Could a simple ear device ease chemo nausea without extra drugs?

NCT ID NCT04937309

Recruiting now Symptom relief Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive device that gently stimulates a nerve in the ear can help prevent nausea caused by chemotherapy in breast cancer patients. Participants use the device twice daily around their chemo sessions, alongside standard anti-nausea medication. The goal is to see if adding this stimulation reduces nausea more than standard care alone or a sham device.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: non-invasive auricular vagal stimulation device
What this could lead to: If effective, this device could offer a drug-free way to reduce nausea during chemotherapy, improving quality of life for breast cancer patients.
What could go wrong: This is a mid-sized trial testing a device that may not outperform a sham (fake) device. Nausea is subjective, and results may not apply to other cancers or chemotherapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Nausea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

CH BLOIS
ACTIVE_NOT_RECRUITING

Blois, France
CHRU Bretonneau
RECRUITING

Tours, France
CORT37
RECRUITING

Chambray-lès-Tours, France
Ch Chateauroux
RECRUITING

Châteauroux, France
Ch Chinon
RECRUITING

Saint-Benoît-la-Forêt, France
Ch Orleans
ACTIVE_NOT_RECRUITING

Orléans, France
Chru Morvan
RECRUITING

Brest, France
Clinique Victor Hugo
RECRUITING

Le Mans, France

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