New program aims to boost muscle in cystic fibrosis patients on trikafta

NCT ID NCT06457451

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a one-year program of remote exercise sessions and personalized diet advice can increase lean muscle mass in 100 adults with cystic fibrosis who are already taking the drug Trikafta. The program is designed to address new nutritional challenges, like weight gain and metabolic issues, that can arise with Trikafta. Researchers will measure changes in muscle mass, strength, and endurance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DIAPASOM program (dietary counseling and adapted physical activity)

What this could lead to

If successful, this program could help people with cystic fibrosis build and maintain muscle mass, improving their strength and overall health.

What could go wrong

This is a small, early-stage trial focused on a supportive therapy, not a cure. The program may not lead to significant muscle gain, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Cystic Fibrosis Resource and Competence Centre, Fondation Ildys, Roscoff

    RECRUITING

    Roscoff, 29684, France

    Contact

    Contact

  • Cystic Fibrosis Resource and Competence Centre, Hospital, Tours

    RECRUITING

    Vannes, 56017, France

    Contact

    Contact

  • Cystic Fibrosis Resource and Competence Centre, University Hospital, Angers

    RECRUITING

    Angers, 49033, France

    Contact

    Contact

  • Cystic Fibrosis Resource and Competence Centre, University Hospital, Tours

    RECRUITING

    Tours, 37044, France

    Contact

    Contact