One shot for two viruses: combo Flu-COVID vaccine enters human testing
NCT ID NCT06680375
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This early-stage trial tested a new mRNA vaccine that combines protection against seasonal flu and COVID-19 in a single shot. Researchers gave the vaccine to 106 healthy adults aged 18-64 to check for side effects and measure immune responses. The goal is to see if a combined vaccine is safe and effective enough to simplify annual vaccinations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Combination mRNA vaccine targeting multiple flu strains and the SARS-CoV-2 spike protein
What this could lead to
If successful, this could lead to a single annual shot that protects against both flu and COVID-19, simplifying vaccination schedules.
What could go wrong
This is an early phase 1/2 trial with only 106 participants, so results may not apply to larger populations. The combination may cause more side effects or weaker immune responses than separate vaccines.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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GSK Investigational Site
Anniston, Alabama, 36207, United States
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GSK Investigational Site
Rolling Hills Estates, California, 90274, United States
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GSK Investigational Site
Hialeah, Florida, 33012, United States
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GSK Investigational Site
Miami, Florida, 33147, United States
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GSK Investigational Site
Miami, Florida, 33186, United States
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GSK Investigational Site
Lenexa, Kansas, 66219, United States
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GSK Investigational Site
St Louis, Missouri, 63141, United States
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GSK Investigational Site
Omaha, Nebraska, 68134, United States
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GSK Investigational Site
Rochester, New York, 14609, United States