University Hospital, Tours

This study is testing whether a new, fast-track hospital protocol can improve survival and reduce long-term disability for patients who have had a serious type of stroke called a brain bleed. It will involve 600 patients across several French hospitals. The goal is to see if gett…

This study is testing if giving a diuretic drug (Furosemide) with IV fluids right after laser kidney stone surgery helps flush out tiny leftover stone fragments. The goal is to see if this 'forced diuresis' reduces the chance of these fragments sticking around and forming new sto…

This study aims to find the best way to help women give birth when their labor is induced and their cervix hasn't softened enough after 24 hours of initial treatment. It will compare two common approaches: giving the hormone oxytocin to start contractions versus repeating a cervi…

This study is testing a new type of talk therapy designed specifically for people with dissociative disorders, which cause feelings of detachment from oneself or reality. Researchers will compare this new therapy to standard care to see if it better reduces dissociative symptoms.…

This study is testing if a structured diet and exercise program can help adults with cystic fibrosis build more muscle. It is for people who are already taking a modern drug therapy (Elexacaftor-Tezacaftor-Ivacaftor). Researchers want to see if this combined lifestyle program imp…

This study is testing whether adding diuretics (water pills) as a second-line treatment is better than usual care for controlling high blood pressure in people with moderate to severe chronic kidney disease. It will enroll 720 patients who still have high blood pressure despite b…

This study is testing whether it is safe for ICU patients with severe breathing problems to continue eating and drinking normally, even if they might need a breathing tube. Currently, these patients are often told not to eat or drink to prevent food from going into their lungs du…

This study is testing if using hypnosis during a colonoscopy is as effective as using general anesthesia. It aims to see if hypnosis can reduce patient anxiety and pain, making the important cancer screening test more comfortable and accessible. The trial will involve 600 adults …

This study aims to find a new, easier way to diagnose Alzheimer's disease. Researchers will collect small tear samples from 90 people, including those with Alzheimer's and healthy volunteers. They will check if certain proteins and other substances in tears can reliably indicate …

This study is testing whether serving food in easy-to-grip, bite-sized pieces that residents can eat with their fingers helps improve nutrition and mealtime enjoyment. It will involve 30 elderly residents in care facilities who are at risk of undernutrition. Researchers will chec…

This study aims to understand why some children's acute leukemia returns or resists treatment by examining the bone marrow environment. Researchers will compare bone marrow cells from 40 children with leukemia to cells from children without blood diseases. The goal is to learn ho…

This study aims to understand how the thick mucus in the lungs of people with bronchiectasis might block a potential new inhaled antibody treatment. Researchers will collect mucus samples from 30 adult patients to test in the lab how well the treatment can move through the mucus …

This study aims to understand why morphine, a strong painkiller, often doesn't work well enough for adults with sickle cell disease during severe pain crises. Researchers will measure how quickly patients' kidneys filter morphine to see if faster filtration leads to underdosing. …