MORTALITY

This study tests if a 24-hour active drain placed under the scalp works as well as a 24-hour passive drain placed under the brain's outer layer after surgery for chronic subdural hematoma (a blood clot on the brain). About 354 adults in Denmark will take part. The goal is to see …

This study tests whether adding the antibiotic minocycline to standard stroke care helps people with moderate strokes recover better. About 1,164 adults will be randomly assigned to receive either minocycline pills for five days plus usual care, or usual care alone. Researchers w…

This study observes rehabilitation practices in intensive care units (ICUs) around the world for patients who need a breathing machine (mechanical ventilation) for at least 48 hours. Researchers want to understand what types of rehab are used, how often, and how they affect patie…

This study follows 10,000 adults aged 18 and older for life to see if simple health measurements can predict how long and how well people age. Researchers will track deaths, diseases, and disabilities to find early warning signs. No treatments or drugs are tested—just observation…

This study looks at how well pneumococcal vaccines work in children (0-18 years) across France. Researchers will collect data from 2,500 children with invasive pneumococcal infections to see which serotypes cause disease and whether vaccinated children have less severe illness. T…