTC
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Laughter yoga shows promise for MS fatigue and sleep
Symptom relief CompletedThis study tested whether laughter yoga can reduce fatigue, improve sleep quality, and boost psychological well-being in people with multiple sclerosis (MS). Forty adults with MS took part, and their symptoms were measured before and after six weeks of laughter yoga sessions. The…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Tokat Gaziosmanpasa University • Aim: Symptom relief
Last updated May 15, 2026 11:58 UTC
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Double-Duty training shows promise for MS symptoms
Symptom relief CompletedThis study looked at whether training that combines physical and mental tasks (like walking while counting) can improve balance, walking, thinking, and fatigue in people with multiple sclerosis. Twenty-six adults with MS took part. The goal was to see if this type of training hel…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Ege University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Could VR boxing help MS patients get stronger?
Symptom relief CompletedThis small study tested whether a short, high-intensity virtual reality boxing program is safe and doable for people with multiple sclerosis. Five participants used a VR headset for 10-minute sessions twice a week for 8 weeks. The goal was to see if it could improve movement, thi…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Vigo • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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New online therapy eases anxiety and depression in MS patients
Symptom relief CompletedThis study tested an 8-week online program designed to help people with multiple sclerosis (MS) improve their problem-solving and coping skills. The goal was to see if the program was easy to use and could reduce anxiety and depression. Thirty adults with MS in Lebanon took part,…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: American University of Beirut Medical Center • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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Acupressure offers hope for MS symptom relief
Symptom relief CompletedThis study looked at whether acupressure, a technique that applies pressure to specific points on the body, can reduce pain, fatigue, and sleep problems in people with multiple sclerosis (MS). Researchers enrolled 90 adults with MS who had moderate to severe pain and fatigue. Par…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Hasan Kalyoncu University • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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One spin to sharpen the mind: VR cycling shows promise for MS
Symptom relief CompletedThis study looked at whether a single session of moderate cycling with virtual reality could help people with multiple sclerosis (MS) think faster. 23 adults with MS and mild-to-moderate walking difficulty took part. They did a cycling workout while using different types of virtu…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Kessler Foundation • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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New combo therapy aims to boost daily life for brain disorder patients
Symptom relief CompletedThis study tested whether a program combining cognitive behavioral therapy, cognitive rehabilitation, and lifestyle coaching is practical and helpful for people with mild cognitive impairment, traumatic brain injury, multiple sclerosis, or long COVID. Fifteen participants receive…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Gratitude letters and happy memories: a new tool for newly diagnosed MS patients?
Symptom relief CompletedThis study tested whether a five-week program of positive psychology exercises—like writing a gratitude letter or recalling a past success—could help 30 people recently diagnosed with multiple sclerosis feel more hopeful and improve their emotional well-being and quality of life.…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Can a phone app help MS patients ease fatigue and pain at home?
Symptom relief CompletedThis study tested how easy and useful the MeTime MS app is for adults with multiple sclerosis who have fatigue and chronic pain. Ten participants used the app to guide them through either a relaxing or stimulating acupressure routine at home. After six weeks, researchers intervie…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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8-Week aerobic program boosts mobility in MS patients
Symptom relief CompletedThis study looked at whether an 8-week aerobic exercise program could improve movement and walking in 30 adults with multiple sclerosis (MS). Participants were randomly assigned to either an exercise group or a control group. The exercise group showed significant improvements in …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Lokman Hekim University • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Virtual rehab helps MS patients move better at home
Symptom relief CompletedThis study tested whether a home-based telerehabilitation system could help veterans with multiple sclerosis (MS) improve their balance and mobility. Fifty-one participants used a daily exercise diary and received remote monitoring of their strength and motor functions. The goal …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Zapping the brain to ease MS mental fog and mood
Symptom relief CompletedThis study tested whether repeated electrical brain stimulation could improve mental health and cognitive function in people with multiple sclerosis (MS). Fifty-three adults with MS received either real or fake stimulation in a double-blind setup. The researchers measured quality…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: The National Brain Mapping Laboratory (NBML) • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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Robot exoskeleton offers new hope for MS walking difficulties
Symptom relief CompletedThis study tested a self-balancing robotic exoskeleton called Atalante in 15 people with multiple sclerosis who have trouble walking. The goal was to see if the device is easy to use and safe. Participants used the exoskeleton for gait therapy, and researchers measured satisfacti…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Multiple Sclerosis Center of Catalonia • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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Smartphone app boosts strength in MS patients
Symptom relief CompletedThis study tested whether an artificial intelligence (AI) app could help people with multiple sclerosis (MS) do strength exercises at home better than traditional paper instructions. Fifty-eight adults with MS followed a 20-week exercise program. One group used an AI app that gav…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Cadiz • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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Can remote exercise ease MS symptoms? study compares live vs recorded workouts
Symptom relief CompletedThis study tested two types of remote exercise programs for people with relapsing-remitting multiple sclerosis. Sixteen participants did either live online classes or watched pre-recorded exercise videos. The goal was to see which method better improves walking, strength, fatigue…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Yeditepe University • Aim: Symptom relief
Last updated May 13, 2026 16:04 UTC
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Can a supplement beat MS fatigue? new study tests MitoQ
Symptom relief CompletedThis study looked at whether MitoQ, a dietary supplement, can help reduce fatigue in people with multiple sclerosis (MS). 45 participants with MS and significant fatigue took either MitoQ or a placebo daily for 12 weeks. The main goal was to see if MitoQ improved fatigue scores c…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1, PHASE2 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 13, 2026 16:00 UTC
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Remote workout program shows promise for Hispanics/Latinos battling MS
Symptom relief CompletedThis study tested a 4-month exercise program done at home for Hispanic/Latino adults with multiple sclerosis (MS). The goal was to see if it could improve physical function, reduce fatigue, and boost quality of life. Thirty-three participants worked with coaches via video calls. …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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Simple exercises may ease bladder problems in MS patients
Symptom relief CompletedThis study tested whether a special pelvic floor exercise program, based on the Health Belief Model, can help reduce urinary incontinence and improve quality of life in women with multiple sclerosis. 46 women participated, and researchers measured changes in incontinence severity…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Nurgül KAPLAN • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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MS patients share their shot experiences: kesimpta vs ocrevus
Symptom relief CompletedThis study looked at how people with multiple sclerosis felt about their first injection of either Kesimpta or a new under-the-skin version of Ocrevus. Researchers asked 134 adults about pain, redness, swelling, and itching at the injection site, as well as overall satisfaction. …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Novartis Pharmaceuticals • Aim: Symptom relief
Last updated May 12, 2026 13:42 UTC
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Can simple pelvic floor exercises ease bladder troubles for women with MS?
Symptom relief CompletedThis study tested whether pelvic floor exercises (strengthening, relaxation, or both) could help women with multiple sclerosis who have bladder control problems. Twenty-four women did the exercises at home with weekly online coaching for 8 weeks. The researchers measured changes …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Gazi University • Aim: Symptom relief
Last updated May 11, 2026 20:47 UTC
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Walking faster, feeling less tired: new exercise hope for MS
Symptom relief CompletedThis study looked at whether high-intensity walking exercise can reduce fatigue and improve walking in people with multiple sclerosis (MS). Twelve adults with MS who had walking difficulties and significant fatigue took part. The goal was to see if this type of exercise could hel…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated May 11, 2026 20:47 UTC
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New arabic app aims to boost MS Patients' quality of life
Symptom relief CompletedThis study tested whether an Arabic mobile app could help people with multiple sclerosis (MS) improve their self-care and quality of life. 74 adults with MS used the app or received usual care for 3 months. Researchers measured changes in self-care habits and well-being using sta…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated May 11, 2026 20:40 UTC
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Brain zaps and puzzles may sharpen MS minds
Symptom relief CompletedThis study tested whether a gentle brain stimulation technique (tDCS) combined with cognitive rehabilitation can improve memory, attention, and brain flexibility in people with multiple sclerosis. 45 adults with relapsing-remitting MS took part. The goal was to see if these treat…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Shahid Beheshti University of Medical Sciences • Aim: Symptom relief
Last updated May 11, 2026 20:40 UTC
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Can moving to music boost fitness in people with disabilities?
Symptom relief CompletedThis study tested a 12-week exercise program set to music for 108 adults with physical disabilities like spinal cord injury, stroke, or multiple sclerosis. Participants were randomly assigned to the music exercise group or a waitlist. The goal was to see if the program improved h…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated May 11, 2026 20:40 UTC
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MIND diet shows promise for easing MS fatigue and brain fog
Symptom relief CompletedThis study tested whether the MIND diet (a mix of the Mediterranean and DASH diets) can improve fatigue, brain fog, and quality of life in people with multiple sclerosis (MS). 62 adults with MS followed either the MIND diet or a standard healthy diet for 3 months. Researchers mea…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Betul Uner • Aim: Symptom relief
Last updated May 11, 2026 20:38 UTC
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Video workouts may loosen stiff legs in MS patients
Symptom relief CompletedThis study tested two different group exercise programs delivered by video call to help people with multiple sclerosis manage leg spasticity (muscle stiffness). 232 participants joined from home. The goal was to see which program better reduces spasticity and improves daily life.
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 08, 2026 12:00 UTC
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Pilates shows promise for improving balance in MS patients
Symptom relief CompletedThis study looked at whether two types of Pilates (mat and reformer) can help people with multiple sclerosis (MS) improve their balance, walking, and posture. Thirty adults with MS were randomly assigned to mat Pilates, reformer Pilates, or a control group. Both Pilates groups tr…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Gazi University • Aim: Symptom relief
Last updated May 06, 2026 16:04 UTC
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Probiotic drink trial for MS shows promise in small study
Symptom relief CompletedThis study tested whether people with multiple sclerosis (MS) could take a probiotic drink daily for 12 weeks and if they found it acceptable. 29 participants drank 70ml of the probiotic each day, completed online questionnaires about symptoms and quality of life, and provided st…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Sheffield Hallam University • Aim: Symptom relief
Last updated May 04, 2026 16:31 UTC
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Brain retraining shows promise for easing MS fatigue and pain
Symptom relief CompletedThis study tested whether a mind-body program called amygdala insula retraining, along with lifestyle changes, could improve symptoms in people with multiple sclerosis (MS). 132 adults with MS were assigned to either the program, a lifestyle-only group, or a waitlist. The main go…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Chronic Conditions Research Fund • Aim: Symptom relief
Last updated May 04, 2026 16:30 UTC
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Chill out: cryotherapy tested for MS fatigue
Symptom relief CompletedThis study looked at whether partial-body cryotherapy (brief exposure to extreme cold) can ease fatigue in people with multiple sclerosis during a rehabilitation stay. 43 adults with MS in remission took part. Researchers measured changes in fatigue, spasticity, and quality of li…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Fondation Ildys • Aim: Symptom relief
Last updated May 04, 2026 16:24 UTC
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Could bright light be the key to better sleep for MS patients?
Symptom relief CompletedThis study tested whether bright light therapy can improve sleep in people with multiple sclerosis (MS). 27 adults with MS and sleep problems used a bright light device to see if it helped them sleep better and feel more rested. The goal was to find a simple, drug-free way to eas…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 04, 2026 16:21 UTC
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Virtual reality hand training shows promise for MS patients
Symptom relief CompletedThis study tested whether watching 3D virtual reality videos of hand and arm movements could improve upper limb function in 32 people with multiple sclerosis who have frequent attacks. Participants had been diagnosed less than 2 years and had moderate disability. The training aim…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Abant Izzet Baysal University • Aim: Symptom relief
Last updated May 01, 2026 15:58 UTC
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Can a 6-Meter walk test replace the standard one for MS patients?
Knowledge-focused CompletedThis study looked at whether a 6-minute walk test done in a short 6-meter hallway works as well as the usual 30-meter version for people with multiple sclerosis. Twenty-one adults with MS took part. The goal was to see if the shorter version is reliable and gives similar results,…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Haute Ecole de Santé Vaud • Aim: Knowledge-focused
Last updated May 16, 2026 22:34 UTC
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Lockdowns worsened health habits in chronic disease patients, study finds
Knowledge-focused CompletedThis study examined how COVID-19 lockdowns changed health behaviors and medication use in over 1,300 people with chronic conditions like heart disease, multiple sclerosis, and macular degeneration. Researchers found that isolation, stress, and difficulty accessing care led to cha…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 16, 2026 22:33 UTC
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New study reveals how MS drug passes through breastmilk to babies
Knowledge-focused CompletedThis study looked at how much of the multiple sclerosis (MS) drug ocrelizumab gets into breastmilk and whether it affects babies' immune cells. Twenty-six breastfeeding women with MS or a first MS-like episode took part. Researchers measured drug levels in breastmilk and checked …
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Hoffmann-La Roche • Aim: Knowledge-focused
Last updated May 16, 2026 22:33 UTC
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Scientists uncover the secret behind your arm swing
Knowledge-focused CompletedThis study looked at why people swing their arms when they walk, especially in people with conditions like multiple sclerosis, stroke, or Parkinson's disease. Researchers had 25 participants walk on a special treadmill to measure how arm movement relates to body motion. The goal …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Istituto Auxologico Italiano • Aim: Knowledge-focused
Last updated May 16, 2026 22:32 UTC
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New computer test spots early brain fog in MS patients
Knowledge-focused CompletedThis study tested a short, computer-based thinking and memory test for people with multiple sclerosis (MS). The goal was to see if it could quickly spot early cognitive problems, like slow information processing and memory issues. Over 400 French-speaking adults with MS took the …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated May 16, 2026 22:31 UTC
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New clues in spinal fluid may predict MS years before symptoms
Knowledge-focused CompletedThis study looked at 100 people who have brain changes seen on MRI but no MS symptoms yet (called radiologically isolated syndrome). Researchers measured four substances in their spinal fluid and blood to see if any could predict who later develops multiple sclerosis. The goal is…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 16, 2026 22:31 UTC
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Scientists investigate immune cells in MS – no treatment involved
Knowledge-focused CompletedThis study examined a type of immune cell called 4BL B cells in 125 people with multiple sclerosis (MS) and compared them to healthy controls. The goal was to see if these cells are more common in MS and might contribute to inflammation. No treatment was given; the study was pure…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 16, 2026 22:30 UTC
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New risk score aims to predict multiple sclerosis before symptoms start
Knowledge-focused CompletedThis study tested a special risk score that combines genetic and environmental factors to see if it can predict who might develop multiple sclerosis (MS). Researchers studied 181 people, including those with MS and their close relatives. The goal was to improve understanding of M…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated May 16, 2026 22:30 UTC
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New bladder symptom tool tested in turkish MS patients
Knowledge-focused CompletedThis study checked if a bladder symptom questionnaire works well in Turkish for people with multiple sclerosis (MS). 71 adults with MS completed the questionnaire and another bladder survey. The goal was to make sure the tool accurately measures bladder problems in Turkish-speaki…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Kutahya Health Sciences University • Aim: Knowledge-focused
Last updated May 16, 2026 22:30 UTC
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MS fatigue mystery: scientists hunt for clues in immune cells
Knowledge-focused CompletedThis study looked at whether a certain type of immune cell (cytotoxic CD4+ T cells) is linked to fatigue in people with multiple sclerosis (MS). 34 adults with MS completed physical tasks and fatigue surveys, and researchers measured their immune cells. The goal was to better und…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated May 16, 2026 22:30 UTC
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MS drug access may vary by race and income, study finds
Knowledge-focused CompletedThis study looked at 800 multiple sclerosis patients to see if gender, race, or socioeconomic background affects how quickly they start Ocrelizumab treatment and how well it works. Researchers reviewed medical records from two large hospitals over four years. The goal is to ident…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 16, 2026 22:30 UTC
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Libya MS study reveals gaps in diagnosis and treatment access
Knowledge-focused CompletedThis study looked at how quickly people with multiple sclerosis (MS) in Libya get diagnosed and treated, and how that affects their disability. Researchers reviewed data from 369 adults with MS at two hospitals. The goal is to find gaps in care and improve services for patients i…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University of Zintan • Aim: Knowledge-focused
Last updated May 16, 2026 22:30 UTC
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MS study reveals hidden link between brain and movement
Knowledge-focused CompletedThis study looked at how thinking and emotional difficulties impact the way people with multiple sclerosis (MS) look around and start walking. Researchers compared MS patients with and without these neuropsychological issues. They measured walking patterns, eye movements, and obs…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Lille Catholic University • Aim: Knowledge-focused
Last updated May 16, 2026 22:30 UTC
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Could a serotonin receptor help us understand multiple sclerosis?
Knowledge-focused CompletedThis study looked at whether a serotonin receptor called 5-HT7 could serve as a biomarker for multiple sclerosis (MS). Researchers measured the receptor on immune cells in blood samples from 100 people, including healthy volunteers and MS patients on stable treatment. The goal wa…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Centre Hospitalier Régional d'Orléans • Aim: Knowledge-focused
Last updated May 16, 2026 22:29 UTC
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Brain scans reveal clues to MS fatigue mystery
Knowledge-focused CompletedThis study looked at 10 people with multiple sclerosis to understand why they feel tired. Researchers used special brain scans to measure inflammation and chemical activity. They did not test any new treatments. The goal was to learn more about what causes MS-related fatigue.
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1, PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 16, 2026 22:28 UTC
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Healthy men test drug interactions for MS treatment
Knowledge-focused CompletedThis study looked at how two common drugs, gemfibrozil and rifampicin, change the way the body processes a multiple sclerosis medicine called SAR442168. Thirty healthy men aged 18 to 45 took part. The goal was to gather information, not to treat any disease.
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1 • Sponsor: Sanofi • Aim: Knowledge-focused
Last updated May 16, 2026 22:28 UTC
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New walking test could help MS patients track balance and thinking
Knowledge-focused CompletedThis study tested a walking test called the L test in 50 people with multiple sclerosis. The test measures walking speed and balance while also doing a thinking task. The goal was to see if the L test is a reliable way to check how MS affects walking and thinking at the same time…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Sanko University • Aim: Knowledge-focused
Last updated May 16, 2026 22:28 UTC
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MS fatigue study digs deeper: can we measure it better?
Knowledge-focused CompletedThis study looked at fatigue in 60 people with relapsing-remitting multiple sclerosis. Researchers compared standard questionnaires (where patients rate their fatigue) with objective tests like walking speed, hand grip strength, and balance measurements. The goal was to see if th…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Asli Demirtaş • Aim: Knowledge-focused
Last updated May 16, 2026 22:28 UTC
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MS Drug's immune cell effects revealed in small study
Knowledge-focused CompletedThis study looked at how oral cladribine changes different types of immune cells in the blood and spinal fluid of 10 people with relapsing-remitting multiple sclerosis over 96 weeks. Researchers measured changes in B cells, T cells, and plasma cells to understand the drug's effec…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated May 16, 2026 22:27 UTC
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Tiny sensors could reveal hidden walking troubles in early MS
Knowledge-focused CompletedThis study tested whether small wearable motion sensors can detect early walking and balance issues in people with multiple sclerosis (MS). Researchers compared 70 participants (MS patients and healthy volunteers) as they walked and performed balance tasks. The goal was to see if…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Lille Catholic University • Aim: Knowledge-focused
Last updated May 16, 2026 22:27 UTC
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MS Drug's journey through the body revealed in small study
Knowledge-focused CompletedThis study looked at how healthy men absorb, process, and eliminate a new multiple sclerosis drug called SAR442168. Six men took a single dose, and researchers measured how much of the drug left their body in urine and stool. The goal was to understand the drug's metabolism and s…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1 • Sponsor: Sanofi • Aim: Knowledge-focused
Last updated May 16, 2026 22:26 UTC
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New tools aim to spot nerve damage early in MS
Knowledge-focused CompletedThis study followed 134 people who had a first episode of neurological symptoms (clinically isolated syndrome) that could lead to multiple sclerosis. Researchers used MRI scans and eye exams to detect and track nerve damage over time. The goal was to develop better ways to predic…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 16, 2026 22:26 UTC
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New MRI comparison aims to sharpen multiple sclerosis detection
Knowledge-focused CompletedThis study tested two different MRI scan methods to see how well they find a specific sign of multiple sclerosis (MS) called the central vein sign. Researchers compared a standard scan with an optimized version in 60 adults with early-stage MS. The goal was to improve how doctors…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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MS study reveals link between muscle loss and breathing problems
Knowledge-focused CompletedThis study examined the connection between muscle loss (sarcopenia) and breathing function in 40 people with multiple sclerosis. Participants completed breathing strength tests and spirometry in a single session. The goal was to understand if muscle structure relates to respirato…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Uskudar University • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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MS Patients' ability to spot joy and kindness under the microscope
Knowledge-focused CompletedThis study looked at whether people with multiple sclerosis (MS) can recognize positive emotions as well as healthy individuals. Researchers compared 101 participants—some with MS and some without—using emotion recognition tests. The goal was to understand if positive emotion rec…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Lille Catholic University • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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MRI showdown: which scan best reveals MS activity?
Knowledge-focused CompletedThis study tested two different MRI techniques to see which one better detects active brain lesions in people with multiple sclerosis (MS). 180 adults with MS or similar conditions had brain scans after a recent symptom flare-up. The goal was to find the most sensitive method for…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Sleep quality linked to fatigue and function in MS patients
Knowledge-focused CompletedThis study looked at 102 people with multiple sclerosis to see how sleep quality relates to fatigue, body awareness, and the ability to use arms and legs. Participants were grouped by good or poor sleep, then tested on tasks like walking, pegboard tests, and heartbeat counting. T…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Gulhane School of Medicine • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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MS and fertility: new study explores hidden impact on ovarian health
Knowledge-focused CompletedThis study looked at whether multiple sclerosis (MS) and its treatments affect a woman's egg supply, measured by a hormone called AMH. Researchers analyzed blood samples from over 800 women with MS or a related condition, aged 18 to 35. The goal was to help doctors decide when to…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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New study reveals psychological secrets to thriving after MS diagnosis
Knowledge-focused CompletedThis study looked at 361 people recently diagnosed with multiple sclerosis to understand how mindfulness and 'flow' (being fully absorbed in an activity) relate to their mental health. Participants filled out questionnaires about their well-being, anxiety, and depression at the s…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Marta Bassi • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Iron nanoparticle could light up brain inflammation on MRI
Knowledge-focused CompletedThis study looked at whether ferumoxytol, an iron-based contrast agent, can help spot inflammation in the brains of people with multiple sclerosis (MS) using a powerful 7 Tesla MRI. Fourteen participants (some with MS, some healthy) received ferumoxytol and had multiple MRI scans…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1 • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Spinal fluid clues may unlock MS mysteries
Knowledge-focused CompletedThis study looked at whether proteins in spinal fluid can reliably tell the difference between multiple sclerosis (MS) and other brain diseases, and also predict how MS will progress. Researchers analyzed fluid samples from 161 people with MS and compared them to standard clinica…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Gene study reveals how MS drug works in chinese patients
Knowledge-focused CompletedThis study looked at how a specific gene change (ABCG2 mutation) affects the amount of the MS drug teriflunomide in the body and its safety. 82 Chinese adults with relapsing multiple sclerosis took the drug once daily for 24 weeks. Researchers measured drug levels and tracked sid…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Sanofi • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Personalized diet advice tested for MS patients
Knowledge-focused CompletedThis study looked at whether personalized dietary advice from a dietitian helps people with multiple sclerosis (MS) increase their calcium intake compared to just receiving a standard information sheet. A total of 182 MS patients who could walk and had never had a diet consultati…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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VR workouts vs. standard exercise: which is safer for MS patients?
Knowledge-focused CompletedThis study looked at how different types of exercise—standard, conservative aerobic, and virtual reality-based aerobic—affect brain activity, body temperature, and fatigue in people with multiple sclerosis. Twelve adults with relapsing-remitting MS completed three exercise sessio…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Acibadem University • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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New test tracks immune response to MS drug in small study
Knowledge-focused CompletedThis study involved 15 people with multiple sclerosis who were already taking the drug alemtuzumab. Researchers wanted to see if the body makes antibodies against the drug and how those antibodies change over 24 months. The goal was to learn more about how these antibodies might …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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MS and menstrual cycles: new study reveals exercise response differences
Knowledge-focused CompletedThis study looked at how women with multiple sclerosis (MS) feel about and respond to exercise at different times of their menstrual cycle. Fifteen women with MS and fifteen without did high-intensity interval training and strength training sessions. Researchers measured satisfac…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Universidad de Almeria • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Vaccine shield tested: do immunocompromised patients get enough protection?
Knowledge-focused CompletedThis study looked at how well the Pfizer COVID-19 vaccine works in adults with weakened immune systems (like kidney transplant patients, people with cancer, or those on dialysis) compared to healthy adults. Researchers measured antibody levels and their ability to neutralize the …
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Centre Hospitalier Régional d'Orléans • Aim: Knowledge-focused
Last updated May 13, 2026 16:03 UTC
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Eye camera reveals hidden clues to multiple sclerosis progression
Knowledge-focused CompletedThis study tested a special eye-imaging technique called adaptive optics to look at blood vessel changes in the retina of people with multiple sclerosis (MS). Researchers measured swelling around retinal vessels in 50 participants with different MS types and compared them to heal…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC
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Patch vs. pill: new ozanimod skin patch tested in healthy volunteers
Knowledge-focused CompletedThis study tested whether a skin patch (transdermal delivery system) can deliver the drug ozanimod as well as the oral capsule (Zeposia) in 24 healthy adults. Participants either took one capsule or wore a patch for 7 days. Researchers measured drug levels in the blood and checke…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Corium Innovations, Inc. • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC
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Scientists dive deep into Cladribine's immune effects in MS
Knowledge-focused CompletedThis study looked at how the drug cladribine affects the immune system in people with multiple sclerosis (MS). Researchers analyzed blood samples from 77 participants, including healthy donors and MS patients at different stages. The goal was to better understand the drug's anti-…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC
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Pregnancy and MS: new study tracks moms and babies for three years
Knowledge-focused CompletedThis study followed 168 women with Multiple Sclerosis who were pregnant or planning pregnancy. Researchers conducted phone interviews every three months during pregnancy and tracked babies' growth for up to three years after birth. The goal was to understand how MS and its treatm…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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Eye-Tracking AI may spot MS severity without needles
Knowledge-focused CompletedThis study involved 200 adults with multiple sclerosis (MS) who completed eye-tracking tasks. Researchers used the data to train computer programs to identify which eye-movement patterns best reflect MS severity and thinking abilities. The goal was to develop a non-invasive, easy…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Innodem Neurosciences • Aim: Knowledge-focused
Last updated May 12, 2026 13:44 UTC
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Blood tests may reveal if atypical MS is a different disease
Knowledge-focused CompletedThis study looked at 58 people, including those with typical and atypical multiple sclerosis (MS) and healthy controls, to see if blood markers of nerve damage could help tell these conditions apart. Researchers measured two proteins in the blood: neurofilament light chain and GF…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated May 11, 2026 20:53 UTC
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Severe MS Patients' breathing troubles revealed in new study
Knowledge-focused CompletedThis study looked at breathing problems in 70 people with severe multiple sclerosis (MS). Researchers measured how well the breathing muscles work and tested lung function. The goal was to better understand these issues, not to test a new treatment.
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC
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MS and depression: can you still read emotions?
Knowledge-focused CompletedThis study looked at whether depression makes it harder for people with multiple sclerosis (MS) to recognize emotions like anger, joy, or neutral expressions on faces. Researchers tested 38 participants, including MS patients and healthy controls, using facial expression tasks an…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Lille Catholic University • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC
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MS safety knowledge put to the test: survey reveals how well patients and doctors understand mayzent
Knowledge-focused CompletedThis study surveyed 335 healthcare professionals and MS patients/caregivers in Europe to see if they understood the safety steps for using Mayzent (siponimod). Participants answered questions about proper use, side effects, and risks. The goal was to measure knowledge and identif…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated May 08, 2026 12:01 UTC
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Pandemic's hidden toll: MS relapse care under scrutiny
Knowledge-focused CompletedThis study looked at how the COVID-19 pandemic changed the way multiple sclerosis (MS) relapses were reported and managed. Researchers compared 51 patients who had a relapse during the first wave of the pandemic (April-June 2020) to those who had a relapse during the same months …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Nottingham University Hospitals NHS Trust • Aim: Knowledge-focused
Last updated May 07, 2026 18:43 UTC
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Tailored walking therapy shows promise for spinal cord patients
Knowledge-focused CompletedThis study tested whether personalized walking training based on detailed 3D movement analysis works better than standard walking therapy for people with spinal cord damage from injury or multiple sclerosis. 63 participants received either training tailored to their specific walk…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated May 05, 2026 11:54 UTC
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MS drug in pregnancy: what happens to Baby's immune cells?
Knowledge-focused CompletedThis study looked at 70 pregnant women with multiple sclerosis or clinically isolated syndrome who took the drug ocrelizumab before or during early pregnancy. Researchers measured B cell levels in their babies to see if the drug crossed the placenta. The goal was to gather safety…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Hoffmann-La Roche • Aim: Knowledge-focused
Last updated May 05, 2026 11:54 UTC
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Gene hunt: why some MS patients get liver damage from common drug
Knowledge-focused CompletedThis study looked at 300 people with multiple sclerosis (MS) to see if certain genes make some patients more likely to develop liver injury from the drug beta-interferon. Researchers compared those who had liver problems to those who did not. The goal was to find genetic clues th…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated May 04, 2026 16:19 UTC
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New models could help robots assist stroke and MS patients based on their own muscle strength
Knowledge-focused CompletedThis study involved 32 people with arm weakness from stroke, multiple sclerosis, or spinal cord injury. Researchers measured how much force each person could voluntarily produce in their arm muscles. They used this data to create mathematical models that predict a person's remain…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Pôle Saint Hélier • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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Scientists engineer 'smarter' IL-2 to tame overactive immune systems
Knowledge-focused CompletedThis study tested specially engineered versions of a natural immune protein (IL-2) in blood samples from 67 people with autoimmune or inflammatory diseases like lupus, multiple sclerosis, and rheumatoid arthritis. The goal was to see if these modified proteins could selectively a…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Apr 24, 2026 16:18 UTC
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Eyes could reveal hidden MS damage in new tech study
Knowledge-focused CompletedThis study aims to find out if tracking a person's eye movements can serve as a reliable marker for how severe their multiple sclerosis (MS) is and how it affects their thinking. Researchers enrolled 120 adults with MS to record their eye movements and compare them with standard …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Innodem Neurosciences • Aim: Knowledge-focused
Last updated Apr 20, 2026 16:19 UTC