Does extra oxygen during heart surgery protect kidneys? new pilot study investigates.

NCT ID NCT07510672

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study looked at whether giving extra oxygen during heart surgery (when a heart-lung machine is used) affects kidney function afterward. 104 adults having elective heart surgery were randomly assigned to receive either high or normal oxygen levels. The main goal was to see if extra oxygen could reduce kidney problems. The study is complete, but because it's a small pilot, the results are not definitive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
extra oxygen (hyperoxia)
What this could lead to
If it works, this could point toward safer oxygen levels during heart surgery to protect the kidneys.
What could go wrong
This is a small pilot study, so results may not be conclusive. The approach is still experimental and may not improve outcomes.

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Conditions

The condition(s) this trial relates to.

acute kidney injury Arrhythmias, Cardiac cardiac rhythm disease Hyperoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Padova University Hospital

    Padova, PD, 35121, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.