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Simple Face-Down position may keep COVID-19 patients off ventilators

NCT ID NCT04358939

Completed Symptom relief Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether having conscious COVID-19 patients with breathing problems lie face down (prone position) while on high-flow oxygen could reduce the need for a breathing tube. Over 400 adults with COVID-19 pneumonia and mild to severe acute respiratory distress syndrome took part. The goal was to see if this simple positioning technique could improve outcomes and ease pressure on intensive care units.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
prone positioning
What this could lead to
If it works, this simple technique could reduce the need for intubation and free up critical care resources during COVID-19 surges.
What could go wrong
This is a completed trial, but results may not apply to all patients or future variants. The intervention is supportive, not a cure, and some patients may still require intubation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome adult acute respiratory distress syndrome COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE RESPIRATORY DISTRESS SYNDROME COVID-19

Contacts and locations

Locations

  • Intensive Care Unit, Hospital,

    Blois, 41016, France

  • Intensive Care Unit, Hospital, Argenteuil

    Argenteuil, 95100, France

  • Intensive Care Unit, Hospital, Dax

    Dax, 40107, France

  • Intensive Care Unit, Hospital, La Roche-sur-Yon

    La Roche-sur-Yon, 85925, France

  • Intensive Care Unit, Hospital, Le Mans

    Le Mans, 72037, France

  • Intensive Care Unit, Hospital, Valence

    Valence, 26953, France

  • Intensive Care Unit, Hospital, Vannes

    Vannes, 56017, France

  • Intensive Care Unit, Louis Mourier-APHP

    Colombes, 92700, France

  • Intensive Care Unit, University Hospital, Aix

    Aix-en-Provence, 13616, France

  • Intensive Care Unit, University Hospital, Lille

    Lille, 59037, France

  • Medical Intensive Care Unit, Hospital, Béthune

    Béthune, 62408, France

  • Medical Intensive Care Unit, Hospital, Orléans

    Orléans, 45067, France

  • Medical Intensive Care Unit, Tenon-APHP

    Paris, 75020, France

  • Medical Intensive Care Unit, University Hospital, Amiens

    Amiens, 80054, France

  • Medical Intensive Care Unit, University Hospital, Brest

    Brest, 29609, France

  • Medical Intensive Care Unit, University Hospital, Caen

    Caen, 14033, France

  • Medical Intensive Care Unit, University Hospital, Dijon

    Dijon, 21033, France

  • Medical Intensive Care Unit, University Hospital, Grenoble

    Grenoble, France

  • Medical Intensive Care Unit, University Hospital, Nancy

    Vandœuvre-lès-Nancy, 54511, France

  • Medical Intensive Care Unit, University Hospital, Nantes

    Nantes, 44093, France

  • Medical Intensive Care Unit, University Hospital, Nice

    Nice, 06202, France

  • Medical Intensive Care Unit, University Hospital, Poitiers

    Poitiers, 86021, France

  • Medical Intensive Care Unit, University Hospital, Tours

    Tours, 37044, France

  • Surgical Intensive Care Unit, University Hospital, Tours

    Tours, 37170, France

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