MORTALITY
Clinical trials for MORTALITY explained in plain language.
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Simple position change could help COVID patients avoid ventilators
Disease control CompletedThis study looked at a non-invasive treatment for adults with severe COVID-19 who were struggling to breathe. It combined high-flow oxygen through the nose with having patients lie on their stomachs while awake. The goal was to see if this approach could help patients avoid needi…
Matched conditions: MORTALITY
Sponsor: Hospital Privado de Comunidad de Mar del Plata • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Mail-Order fitness plan tested on 50,000 women to fight heart disease and falls
Disease control CompletedThis large study tested whether sending exercise guides and motivational tips through the mail could help older women become more active and improve their health. It enrolled nearly 50,000 women aged 60+ to see if this remote program could reduce serious health problems like hear…
Matched conditions: MORTALITY
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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Trial aims to stop deadly gut infection in High-Risk patients
Disease control CompletedThis study tested if adding the drug bezlotoxumab to standard care could prevent severe outcomes in patients with a dangerous C. difficile gut infection. It focused on 44 patients identified as high-risk using a special score based on their genes, blood tests, and gut bacteria. T…
Matched conditions: MORTALITY
Phase: PHASE2 • Sponsor: Hellenic Institute for the Study of Sepsis • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Could changing a vaccine age rule halve child deaths?
Prevention CompletedThis study tested whether a national policy that stops offering measles vaccine after a child's first birthday affects child survival. Researchers compared two groups of children aged 9-35 months in Guinea-Bissau: one followed the standard policy, and the other received the measl…
Matched conditions: MORTALITY
Phase: PHASE4 • Sponsor: Bandim Health Project • Aim: Prevention
Last updated Mar 30, 2026 14:31 UTC
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Surgery side effects double threat: confusion and weakness linked to higher death risk in seniors
Knowledge-focused CompletedThis study followed 6,196 adults aged 65+ having non-emergency surgery to understand how post-surgery confusion (delirium) affects physical frailty and survival. Researchers tracked patients' strength and health before surgery, checked for confusion after surgery, and followed up…
Matched conditions: MORTALITY
Sponsor: Chinese PLA General Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Video camera could make ICU vital checks more reliable
Knowledge-focused CompletedThis study tested if using a video camera is better than the human eye for measuring a simple vital sign called 'capillary refill time' in intensive care patients. The goal was to see if the video method gives more consistent results when different people take the measurement. It…
Matched conditions: MORTALITY
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Researchers hunt for clues to predict which advanced cancer patients are at highest risk after ER visit
Knowledge-focused CompletedThis study looked back at the medical records of 1,250 patients with advanced cancer who visited a hospital emergency department. The goal was to find common factors—like lab test results, overall health, and nutrition—that are linked to a higher risk of dying within 90 days of t…
Matched conditions: MORTALITY
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Can a simple blood test predict your survival after a heart attack?
Knowledge-focused CompletedThis study looked at 1000 patients who had a major heart attack (STEMI) to see if their nutritional status, measured by simple blood tests at the hospital, could predict their health outcomes over the next two years. Researchers used two scoring systems (CONUT and PNI) based on b…
Matched conditions: MORTALITY
Sponsor: Muğla Sıtkı Koçman University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:28 UTC
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Does donating a kidney hurt your heart? massive study seeks answers
Knowledge-focused CompletedThis study aims to understand the long-term heart health and survival of people who donate a kidney. Researchers will compare health records of 50,000 living kidney donors in Canada to a carefully matched group of healthy people who did not donate. The goal is to see if donors ha…
Matched conditions: MORTALITY
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:26 UTC