Could kidney function explain why morphine fails in sickle cell crises?
NCT ID NCT07246265
First seen Jan 04, 2026 · Last updated Apr 28, 2026 · Updated 18 times
Summary
This study looks at 100 adults with sickle cell disease who are in intensive care for severe pain crises. Researchers want to see if kidney function affects how the body clears morphine, which might explain why standard doses often don't relieve pain. By measuring morphine levels and kidney filtration, they hope to find the right dose for each patient.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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CH Le Mans
NOT_YET_RECRUITINGLe Mans, 72000, France
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CHRU de Tours
RECRUITINGTours, France, 37044, France
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CHU d'Orléans
NOT_YET_RECRUITINGOrléans, 45067, France
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CHU de Nantes
NOT_YET_RECRUITINGNantes, 44093, France
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CHU de Rennes
NOT_YET_RECRUITINGRennes, France
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Henri-Mondor
NOT_YET_RECRUITINGCréteil, France
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