MS drug during pregnancy: what happens to Baby's immune cells?
NCT ID NCT04998812
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study checked how the multiple sclerosis drug ocrelizumab passes from mother to baby during pregnancy. Researchers measured B cell levels in 70 infants whose mothers took the drug around the time of pregnancy. The goal was to see if the drug affects the baby's immune system at birth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ocrelizumab
What this could lead to
If successful, this could help doctors understand the safety of ocrelizumab during pregnancy and guide treatment decisions for women with MS.
What could go wrong
This is a small, completed observational study, not a treatment trial. It only measures effects, not outcomes, so it cannot prove safety or harm definitively.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hopital Pierre Wertheimer - Hopital Neurologique
Bron, 69003, France
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Hosp. Clinico San Carlos
Madrid, 28040, Spain
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Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Hôpital de la Pitié Salpétrière
Paris, 75013, France
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Inselspital Bern
Bern, 3010, Switzerland
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MultipEL Studies - Institut für klinische Studien
Hamburg, 22179, Germany
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St. Josef Hospital GmbH
Bochum, 44791, Germany
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The Ken and Ruth Davee department of Neurology
Chicago, Illinois, 60611-4296, United States
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University Of Colorado
Aurora, Colorado, 80045, United States
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University of California San Francisco
San Francisco, California, 94158, United States
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Universitätsspital Basel
Basel, 4031, Switzerland