Gene test could personalize MS drug dosing
NCT ID NCT04410965
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at how a common gene mutation (ABCG2) affects the levels and side effects of the MS drug teriflunomide in 82 Chinese patients. Participants took teriflunomide 14 mg daily for 24 weeks. The goal was to see if the mutation changes drug exposure and safety, which could help tailor treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
teriflunomide
What this could lead to
If successful, this could help doctors personalize teriflunomide dosing for Chinese MS patients based on their genetics, potentially improving safety.
What could go wrong
This is a small, completed Phase 4 study focused on genetic effects, not a new treatment. The results may not apply to other populations or change current practice.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Investigational Site Number
China, China