Kidney test could unlock better pain relief for sickle cell patients in crisis

NCT ID NCT07246265

Recruiting now Knowledge-focused Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how quickly the kidneys clear morphine in sickle cell patients having a painful crisis. Researchers will measure kidney function and morphine levels in 100 intensive care patients to see if higher doses are needed for effective pain relief. The goal is to personalize morphine dosing based on each patient's kidney function.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE CHEST SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute chest syndrome sickle cell disease Vaso-Occlusive Crises

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE CHEST SYNDROME GLOMERULAR HYPERFILTRATION SICKLE CELL DISEASE SICKLE-CELL NEPHROPATHY VASO-OCCLUSIVE CRISES

Contacts and locations

Locations

CH Le Mans
NOT_YET_RECRUITING

Le Mans, 72000, France
CHRU de Tours
RECRUITING

Tours, France, 37044, France
CHU d'Orléans
NOT_YET_RECRUITING

Orléans, 45067, France
CHU de Nantes
NOT_YET_RECRUITING

Nantes, 44093, France
CHU de Rennes
NOT_YET_RECRUITING

Rennes, France
Henri-Mondor
NOT_YET_RECRUITING

Créteil, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.