Gold nanoparticles tested as brain energy boost for MS
NCT ID NCT03993171
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tested a liquid suspension of gold nanocrystals, called CNM-Au8, in 33 people with relapsing multiple sclerosis. The goal was to see if the treatment could improve energy metabolism in brain cells, measured by a special MRI scan. Participants took the drug by mouth for 12 weeks while continuing their usual MS medication. The study looked at safety and changes in brain chemistry, not directly at symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- gold nanocrystals (CNM-Au8)
- What this could lead to
- If it works, this could point toward a new way to support brain cell energy in multiple sclerosis, potentially slowing disease progression.
- What could go wrong
- This is a small, early-phase trial with only 33 participants, so results may not apply to everyone. The study focused on brain chemistry changes, not direct symptom improvement, and the treatment may not show clear benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Texas Southwestern
Dallas, Texas, 75390, United States
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