Can gabapentin or memantine stop the shakes in MS eyes?
NCT ID NCT01744444
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested two drugs, gabapentin and memantine, in 10 people with multiple sclerosis who have a constant eye shaking called pendular nystagmus. The goal was to see if either drug could reduce the eye movement and improve vision and quality of life. Each person tried both drugs in a random order, and the researchers measured eye speed, clarity of sight, and how bothersome the shaking felt.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
gabapentin and memantine
What this could lead to
If it works, this could point toward a treatment to calm eye shaking and improve vision in people with multiple sclerosis.
What could go wrong
This is a very small, early-phase trial with only 10 participants, so results may not apply to everyone. The drugs may cause side effects or not improve symptoms significantly.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hôpital Neurologique Unité de Neuro-Ophtalmologie
Bron, 69677, France