Can genes predict liver damage from MS drug?

NCT ID NCT01118130

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study enrolled 300 people with multiple sclerosis who were taking beta-interferon. Researchers compared the genes of those who developed liver injury to those who did not, aiming to find genetic markers that predict this side effect. No new drug or treatment was tested.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors predict which MS patients are at risk for liver damage from beta-interferon, leading to safer prescribing.

What could go wrong

This is an observational study, not a treatment trial. It only looks for genetic links, so it won't directly change care. Results may not apply to all MS patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dalhousie MS Research Unit

    Halifax, Nova Scotia, Canada

  • Hôpital Notre-Dame MS clinic

    Montreal, Quebec, Canada

  • London Health Sciences Centre MS clinic

    London, Ontario, Canada

  • MS Clinic UBC Hospital

    Vancouver, British Columbia, V6T 2B5, Canada

  • Winnipeg Health Sciences Centre

    Winnipeg, Manitoba, Canada