COVID - 19

This study tested two types of short digital messages to see if they could encourage COVID-19 vaccination in adults with anxiety or depression. Over 1,400 undervaccinated participants received either standard public health messages, messages designed to build resistance to misinf…

This large study tested whether giving extra doses (boosters) of the Pfizer-BioNTech COVID-19 vaccine to healthy people who already had the vaccine was safe and helped prevent COVID-19. Over 16,000 people took part, and the study looked at different booster schedules and doses. T…

This early-stage trial tested a new COVID-19 booster vaccine given as a nasal spray. The goal was to see if it is safe and how well it boosts the immune system. The study involved 60 healthy adults who had already received the standard COVID-19 shots. Researchers monitored side e…

This study tested updated versions of the Pfizer-BioNTech COVID-19 vaccine in over 1,400 healthy people who had already received prior COVID-19 vaccines. Participants received a single booster dose of one of several new vaccine formulas designed to target newer virus variants. Th…

This study tested a new type of COVID-19 vaccine (ARCT-2303) in over 1,500 adults who had already received a COVID-19 vaccine. Some participants got the COVID vaccine and the flu shot at the same time, while others got the COVID vaccine alone. The goal was to see how well the vac…

This study tested a new COVID-19 vaccine made using CHO cells in healthy people aged 3 and older. About 3100 participants received either the vaccine or a placebo to check safety and immune response. The goal was to find the best dose and schedule for different age groups.

This study tested new COVID-19 mRNA booster vaccines in 692 healthy adults who had already received their primary vaccine series. The goal was to see how well the boosters boosted immunity and whether they were safe. Participants received either an experimental vaccine or a contr…

This study looked at whether the SpikoGen vaccine works well as a booster (3rd or 4th dose) for adults who already had a COVID-19 vaccine. 81 adults received one shot, and researchers measured their immune response and any side effects. The goal was to see if SpikoGen could boost…

This study tested whether a single injection combining a licensed COVID-19 vaccine and a licensed flu vaccine is safe and triggers a strong immune response. It involved 644 healthy adults aged 50 and older. The main goal was to check for side effects and measure antibody levels a…

This study tested an experimental vaccine called VBI-2901a in 103 healthy adults aged 18-64 who had already received a COVID-19 vaccine. The vaccine targets three coronaviruses: SARS-CoV-2 (COVID-19), SARS-CoV-1, and MERS-CoV. The goal was to check safety and see if it boosts the…

This study tested updated COVID-19 vaccines designed to protect against new and emerging virus variants. About 1,270 adults who had already been vaccinated received one or two doses of these variant-specific vaccines. The goal was to see how well the updated vaccines boost the im…

This study tested a new combination vaccine (mRNA-1083) that targets both COVID-19 and influenza in one shot. It involved 2,457 healthy adults aged 50 and older in Japan, Taiwan, and South Korea. The goal was to see how well the vaccine triggers an immune response and to check fo…

This study tested whether showing a short video or asking a simple question in the emergency department could encourage adults to get a COVID-19 booster shot. Over 900 people took part, and researchers tracked who got vaccinated within 30 days. The goal was to find easy ways to i…

This study looked at whether a recombinant COVID-19 booster vaccine can strengthen the immune response in people with weakened immune systems, specifically those with inflammatory bowel disease (IBD) or who have had an organ transplant. Researchers measured antibody levels before…

This early-stage study tested three new self-amplifying RNA vaccines against COVID-19 in 72 healthy adults, some already vaccinated and some not. The main goal was to check safety and how well the vaccines triggered an immune response. Results help researchers decide which vaccin…

This study tested a new mRNA vaccine that combines protection against seasonal flu and COVID-19 in a single shot. It involved 106 healthy adults aged 18-64 to check for side effects and immune response. The flu and COVID-19 parts had been tested separately before, and this was th…

This study tested a new booster vaccine called Covigenix VAX-002 in 46 healthy adults aged 18 and older. The vaccine uses DNA technology to target newer Omicron variants of the virus that causes COVID-19. The goal was to check if the booster is safe and helps the body build a str…

This study tested the CoviVac vaccine in 200 adults aged 60 and older to see if it safely prevents COVID-19. Researchers measured side effects and immune response after two doses. The goal was to check if the vaccine works well for older adults, who are at higher risk from the vi…

This study tested three different batches of the Novavax COVID-19 vaccine to make sure they all work the same. About 900 adults aged 18 to 49 who had already been vaccinated took part. Researchers measured their immune response and checked for safety issues.

This study tested the safety and immune response of different COVID-19 booster vaccines in about 1,900 people aged 12 to 64 in Kenya, Democratic Republic of Congo, and Rwanda. It included both people with and without HIV. The goal was to see if mixing vaccine types (like using on…

This study tested updated mRNA vaccines designed to protect against new SARS-CoV-2 variants (like XBB.1.5, JN.1, and KP.2). About 1,051 healthy people aged 12 and older received a single shot. Researchers monitored side effects and measured immune responses for six months to see …

This study tested the safety and immune response of Sanofi's experimental COVID-19 vaccines in over 3,000 adults aged 18 and older. Participants received either a two-dose primary series or a booster shot. The vaccines use a protein-based approach with an adjuvant to strengthen t…

This study tested a protein-based COVID-19 vaccine called SpikoGen in 39 adults who had never received a COVID-19 vaccine. Participants got two doses one month apart, followed by a third booster dose either one or three months later. The goal was to see how well the vaccine trigg…

This study tested a new COVID-19 booster vaccine called SpiN-Tec in 432 healthy adults aged 18 to 85 who had already received their full COVID-19 vaccination. The goal was to check if the vaccine is safe and boosts the immune system as well as or better than existing boosters. Th…

This large study tested the safety and effectiveness of the Pfizer-BioNTech mRNA vaccine (BNT162b2) in nearly 47,000 healthy volunteers aged 12 and older. Participants received two doses of the vaccine or a placebo, and the trial showed the vaccine was highly effective at prevent…

This study tested a single combined vaccine that aims to protect against both COVID-19 and influenza. About 8,800 healthy adults received either the combo shot or separate vaccines. Researchers monitored safety and immune responses for 6 months to see if the combined approach is …

This early-stage trial tested a new RNA-based COVID-19 booster vaccine in 383 healthy adults who had already received a COVID-19 vaccine. The main goal was to see if the vaccine was safe and to find the best dose. Researchers measured side effects and immune responses after one o…

This study looked at whether a smaller (fractional) dose of the Pfizer-BioNTech COVID-19 booster works as well as the standard dose. It involved 601 healthy adults in Mongolia who had already received two doses of Sinopharm, AstraZeneca, or Sputnik vaccines 6 to 9 months earlier.…

This study tested how well two updated COVID-19 vaccines (Novavax and Pfizer mRNA) protect adults from getting sick. About 1,188 people who had already received at least two mRNA vaccine doses took part. Participants were randomly assigned to get either the Novavax or Pfizer vacc…

This study tested how well the Moderna COVID-19 vaccine worked in adults with a higher risk of severe illness, including people living with HIV. Over 14,000 participants in Eastern and Southern Africa received either two or three doses, depending on whether they had a prior COVID…

This study tested a new COVID-19 booster vaccine called PHH-1V. Researchers compared it to the Pfizer booster shot in adults who were already fully vaccinated. The goal was to see if the new vaccine was as safe and effective at triggering an immune response, including against new…

This early-phase study tested whether high doses of vitamin E (alpha-tocopherol) could reduce C-reactive protein (CRP), a marker of inflammation, in 56 adults with COVID-19. The results suggest that vitamin E supplementation may significantly lower CRP levels. The study aimed to …

This study tested whether colchicine, an inexpensive anti-inflammatory drug usually used for gout, can help patients with mild to moderate COVID-19 pneumonia. 66 patients in Lahore were given the drug to see if it shortens hospital stays and reduces the need for oxygen. The goal …

This study tested whether giving a drug called abatacept early in the hospital stay helps COVID-19 patients on low-flow oxygen recover faster. 285 adults took part. The drug aims to calm an overactive immune response. Results compare recovery time and death rates between the drug…

This study tested whether two common blood pressure medicines (ACE inhibitors or ARBs) could help high-risk COVID-19 patients avoid intensive care, a ventilator, or death. About 372 adults with COVID-19 and heart disease risk factors took part. Researchers tracked outcomes like I…

This early-stage study tested a new oral drug called MSP008-22 in 64 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo, and researchers monitored for side effects. The goal was not to treat COVID-19 but to gather…

This study tested whether adding pegylated interferon lambda to standard care helps hospitalized COVID-19 patients recover faster. Nine adults with mild to moderate symptoms were randomly assigned to receive either the drug plus standard care or standard care alone. The main goal…

This study tested an experimental antiviral drug called S-892216 in 282 adults with mild-to-moderate COVID-19. The goal was to see if the drug could lower the amount of virus in the nose and throat faster than a placebo. Participants had to have symptoms and a positive test for t…

This completed Phase 2 trial tested combinations of drugs in people with COVID-19. Only 4 people took part. The goal was to see if the drugs helped patients recover faster and lower the risk of death. The study used a flexible master protocol to guide both hospital and home treat…

This study tested a treatment made from horse antibodies (INM005) in 243 adults hospitalized with moderate to severe COVID-19. The goal was to see if it helped patients get better within 28 days, using a standard scale of illness severity. The treatment aims to control the diseas…

This study collected CT scan images from over 10,000 adults to find better ways to diagnose COVID-19 and predict how severe the disease might become. Researchers used these images to develop computer programs that can help doctors identify the virus and estimate a patient's risk …

This study tested two quick triage tests—CAD4TB software that analyzes chest X-rays and a C-reactive protein blood test—to see how accurately they can rule out pulmonary tuberculosis in adults with symptoms like cough or fever. Researchers enrolled 1,400 participants in Lesotho a…

This study checked if a new rapid test can correctly detect Flu A, Flu B, COVID-19, and RSV from a nasal swab. Over 1,100 people with respiratory symptoms provided samples, which were compared to standard lab tests. The goal was to see how accurate the test is for over-the-counte…

This study looked at whether testing saliva (spit) is as good as the standard nose swab for finding COVID-19. Over 5,000 people provided both a nose swab and a saliva sample. The goal was to see if saliva testing could make screening easier and more comfortable while still being …

This study tested 949 adults with COVID-19 symptoms to see how well different test methods detect the virus. Researchers compared PCR and rapid antigen tests using both saliva and nasopharyngeal swabs. The goal was to find which combination is easiest and most accurate for widesp…

This study checked how well a new test called VitaSIRO solo™ detects COVID-19, flu, and RSV from nose swabs. Over 1,200 people with cold or flu symptoms took part. The test was compared to standard lab tests to see if it is accurate and reliable.

This study checked how well a new rapid test (iHealth COVID-19/Flu A&B) can detect COVID-19 and flu A&B in people with respiratory symptoms. 588 people with two or more symptoms (like fever, cough, or sore throat) gave nose swabs for the test and a standard lab test. The goal was…

This study tested a new, non-invasive method to detect COVID-19 by scanning a person's fingerprints. Researchers used a special camera to analyze sweat on the fingertips of 66 adults who had recently tested positive or negative for COVID-19. The goal was to see if patterns in swe…

This study tested whether taking a moderate dose of vitamin D (4,000 IU daily) could lower the chance of getting COVID-19 compared to a low dose (400 IU daily). Over 2,000 adults from the Chicago area and other US communities took part. Participants reported any COVID-19 infectio…

This study tested whether a dietary supplement called Mito-MES could prevent severe viral infections, like COVID-19, in adults who had close contact with someone sick. 80 healthy adults who were exposed to a person with respiratory symptoms took the supplement or served as contro…

This study tested whether taking a daily vitamin D3 supplement for 4 weeks could help people recently diagnosed with COVID-19 feel less sick and avoid needing doctor visits or hospital care. It also looked at whether the same supplement could protect their household members from …

This study looked at the safety of a drug called Dimolegin in preventing dangerous blood clots in adults hospitalized with moderate COVID-19. A total of 184 patients took the medicine once daily as part of their regular care. Researchers tracked bleeding events and other side eff…

This study tested whether five infusions of stem cells (HB-adMSCs) could prevent COVID-19 symptoms and hospitalizations in 53 high-risk workers like doctors and firefighters. Participants had no signs of COVID-19 at the start. The goal was to see if the stem cells could boost the…

This study tested whether five infusions of a person's own fat-derived stem cells could help prevent COVID-19 symptoms and hospital stays. It included 51 adults at high risk due to age, health conditions, or healthcare work. Participants had already stored their stem cells at the…

This study tested ways to increase COVID-19 vaccination rates among pregnant women, who face higher risks of severe illness and pregnancy complications from the virus. Over 6,900 participants from OB/GYN offices took part. The goal was to see if changes in clinic practices could …

This study tested a drug called thymalfasin (Ta1) to see if it could prevent COVID-19 infection in people with kidney failure who are on dialysis. These patients are at high risk because they spend time in dialysis centers and often have weak immune systems. The study involved 18…

This study tested whether a treatment called IMM-101 could help prevent severe respiratory infections, including COVID-19, in people with cancer. About 195 cancer patients at higher risk for severe COVID were randomly assigned to receive IMM-101 or just be observed. The goal was …

This study looked at whether lupus patients already taking hydroxychloroquine were less likely to catch or get severely ill from COVID-19. Researchers compared 552 patients who were either on or off the drug. The goal was to see if the medication offered any protection during the…

This study looked at whether a second booster (fourth dose) of the COVID-19 vaccine helps prevent serious illness in people aged 60 and older. Researchers tracked hospitalizations, deaths, and side effects in about 260 participants from Brazil. They also measured immune responses…

This pilot study tested whether a breathing exercise program can reduce persistent breathlessness in people with long COVID. 40 adults who had COVID-19 and still felt short of breath for more than 12 weeks took part. The study compared the breathing intervention to usual care to …

This study looked at whether the antiviral drug remdesivir can reduce symptoms of Long COVID. 73 adults with confirmed Long COVID received the drug for five days, and researchers checked their symptoms and health before and after treatment. The main goal was to see if this approa…

This study tested whether a daily breathing muscle training program could help adults with long COVID who have weak breathing muscles. 44 participants did breathing exercises twice a day for 8 weeks, combined with physical exercise. The goal was to see if this improved their lung…

This study tested a non-invasive radiofrequency treatment to help people with ongoing breathing issues after COVID-19. 96 adults who had COVID-19 and still had cough, shortness of breath, or fatigue for over a month took part. The treatment uses gentle radio waves to stimulate ti…

This study looked at whether lying face down (prone positioning) helps hospitalized COVID-19 patients who have low oxygen levels but are not able to use a breathing machine. About 600 adults took part. The goal was to see if this simple position change could lower the chance of d…

This study tested whether having COVID-19 patients with serious breathing problems lie face down (prone position) while receiving high-flow oxygen could reduce the need for breathing tubes and intensive care. Researchers enrolled 405 adults with COVID-19 pneumonia and acute respi…

This study tested whether a home-based exercise program, supported by video or phone calls, could help 20 severe COVID-19 survivors improve their walking, strength, and quality of life. Participants in the program received regular check-ins from a therapist, while the usual care …

This study tested whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) helps moderate to severe COVID-19 patients who need extra oxygen. Thirty adults with risk factors like diabetes or heart disease took part. Researchers measured oxygen levels, inf…

This study tested a short, on-site mindfulness program for 1,000 frontline healthcare workers in a Madrid hospital during the COVID-19 outbreak. The goal was to see if it helped reduce stress and was safe and easy to use. Participants rated how helpful it was on a scale from 0 to…

This study tested whether two months of daily smell training can help people who lost their sense of smell or taste due to COVID-19. Forty adults from a hospital in Guadeloupe took part. One group did smell exercises with different scents, while the other group did not. The resea…

This study looked at whether a 6-week breathing exercise program (inspiratory muscle training) can improve diaphragm strength and reduce shortness of breath in people who had COVID-19 and still feel breathless. 18 adults with confirmed diaphragm weakness participated. The goal wa…

This study tested whether a simple home program of breathing exercises and daily walking (at least 6000 steps) could ease long COVID symptoms like cough, shortness of breath, and fatigue. Forty adults with long COVID followed the program for six weeks. Researchers tracked symptom…

This study tested whether a smartphone app called Ghostly can help hospitalized patients—including those recovering from stroke, COVID-19, or frailty—regain muscle strength. Fifteen participants used the app for guided strength exercises, and researchers measured changes in muscl…

This study tested whether an e-health tool (like an app) could help adults who had COVID-19 and still felt tired or out of shape. 77 people took part, using the tool to guide and track their exercise. The goal was to see if it was easy to use and if it improved fitness and qualit…

This study followed 917 adults who had COVID-19 and were prescribed Paxlovid to see how often the virus comes back after treatment. Participants tested themselves at home after finishing the 5-day course. The goal was to learn more about Paxlovid rebound, not to test a new treatm…

This study looked at nearly 29,000 adults who had non-cardiac surgery in British Columbia, Canada. Researchers wanted to see how often doctors used a special breathing method called lung protective ventilation, which can prevent serious breathing problems after surgery. They also…

This study used a special imaging technique called electrical impedance tomography (EIT) to see how air moves in the lungs of 100 people with post-COVID-19 syndrome compared to 50 healthy volunteers. The goal was to understand why some people still feel short of breath after reco…

This study looked at whether people infected with COVID-19 who never had symptoms still develop antibodies. Researchers tested over 200 patients and their household members to compare immune responses between those with and without symptoms. The goal was to understand if asymptom…

This study examined the immune systems of 760 people who had recovered from COVID-19 to understand how their bodies fought the virus. Researchers measured antibodies and immune cells in blood samples over several months. The goal was to gather information that could improve tests…

This study looked at whether a blood test marker called NEU-SFL, which reflects immune cell activity, can help predict the risk of death in people hospitalized with COVID-19 in 2021. Researchers compared NEU-SFL levels between those who survived and those who did not. The goal wa…

This study reviewed medical records of 417 adults hospitalized with COVID-19 at four hospitals. Researchers wanted to find out how many patients also had other infections (co-infections) or got new infections later. They also looked at whether these extra infections affected deat…

This study looked back at medical records of 60 adults with blood cancers who had a stem cell transplant and later developed a rare fungal infection called mucormycosis. Researchers compared cases before and during the COVID-19 pandemic to see how the virus, new diagnostic tools,…

This study followed 530 working-age adults (18-70) who were hospitalized with COVID-19 to see how the disease affected their daily lives over 3 years. Researchers measured disability from both doctor and patient perspectives using standard checklists. The goal was to better under…

This study followed more than 4,200 Dutch COVID-19 patients for up to two years to learn about long COVID. Researchers tracked symptoms like tiredness, breathing problems, and mental health issues, and how these affected quality of life. The goal was to better understand the cond…

This study tested a quick-start program where people with COVID-19 could get tested and treated right away. It took place in Ghana, Malawi, Rwanda, Zambia, and Zimbabwe with 148 participants. Researchers interviewed patients, healthcare workers, and officials to see if the progra…

This study looked at ways to increase COVID-19 testing among Black/African American adults. Researchers tested whether culturally relevant videos and trusted community leaders could encourage more people to get tested. The study enrolled 327 people who visited beauty salons or ba…

This study looked at blood product shortages during the COVID-19 pandemic at a single hospital. Researchers tracked when emergency blood supplies were delayed or unavailable for 100 surgical patients. The goal was to use this information to create better policies for handling blo…

This study followed 51 adults who survived severe COVID-19 pneumonia and needed a breathing machine for more than 72 hours. Researchers checked their quality of life, physical strength, and nutrition at 1, 6, and 12 months after leaving the hospital. The goal was to understand lo…

This study looked at how stress from the COVID-19 pandemic affected eating behaviors and weight in over 5,000 English-speaking adults. Participants completed online surveys about their mental health, eating habits, and weight changes. The goal was to understand the connection bet…

This study reviewed medical records of 200 adults from an endocrinology clinic to see if taking vitamin D3 supplements lowered their chances of developing Long COVID after a COVID-19 infection or getting COVID-19 after vaccination. Researchers compared patients who took vitamin D…

This study tested a noninvasive device that measures breathing, heart rate, body temperature, and oxygen levels. Researchers wanted to see if it could help screen and monitor respiratory infections like COVID-19. Forty healthy adults performed breathing tasks while the device was…

This study followed 23 people who were hospitalized with severe COVID-19 to see if they developed blood sugar problems or diabetes later on. Researchers measured changes in blood sugar levels over three months. The goal was to understand if severe COVID-19 increases the risk of d…

This study looked at 120 hospitalized COVID-19 patients with severe breathing problems to understand how their immune systems were reacting. Researchers measured many immune markers in the blood to see if a specific immune pattern could predict who might die. The goal was to find…

This study looked for simple blood markers that could predict which patients with suspected COVID-19 would get worse after visiting the emergency room. Researchers followed 373 adults to see if routine lab tests could help identify those at risk of needing intensive care. The goa…

This study followed 283 adults who needed intensive care for severe COVID-19 lung problems. Researchers tracked who survived and how survivors were doing 4 years later, including their quality of life, breathing, and ability to work. No new treatments were tested—the goal was sim…

This study used health records from over 8 million COVID-19 patients in Taiwan to understand the disease's impact and how well the oral antiviral nirmatrelvir/ritonavir works in real-world settings. Researchers compared patients who did and did not receive the treatment to see wh…

This study looked back at the medical records of 84 hospitalized adults with severe COVID-19 who received the drug remdesivir. Researchers wanted to see how patients were doing 15 days after starting treatment. The goal was to learn what factors affected their recovery, not to te…

This study looked at over 600 veterans with chronic lung disease who had COVID-19 to understand what makes the illness worse and what help they need to recover. Researchers reviewed medical records and surveyed patients and their caregivers about their health, daily function, and…

This study examined over 1,000 vaccinated adults who later caught COVID-19. Researchers analyzed the virus's genetic code and measured antibody levels to see if certain variants were more common in these cases. The goal was to understand why infections still happen after vaccinat…

This study looked at whether a health education program in schools helped students and their parents learn more about COVID-19 and make safer choices. About 112 participants from several Miami-area schools took part. Researchers measured things like COVID-19 knowledge, confidence…

This study looked at how COVID-19 vaccination and boosters during pregnancy or breastfeeding affect immunity in mothers and their babies. Researchers measured antibody levels and virus-fighting ability in 150 mothers and infants over time. The goal was to understand how well the …

This study looked at 20 children under 18 who had heart inflammation (myocarditis) possibly linked to COVID-19. Researchers wanted to describe the symptoms, lab results, and heart ultrasound findings, and to figure out if the virus directly damages the heart or if the body's own …

This study followed 75 people with cystic fibrosis (CF) for two years to see how many developed antibodies from COVID-19 infection or vaccination. Researchers collected blood samples and health data to understand if CF patients have different immune responses or milder COVID-19 s…

This study looked at whether a community-designed program could help more people from minority ethnic groups, low-income households, and underserved migrants get vaccinated against COVID-19 and the flu. About 5,900 adults in East London took part. The main goal was to see if the …

This study looked at 175 hospitalized COVID-19 patients to understand why they develop dangerous blood clots. Researchers measured how quickly their blood forms clots using a special test. The goal was to find links between clotting problems and survival, which could help guide f…

This study tested two ways to get people who use opioids to take a COVID-19 test: having friends refer them, or having trained community members reach out directly. About 500 adults who had used opioids in the past 6 months took part. The goal was to see which method worked bette…

This study looked at how many people in Punta Arenas, Chile, experience persistent COVID-19—symptoms lasting more than 4 weeks after infection. Researchers surveyed and tested 282 adults who had COVID-19, checking for physical and mental health issues, and looking for risk factor…

This study looked at whether the virus that causes COVID-19 can be found in the saliva of people who have no symptoms or only mild symptoms. Researchers collected samples from the nose, mouth, eyes, and blood from 55 adults who either tested positive or lived with someone who did…

This study looked at whether text message reminders can encourage people with diabetes or at risk for diabetes to get tested for COVID-19. About 290 people in Georgia took part, with half getting the text reminders and the other half not. The goal was to see if the reminders incr…

This study looked at stored blood samples from about 300 adults hospitalized with COVID-19 to see if a protein called suPAR could predict who would develop severe breathing failure needing a ventilator. Researchers measured suPAR levels and checked medical records for outcomes. T…

This study analyzed blood samples from 304 COVID-19 patients to find early immune markers that could predict whether someone would become severely ill. By comparing immune cells and inflammatory signals in patients with mild versus severe disease, researchers aimed to identify cl…

This study looked at how often brainstem problems occur in COVID-19 patients who are on breathing machines and deeply sedated in the ICU. Researchers checked for nerve issues using a special scale and also examined heart rate patterns. The goal was to better understand how the vi…

This early study tested a new PET/CT scan tracer in 5 adults who had recovered from COVID-19. The goal was to see if the tracer could find signs of lung damage. The study was small and focused on testing the method, not treating the disease.

This study looked at how smoking changes immune cells and whether those changes make COVID-19 worse. Researchers followed 132 healthy smokers and non-smokers aged 30-55 for up to 6 months, taking blood, saliva, and nasal samples to track infections and immune responses. The goal …

This study looked at how well different COVID-19 vaccines work in adults from 7 countries. About 5,400 people joined within a day of getting their vaccine. Researchers measured immune responses and tracked any side effects to understand how the vaccines protect against COVID-19.

This study analyzed blood samples and health records from 818 adults hospitalized with COVID-19. Researchers looked for genetic, inflammatory, and biochemical clues that might explain why some patients become severely ill or die. The goal was to identify risk factors that could h…

This study looked at how the experimental COVID-19 drug ALG-097558 behaves in people with moderate liver impairment compared to healthy adults. Sixteen participants took the drug twice daily, and researchers measured drug levels in the blood and monitored side effects. The goal w…

This study looked at whether people with cystic fibrosis (CF) have natural protection against COVID-19. Researchers tested blood samples from 331 children and adults with CF in Europe over two years to see if they had antibodies from past infection or vaccination. The goal was to…

This study tested whether group discussions led by community members could change how people feel about COVID-19 testing and vaccines. 57 adults from housing agencies took part in Zoom meetings and filled out surveys over 6 months. The goal was to see if talking together could in…

This study looked at why Spanish-speaking Latinx communities face higher rates of COVID-19 infection and death. Researchers worked with community partners to understand social and ethical barriers to testing and vaccination. They tested a program that combined peer support and mo…

This study looked at 100 fully vaccinated adults who later tested positive for COVID-19. Researchers compared infection rates between people who only had the initial vaccine series and those who also got a booster shot. The goal was to understand how often breakthrough infections…

This study tested whether giving long-term care and retirement home staff a personal "resource navigator" could improve their overall wellness, reduce burnout, and increase COVID-19 vaccination. 123 staff members took part, with some getting one-on-one support and others not. The…

This study looked at 13 adults who had COVID-19 and still had symptoms like memory or nerve problems after recovery. Researchers used brain scans, memory tests, and other exams to find possible changes in the nervous system. The goal was to better understand long-term effects of …

This study looked at how the drug ALG-097558 behaves in people with severe kidney problems compared to healthy people. It involved 12 adults who took the drug twice daily. The goal was to see if kidney function affects drug levels and safety, not to test if it treats COVID-19.

This study looked at 600 COVID-19 patients with severe breathing problems who were treated with high-flow nasal oxygen and placed on their stomachs while awake. The goal was to see if this combination could reduce the need for breathing tubes and lower death rates. Researchers al…

This study followed 201 adults with diabetes who were hospitalized for COVID-19 in Algeria for up to one year after leaving the hospital. Researchers checked blood sugar control, weight, and kidney function at regular visits to see how the infection affected their diabetes long-t…

This study looked at placentas and umbilical cord blood from 68 women who had COVID-19 during pregnancy. Researchers checked for changes in the placenta's structure, genes, and signs of inflammation. The goal was to learn how the infection might affect the baby, not to test a tre…

This study looked at whether a person's genes influence how sick they get from COVID-19. Researchers collected blood or saliva samples from 721 people in the U.S. who tested positive for the virus. By analyzing their DNA, the team hopes to uncover genetic clues that could lead to…

This study looked back at medical records of 2,392 children who had non-heart surgery to see if having a mild cold before the operation increased risks after the COVID-19 pandemic. The goal was to help doctors decide the safest time to schedule surgery for children with cold symp…

This study followed 199 adults hospitalized with COVID-19 to better understand the disease. Researchers collected information on patient backgrounds, treatments used, and how the illness progressed over time. The goal was to answer important questions about COVID-19 without testi…

This study looked at whether it's safe and effective to give a COVID-19 booster and the flu shot at the same time. 36 healthy Thai adults took part. Researchers measured their immune responses to see if getting both vaccines together worked as well as getting them separately.

This study partnered with community organizations to make COVID-19 rapid testing easier and more effective for Latino communities in San Diego. Over 6,500 English- and Spanish-speaking adults from local clinics and neighborhoods took part. The goal was to find the best ways to of…

This study looked at whether it is safe to give another dose of a COVID-19 mRNA vaccine to people who had a bad reaction to a previous dose, or to people with a history of allergies. It also included people with long COVID. A total of 137 adults took part. The goal was to see how…

This study explored how changes in healthcare during the COVID-19 pandemic (2020-2021) impacted the quality of life and experiences of over 5,000 Dutch patients who had surgery or another medical procedure. Researchers used focus groups and surveys to understand what mattered mos…

This study tested whether group discussions led by community members could change how people feel about COVID-19 testing and vaccines. 49 adults from housing agencies took part in Zoom meetings and filled out surveys over 18 weeks. The goal was to see if these talks could increas…

This study explored whether a routine blood test called RDW (red blood cell distribution width) can help predict how severe COVID-19 patients in the intensive care unit will fare. Researchers looked at 146 adults with severe or critical COVID-19 to see if higher RDW levels were l…

This early-stage study tested a new drug called PA-001 in 47 healthy adults and older adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo through an IV. The goal was to find the right dose for future studies in COVID-19 pa…

This study tested a blood test that looks for signs of the body's immune response to COVID-19. The goal was to find infections that standard nose swab tests might miss and to better understand how the immune system fights the virus. About 950 adults took part, including people wi…

This study looked at how two different COVID-19 booster vaccines affect immune cells in the lymph nodes. Researchers took tiny samples from the lymph nodes of 12 adults who had already received at least three doses of an mRNA COVID-19 vaccine. They compared the immune response af…

This study tracked over 1,100 cancer patients and healthcare workers to understand how COVID-19 affects them. Researchers collected blood samples and health data to measure infection rates, severity, and immune responses. The goal was to learn how the virus spreads in cancer cent…

This study used advanced MRI scans to check for organ damage in 693 adults who had recovered from COVID-19. Researchers looked at the heart, kidneys, liver, lungs, pancreas, and spleen to see how often and how severely these organs were affected. The goal was to better understand…

This study looked at whether smoking or using nicotine products changes the chance of catching COVID-19. Researchers surveyed over 600 healthcare workers who had been tested for the virus. The goal was to see if there is a link between tobacco or nicotine use and testing positive…

This study looked at anxiety about COVID-19 in 200 adults with rheumatic diseases who were taking either biologic or conventional disease-modifying drugs. Researchers called participants and asked them to complete a questionnaire about their coronavirus-related anxiety. The goal …

This study looked at how COVID-19 causes organ failure in intensive care patients. Researchers tracked 380 adults with suspected or confirmed COVID-19 in the ICU, measuring kidney injury, breathing problems, and survival rates. The goal was to better understand the disease, not t…

This study aimed to find out how many healthy adults in central North Carolina had been exposed to COVID-19 by testing their blood for antibodies over one year. Participants were 643 adults aged 18 and older who did not have COVID-19 at the start. They provided blood samples and …

This study looked at whether virtual coaching helps rural pharmacists better counsel patients who are hesitant about the COVID-19 vaccine. Twenty pharmacies took part, first using standard training and then adding a personal video coach. Researchers measured how well pharmacists …

This study followed over 1,100 adults in the Netherlands who received monoclonal antibodies or antiviral pills for COVID-19. Researchers collected blood samples and nasal swabs over 90 days to measure how the virus and the body's immune response changed during treatment. The goal…

This study looked at whether certain medications used to treat COVID-19, or the COVID-19 vaccine itself, might affect a person's hearing. Researchers compared the hearing of 90 young adults who had COVID-19 (some took medication, some did not) to people who never had the virus. T…