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Can COVID-19 and emergency surgery be safely managed together? a massive hospital study seeks answers

NCT ID NCT07719166

Knowledge-focused Sponsor: Pirogov Russian National Research Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This study looks at how COVID-19 and acute surgical conditions (like appendicitis or internal bleeding) affect each other in hospitalized adults. Researchers will analyze real-world data from a large hospital to understand treatment outcomes and develop models to predict in-hospital death. The goal is to improve surgical decision-making during pandemics.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better predict risks and choose safer surgical approaches for patients with COVID-19 who need emergency surgery.
What could go wrong
This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may be specific to one hospital and may not apply elsewhere.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

58,000 people

The number who actually took part.

Started

Mar 2020

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study cohort was assembled based on data from the Kommunarka Moscow Multidisciplinary Clinical Center (Moscow)-a facility repurposed to treat patients with COVID-19 alongside concurrent acute emergencies across surgical, cardiological, neurological, trauma, and neurosurgical specialties. It comprises medical data regarding the hospitalization and treatment outcomes of patients treated as inpatients during the pandemic period (March 1, 2020, to March 1, 2022) and the post-pandemic period (January 1, 2023, to December 31, 2024). De-identified data were derived from routine medical records and the hospital's medical information system. The dataset reflects real-world clinical practice in the care of patients with COVID-19 and acute surgical conditions, including abdominal, thrombotic, hemorrhagic, infectious-inflammatory, and other surgically significant pathologies.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older. * Hospitalization at the MMCC "Kommunarka". * A confirmed diagnosis of COVID-19 (based on current clinical guidelines). * Presence of one or more any acute surgical diseases (ASD) considered competing with COVID-19 or as a complication of COVID-19/its treatment, as per the discharge summary. * For specific sub-studies: Patients with acute surgical diseases of the abdominal organs. * For specific sub-studies: Patients with clinically significant spontaneous soft tissue hematomas or pneumomediastinum or other acute surgical diseases. Exclusion Criteria: * Patients for whom a diagnosis of COVID-19 was not established according to the discharge summary. * Patients for whom none of the studied acute surgical diseases were established according to the discharge summary. * Patients who underwent elective surgeries and developed COVID-19 in the postoperative period. * Patients operated on in another hospital and transferred with suspected COVID-19 (if not confirmed).

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Conditions

The condition(s) this trial relates to.

COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal surgery COVID-19 Emergency surgery Real-world data

Contacts and locations

Locations

  • Moscow Multidisciplinary Clinical Center Kommunarka

    Moscow, Russia

More trials for these conditions

Other studies related to the condition(s) this trial covers.