Lying face-down with high-flow oxygen may help COVID-19 patients avoid breathing tubes
NCT ID NCT05178212
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 600 COVID-19 patients with severe breathing problems who were treated with high-flow nasal oxygen and asked to lie face-down (awake prone position). The goal was to see if this combination reduced the need for a breathing tube and lowered death rates. Researchers also wanted to find out which patients were most likely to need a breathing tube despite this treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could confirm that combining high-flow oxygen with awake prone positioning reduces the need for breathing tubes in COVID-19 patients.
What could go wrong
This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients or settings.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mariano Esperatti
Mar del Plata, Buenos Aires, 7600, Argentina