Could a simple ear device ease chemo nausea without extra drugs?
NCT ID NCT04937309
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a non-invasive device that gently stimulates a nerve in the ear can help prevent nausea caused by chemotherapy in breast cancer patients. Participants use the device twice daily around their chemo sessions, alongside standard anti-nausea medication. The goal is to see if adding this stimulation reduces nausea more than standard care alone or a sham device.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
non-invasive auricular vagal stimulation device
What this could lead to
If effective, this device could offer a drug-free way to reduce nausea during chemotherapy, improving quality of life for breast cancer patients.
What could go wrong
This is a mid-sized trial testing a device that may not outperform a sham (fake) device. Nausea is subjective, and results may not apply to other cancers or chemotherapies.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CH BLOIS
ACTIVE_NOT_RECRUITINGBlois, France
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CHRU Bretonneau
RECRUITINGTours, France
Contact Email: •••••@•••••
Contact
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CORT37
RECRUITINGChambray-lès-Tours, France
Contact Email: •••••@•••••
Contact
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Ch Chateauroux
RECRUITINGChâteauroux, France
Contact Email: •••••@•••••
Contact
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Ch Chinon
RECRUITINGSaint-Benoît-la-Forêt, France
Contact Email: •••••@•••••
Contact
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Ch Orleans
ACTIVE_NOT_RECRUITINGOrléans, France
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Chru Morvan
RECRUITINGBrest, France
Contact Email: •••••@•••••
Contact
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Clinique Victor Hugo
RECRUITINGLe Mans, France
Contact Email: •••••@•••••
Contact