Could starting dialysis sooner save more hearts?
NCT ID NCT07756801
First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time
Summary
This trial asks whether starting dialysis early—within 6 hours—in patients with cardiogenic shock and fluid overload can reduce deaths in the hospital compared to waiting until it's clearly needed. It enrolls adults in intensive care with severe heart pump failure and signs of excess fluid. The study compares immediate dialysis to the current standard of care, tracking survival, need for additional heart support, and recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Immediate renal replacement therapy (dialysis) started within 6 hours of randomization
- What this could lead to
- If early dialysis proves better, it could establish a new standard of care that lowers death rates in critically ill patients with cardiogenic shock and fluid overload.
- What could go wrong
- The trial is still testing this approach, and early dialysis carries risks like infection, blood pressure drops, and complications from the procedure. It may not improve outcomes and could add unnecessary treatment burden.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Ottawa Heart Institute
Ottawa, Ontario, K1Y 4W7, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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