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A simple urine test and a smart alert may help predict kidney failure in sick kids

NCT ID NCT07718464

Recruiting now Disease control Sponsor: Children's Hospital Medical Center, Cincinnati Source: ClinicalTrials.gov ↗

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This study tests whether adding a clinical decision support tool to the electronic medical record helps doctors use the furosemide stress test in critically ill children at high risk for acute kidney injury. The furosemide stress test measures how the kidneys respond to a diuretic, which may predict whether a child will need dialysis. Researchers will compare outcomes in the two years after the tool is introduced with the two years before, focusing on fluid buildup and the need for kidney replacement therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a clinical decision support tool for the furosemide stress test
What this could lead to
If successful, this tool could help doctors identify children at risk for severe kidney injury earlier and reduce dangerous fluid buildup, potentially avoiding the need for dialysis.
What could go wrong
This is a single-center study comparing outcomes before and after the tool is introduced, not a randomized trial, so other factors could influence results. The tool itself does not treat kidney injury—it only guides testing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE KIDNEY INJURY PEDIATRIC INTENSIVE CARE UNIT RENAL REPLACEMENT THERAPY

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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