Lying face-down with high-flow oxygen may help COVID-19 patients avoid breathing tubes
NCT ID NCT05178212
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 600 COVID-19 patients with severe breathing problems who were treated with high-flow nasal oxygen and asked to lie face-down (awake prone position). The goal was to see if this combination reduced the need for a breathing tube and lowered death rates. Researchers also wanted to find out which patients were most likely to need a breathing tube despite this treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could confirm that combining high-flow oxygen with awake prone positioning reduces the need for breathing tubes in COVID-19 patients.
- What could go wrong
- This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ACUTE RESPIRATORY FAILURE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mariano Esperatti
Mar del Plata, Buenos Aires, 7600, Argentina
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Spinal zaps could reboot breathing after brain injury
- Five years on: how does long COVID evolve?
- Can a targeted pill tame severe COVID-19?
- Could starting feeds sooner shield preterm babies from infection?
- Can an organic compound tame COVID-19 in High-Risk patients?
- Could exercise retrain the heart in long COVID?