Paxlovid rebound: new study tracks how often COVID returns after treatment
NCT ID NCT05618600
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study followed 917 adults with COVID-19 who were prescribed Paxlovid. Researchers wanted to see how often people test positive again after finishing the 5-day treatment. The goal is to better understand the so-called 'Paxlovid rebound' and help guide future care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Paxlovid
What this could lead to
If successful, this study could help doctors understand how often COVID-19 rebounds after Paxlovid treatment and who is most at risk.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove why rebound happens or how to prevent it. Results may not apply to everyone.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Scripps Research Institute
San Diego, California, 92126, United States